SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wul'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_2
(ANDROGEN RECEPTOR)		 2wul GLUTAREDOXIN RELATED
PROTEIN 5
(Homo
sapiens) 		4 / 7 LEU A  77
LEU A 147
MET A 128
LEU A 138
 None
 1.01A 4okwA-2wulA:
undetectable		 4okwA-2wulA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_I_IPHI101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 2wul GLUTAREDOXIN RELATED
PROTEIN 5
(Homo
sapiens) 		4 / 6 VAL A  82
HIS A  80
LEU A 138
LEU A 125
 None
 1.25A 5hrqB-2wulA:
undetectable
5hrqI-2wulA:
undetectable
5hrqJ-2wulA:
undetectable		 5hrqB-2wulA:
13.89
5hrqI-2wulA:
16.67
5hrqJ-2wulA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 2wul GLUTAREDOXIN RELATED
PROTEIN 5
(Homo
sapiens) 		4 / 8 LEU A  96
ALA A  47
VAL A  90
GLN A 111
 None
 1.02A 5nu7A-2wulA:
undetectable		 5nu7A-2wulA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA503_1
(-)		 2wul GLUTAREDOXIN RELATED
PROTEIN 5
(Homo
sapiens) 		5 / 9 LEU A 125
VAL A  74
LEU A  77
PRO A  62
ALA A  87
 None
 1.37A 5og9A-2wulA:
undetectable		 5og9A-2wulA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7Z_A_BHAA201_0
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 2wul GLUTAREDOXIN RELATED
PROTEIN 5
(Homo
sapiens) 		4 / 6 LEU A 125
VAL A 112
LEU A 114
VAL A  56
 None
 0.98A 5x7zA-2wulA:
undetectable		 5x7zA-2wulA:
26.11