SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wuq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CMA_B_SAMB105_0 (PROTEIN (MET REPRESSOR))	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 11	ARG A 304 LEU A 11 GLU A 10 HIS A 16 GLY A 19	None	1.11A	1cmaA-2wuqA: undetectable 1cmaB-2wuqA: undetectable	1cmaA-2wuqA: 14.29 1cmaB-2wuqA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERE_E_ESTE600_1 (ESTROGEN RECEPTOR)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	4 / 8	MET A 144 ALA A 116 LEU A 101 LEU A 53	None	0.96A	1ereE-2wuqA: undetectable	1ereE-2wuqA: 24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ERE_F_ESTF600_1 (ESTROGEN RECEPTOR)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	4 / 8	MET A 144 ALA A 116 LEU A 101 LEU A 53	None	0.95A	1ereF-2wuqA: undetectable	1ereF-2wuqA: 24.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GHM_A_CEDA1_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	ALA A 46 SER A 47 LYS A 50 SER A 109 LYS A 254 GLY A 256	None	0.30A	1ghmA-2wuqA: 27.4	1ghmA-2wuqA: 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I2W_A_CFXA1300_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	ALA A 46 SER A 47 LYS A 50 SER A 109 LYS A 254 GLY A 256	None	0.31A	1i2wA-2wuqA: 29.8	1i2wA-2wuqA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1I2W_B_CFXB2300_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 12	ALA A 46 SER A 47 LYS A 50 SER A 109 GLY A 256	None	0.18A	1i2wB-2wuqA: 29.9	1i2wB-2wuqA: 24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KB9_A_PCFA514_0 (CYTOCHROME B CYTOCHROME C1, HEME PROTEIN UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX CORE PROTEIN I UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	4 / 8	SER A 105 ILE A 61 VAL A 126 MET A 129	None	1.06A	1kb9A-2wuqA: undetectable 1kb9C-2wuqA: undetectable 1kb9D-2wuqA: 0.0 1kb9E-2wuqA: undetectable	1kb9A-2wuqA: 21.44 1kb9C-2wuqA: 21.65 1kb9D-2wuqA: 20.38 1kb9E-2wuqA: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_A_SAMA200_0 (METHIONINE REPRESSOR)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 11	ARG A 304 LEU A 11 GLU A 10 HIS A 16 GLY A 19	None	1.13A	1mjqA-2wuqA: undetectable 1mjqB-2wuqA: undetectable	1mjqA-2wuqA: 14.29 1mjqB-2wuqA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MJQ_I_SAMI199_0 (METHIONINE REPRESSOR)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 11	ARG A 304 LEU A 11 GLU A 10 HIS A 16 GLY A 19	None	1.14A	1mjqI-2wuqA: undetectable 1mjqJ-2wuqA: undetectable	1mjqI-2wuqA: 14.29 1mjqJ-2wuqA: 14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1N13_B_AG2B7011_1 (PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE ALPHA CHAIN PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE BETA CHAIN)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	4 / 5	GLU A 200 LEU A 29 ASP A 28 LEU A 309	None	1.23A	1n13B-2wuqA: undetectable 1n13C-2wuqA: undetectable	1n13B-2wuqA: 15.46 1n13C-2wuqA: 12.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD4_B_CHDB927_0 (FERROCHELATASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	3 / 3	LEU A 43 PRO A 44 ARG A 262	None	0.49A	2qd4B-2wuqA: undetectable	2qd4B-2wuqA: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MZE_A_CFXA364_1 (D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACA)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	ALA A 46 SER A 47 LYS A 50 THR A 255 GLY A 256 ARG A 239	None	0.65A	3mzeA-2wuqA: 21.4	3mzeA-2wuqA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NY4_A_SMXA308_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	7 / 12	SER A 47 SER A 109 ARG A 239 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.59A	3ny4A-2wuqA: 28.7	3ny4A-2wuqA: 25.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OU7_A_SAMA300_0 (SAM-DEPENDENT METHYLTRANSFERASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 12	LEU A 53 ALA A 113 GLY A 111 MET A 144 LEU A 101	None	1.22A	3ou7A-2wuqA: undetectable	3ou7A-2wuqA: 24.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q1E_D_T44D328_1 (5-HYDROXYISOURATE HYDROLASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 9	LEU A 230 LEU A 227 THR A 57 LEU A 117 LEU A 53	None	1.25A	3q1eB-2wuqA: undetectable 3q1eD-2wuqA: undetectable	3q1eB-2wuqA: 20.16 3q1eD-2wuqA: 20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SH8_A_CEDA1_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	ALA A 46 SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256	None	0.34A	3sh8A-2wuqA: 29.8	3sh8A-2wuqA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SH8_B_CEDB1_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	ALA A 46 SER A 47 LYS A 50 SER A 109 LYS A 254 GLY A 256	None	0.40A	3sh8B-2wuqA: 29.6	3sh8B-2wuqA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SH8_B_CEDB1_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	SER A 47 LYS A 50 SER A 109 LYS A 254 GLY A 256 ARG A 239	None	1.04A	3sh8B-2wuqA: 29.6	3sh8B-2wuqA: 23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4B7Q_A_ZMRA601_2 (NEURAMINIDASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	3 / 3	ARG A 12 ARG A 9 ILE A 37	None GOL A1317 (-3.9A) None	0.94A	4b7qA-2wuqA: undetectable	4b7qA-2wuqA: 18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EUZ_A_MEMA401_1 (CARBAPENEM-HYDROLIZI NG BETA-LACTAMASE SFC-1)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	LYS A 50 SER A 109 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.39A	4euzA-2wuqA: 30.9	4euzA-2wuqA: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EYS_A_ACTA402_0 (MCCC FAMILY PROTEIN)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 6	SER A 109 ASP A 110 SER A 114 ASP A 115 ARG A 145	None	1.44A	4eysA-2wuqA: undetectable	4eysA-2wuqA: 23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I1R_A_LZUA801_1 (MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 12	VAL A 26 VAL A 280 ALA A 299 LEU A 305 LEU A 15	None	1.12A	4i1rA-2wuqA: undetectable	4i1rA-2wuqA: 22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLR_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	4 / 8	LEU A 138 SER A 23 VAL A 267 GLY A 266	None	0.97A	4klrB-2wuqA: undetectable	4klrB-2wuqA: 22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N9K_A_CEDA301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	ALA A 46 SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256	None	0.36A	4n9kA-2wuqA: 30.1	4n9kA-2wuqA: 24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N9K_B_CEDB301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	ALA A 46 SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256	None	0.30A	4n9kB-2wuqA: 30.2	4n9kB-2wuqA: 24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OT2_A_NPSA602_1 (SERUM ALBUMIN)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	4 / 6	ARG A 306 ALA A 302 ASP A 307 LEU A 240	None	0.90A	4ot2A-2wuqA: undetectable	4ot2A-2wuqA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GHY_B_CEDB301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 12	ALA A 46 SER A 47 SER A 109 LYS A 254 GLY A 256	None	0.30A	5ghyB-2wuqA: 30.0	5ghyB-2wuqA: 25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GHZ_A_CEDA301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 11	ALA A 46 SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256	None	0.34A	5ghzA-2wuqA: 30.1	5ghzA-2wuqA: 25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5GHZ_B_CEDB301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 10	ALA A 46 SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256	None	0.35A	5ghzB-2wuqA: 30.1	5ghzB-2wuqA: 25.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HIE_B_P06B801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	4 / 7	ILE A 37 GLY A 36 LEU A 138 ASP A 40	None	0.84A	5hieB-2wuqA: undetectable	5hieB-2wuqA: 22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KPC_B_SAMB401_0 (PAVINE N-METHYLTRANSFERASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 12	PHE A 24 SER A 23 GLY A 36 ASP A 28 ALA A 192	None	1.11A	5kpcB-2wuqA: undetectable	5kpcB-2wuqA: 23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OM3_B_DXTB501_1 (ALPHA-1-ANTICHYMOTRY PSIN)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	4 / 6	SER A 114 PHE A 118 ASP A 115 HIS A 142	None	1.20A	5om3A-2wuqA: undetectable 5om3B-2wuqA: undetectable	5om3A-2wuqA: 11.01 5om3B-2wuqA: 8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VEU_A_RITA602_1 (CYTOCHROME P450 3A5)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 12	LEU A 219 PHE A 135 ALA A 54 THR A 106 GLY A 266	None	1.04A	5veuA-2wuqA: undetectable	5veuA-2wuqA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VEU_B_RITB602_1 (CYTOCHROME P450 3A5)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 12	LEU A 219 PHE A 135 ALA A 54 THR A 106 GLY A 266	None	0.97A	5veuB-2wuqA: undetectable	5veuB-2wuqA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VEU_H_RITH602_1 (CYTOCHROME P450 3A5)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 12	LEU A 219 PHE A 135 ALA A 54 THR A 106 GLY A 266	None	0.98A	5veuH-2wuqA: undetectable	5veuH-2wuqA: 21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AK3_A_P2EA1201_1 (PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	4 / 4	PRO A 44 MET A 144 GLY A 111 VAL A 49	None	1.38A	6ak3A-2wuqA: undetectable	6ak3A-2wuqA: 15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_B_9F2B400_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	7 / 12	SER A 47 SER A 109 ARG A 239 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.49A	6b5yB-2wuqA: 29.0	6b5yB-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_D_9F2D400_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	7 / 12	SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256 THR A 257 GLU A 295	None	0.69A	6b5yD-2wuqA: 28.8	6b5yD-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_B_9F2B301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.28A	6b68B-2wuqA: 29.0	6b68B-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_D_9F2D400_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	7 / 12	SER A 47 SER A 109 ARG A 239 LYS A 254 GLY A 256 THR A 257 GLU A 295	None	0.57A	6b68D-2wuqA: 29.0	6b68D-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_B_9F2B301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.25A	6b69A-2wuqA: 29.0 6b69B-2wuqA: 29.0	6b69A-2wuqA: 14.55 6b69B-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_D_9F2D301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	8 / 12	SER A 47 SER A 109 ARG A 239 LYS A 254 THR A 255 GLY A 256 THR A 257 GLU A 295	None	0.47A	6b69D-2wuqA: 28.9	6b69D-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_B_9F2B301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	7 / 12	SER A 47 SER A 109 ARG A 239 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.40A	6b6aB-2wuqA: 29.0	6b6aB-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_D_9F2D301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	8 / 12	SER A 47 SER A 109 ARG A 239 LYS A 254 THR A 255 GLY A 256 THR A 257 GLU A 295	None	0.54A	6b6aD-2wuqA: 28.9	6b6aD-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6C_A_9F2A301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	7 / 12	SER A 47 SER A 109 ARG A 239 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.48A	6b6cA-2wuqA: 29.0	6b6cA-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6D_A_9F2A302_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.47A	6b6dA-2wuqA: 14.2	6b6dA-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6E_A_9F2A302_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	7 / 12	SER A 47 SER A 109 ARG A 239 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.46A	6b6eA-2wuqA: 28.9	6b6eA-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6F_A_9F2A301_1 (BETA-LACTAMASE)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	6 / 12	SER A 47 SER A 109 LYS A 254 THR A 255 GLY A 256 THR A 257	None	0.53A	6b6fA-2wuqA: 28.7	6b6fA-2wuqA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN8_A_HFGA603_0 (UNCHARACTERIZED PROTEIN)	2wuq	BETA-LACTAMASE REGULATORY PROTEIN BLAB (Streptomyces cacaoi)	5 / 12	LEU A 198 VAL A 130 PRO A 52 SER A 109 GLY A 111	None	1.34A	6mn8A-2wuqA: undetectable	6mn8A-2wuqA: 19.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1CMA_B_SAMB105_0","PROTEIN (MET REPRESSOR)","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"ARG A 304;LEU A  11;GLU A  10;HIS A  16;GLY A  19","None","1.11A","1cmaA-2wuqA:undetectable;1cmaB-2wuqA:undetectable","1cmaA-2wuqA:14.29;1cmaB-2wuqA:14.29"],["1ERE_E_ESTE600_1","ESTROGEN RECEPTOR","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",4,"MET A 144;ALA A 116;LEU A 101;LEU A  53","None","0.96A","1ereE-2wuqA:undetectable","1ereE-2wuqA:24.34"],["1ERE_F_ESTF600_1","ESTROGEN RECEPTOR","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",4,"MET A 144;ALA A 116;LEU A 101;LEU A  53","None","0.95A","1ereF-2wuqA:undetectable","1ereF-2wuqA:24.34"],["1GHM_A_CEDA1_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"ALA A  46;SER A  47;LYS A  50;SER A 109;LYS A 254;GLY A 256","None","0.30A","1ghmA-2wuqA:27.4","1ghmA-2wuqA:22.73"],["1I2W_A_CFXA1300_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"ALA A  46;SER A  47;LYS A  50;SER A 109;LYS A 254;GLY A 256","None","0.31A","1i2wA-2wuqA:29.8","1i2wA-2wuqA:24.06"],["1I2W_B_CFXB2300_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"ALA A  46;SER A  47;LYS A  50;SER A 109;GLY A 256","None","0.18A","1i2wB-2wuqA:29.9","1i2wB-2wuqA:24.06"],["1KB9_A_PCFA514_0","CYTOCHROME B;CYTOCHROME C1, HEME PROTEIN;UBIQUINOL-CYTOCHROME C REDUCTASE COMPLEX CORE PROTEIN I;UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",4,"SER A 105;ILE A  61;VAL A 126;MET A 129","None","1.06A","1kb9A-2wuqA:undetectable;1kb9C-2wuqA:undetectable;1kb9D-2wuqA:0.0;1kb9E-2wuqA:undetectable","1kb9A-2wuqA:21.44;1kb9C-2wuqA:21.65;1kb9D-2wuqA:20.38;1kb9E-2wuqA:20.00"],["1MJQ_A_SAMA200_0","METHIONINE REPRESSOR","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"ARG A 304;LEU A  11;GLU A  10;HIS A  16;GLY A  19","None","1.13A","1mjqA-2wuqA:undetectable;1mjqB-2wuqA:undetectable","1mjqA-2wuqA:14.29;1mjqB-2wuqA:14.29"],["1MJQ_I_SAMI199_0","METHIONINE REPRESSOR","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"ARG A 304;LEU A  11;GLU A  10;HIS A  16;GLY A  19","None","1.14A","1mjqI-2wuqA:undetectable;1mjqJ-2wuqA:undetectable","1mjqI-2wuqA:14.29;1mjqJ-2wuqA:14.29"],["1N13_B_AG2B7011_1","PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE ALPHA CHAIN;PYRUVOYL-DEPENDENT ARGININE DECARBOXYLASE BETA CHAIN","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",4,"GLU A 200;LEU A  29;ASP A  28;LEU A 309","None","1.23A","1n13B-2wuqA:undetectable;1n13C-2wuqA:undetectable","1n13B-2wuqA:15.46;1n13C-2wuqA:12.15"],["2QD4_B_CHDB927_0","FERROCHELATASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",3,"LEU A  43;PRO A  44;ARG A 262","None","0.49A","2qd4B-2wuqA:undetectable","2qd4B-2wuqA:22.34"],["3MZE_A_CFXA364_1","D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACA","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"ALA A  46;SER A  47;LYS A  50;THR A 255;GLY A 256;ARG A 239","None","0.65A","3mzeA-2wuqA:21.4","3mzeA-2wuqA:23.08"],["3NY4_A_SMXA308_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",7,"SER A  47;SER A 109;ARG A 239;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.59A","3ny4A-2wuqA:28.7","3ny4A-2wuqA:25.62"],["3OU7_A_SAMA300_0","SAM-DEPENDENT METHYLTRANSFERASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"LEU A  53;ALA A 113;GLY A 111;MET A 144;LEU A 101","None","1.22A","3ou7A-2wuqA:undetectable","3ou7A-2wuqA:24.36"],["3Q1E_D_T44D328_1","5-HYDROXYISOURATE HYDROLASE;5-HYDROXYISOURATE HYDROLASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"LEU A 230;LEU A 227;THR A  57;LEU A 117;LEU A  53","None","1.25A","3q1eB-2wuqA:undetectable;3q1eD-2wuqA:undetectable","3q1eB-2wuqA:20.16;3q1eD-2wuqA:20.16"],["3SH8_A_CEDA1_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"ALA A  46;SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256","None","0.34A","3sh8A-2wuqA:29.8","3sh8A-2wuqA:23.38"],["3SH8_B_CEDB1_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"ALA A  46;SER A  47;LYS A  50;SER A 109;LYS A 254;GLY A 256","None","0.40A","3sh8B-2wuqA:29.6","3sh8B-2wuqA:23.38"],["3SH8_B_CEDB1_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"SER A  47;LYS A  50;SER A 109;LYS A 254;GLY A 256;ARG A 239","None","1.04A","3sh8B-2wuqA:29.6","3sh8B-2wuqA:23.38"],["4B7Q_A_ZMRA601_2","NEURAMINIDASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",3,"ARG A  12;ARG A   9;ILE A  37","None;GOL A1317 (-3.9A);None","0.94A","4b7qA-2wuqA:undetectable","4b7qA-2wuqA:18.30"],["4EUZ_A_MEMA401_1","CARBAPENEM-HYDROLIZING BETA-LACTAMASE SFC-1","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"LYS A  50;SER A 109;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.39A","4euzA-2wuqA:30.9","4euzA-2wuqA:23.12"],["4EYS_A_ACTA402_0","MCCC FAMILY PROTEIN","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"SER A 109;ASP A 110;SER A 114;ASP A 115;ARG A 145","None","1.44A","4eysA-2wuqA:undetectable","4eysA-2wuqA:23.40"],["4I1R_A_LZUA801_1","MUCOSA-ASSOCIATED LYMPHOID TISSUE LYMPHOMA TRANSLOCATION PROTEIN 1","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"VAL A  26;VAL A 280;ALA A 299;LEU A 305;LEU A  15","None","1.12A","4i1rA-2wuqA:undetectable","4i1rA-2wuqA:22.95"],["4KLR_B_CHDB503_0","FERROCHELATASE, MITOCHONDRIAL","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",4,"LEU A 138;SER A  23;VAL A 267;GLY A 266","None","0.97A","4klrB-2wuqA:undetectable","4klrB-2wuqA:22.25"],["4N9K_A_CEDA301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"ALA A  46;SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256","None","0.36A","4n9kA-2wuqA:30.1","4n9kA-2wuqA:24.77"],["4N9K_B_CEDB301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"ALA A  46;SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256","None","0.30A","4n9kB-2wuqA:30.2","4n9kB-2wuqA:24.77"],["4OT2_A_NPSA602_1","SERUM ALBUMIN","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",4,"ARG A 306;ALA A 302;ASP A 307;LEU A 240","None","0.90A","4ot2A-2wuqA:undetectable","4ot2A-2wuqA:21.12"],["5GHY_B_CEDB301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"ALA A  46;SER A  47;SER A 109;LYS A 254;GLY A 256","None","0.30A","5ghyB-2wuqA:30.0","5ghyB-2wuqA:25.08"],["5GHZ_A_CEDA301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"ALA A  46;SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256","None","0.34A","5ghzA-2wuqA:30.1","5ghzA-2wuqA:25.08"],["5GHZ_B_CEDB301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"ALA A  46;SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256","None","0.35A","5ghzB-2wuqA:30.1","5ghzB-2wuqA:25.08"],["5HIE_B_P06B801_2","SERINE\/THREONINE-PROTEIN KINASE B-RAF","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",4,"ILE A  37;GLY A  36;LEU A 138;ASP A  40","None","0.84A","5hieB-2wuqA:undetectable","5hieB-2wuqA:22.16"],["5KPC_B_SAMB401_0","PAVINE N-METHYLTRANSFERASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"PHE A  24;SER A  23;GLY A  36;ASP A  28;ALA A 192","None","1.11A","5kpcB-2wuqA:undetectable","5kpcB-2wuqA:23.06"],["5OM3_B_DXTB501_1","ALPHA-1-ANTICHYMOTRYPSIN;ALPHA-1-ANTICHYMOTRYPSIN","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",4,"SER A 114;PHE A 118;ASP A 115;HIS A 142","None","1.20A","5om3A-2wuqA:undetectable;5om3B-2wuqA:undetectable","5om3A-2wuqA:11.01;5om3B-2wuqA:8.36"],["5VEU_A_RITA602_1","CYTOCHROME P450 3A5","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"LEU A 219;PHE A 135;ALA A  54;THR A 106;GLY A 266","None","1.04A","5veuA-2wuqA:undetectable","5veuA-2wuqA:21.27"],["5VEU_B_RITB602_1","CYTOCHROME P450 3A5","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"LEU A 219;PHE A 135;ALA A  54;THR A 106;GLY A 266","None","0.97A","5veuB-2wuqA:undetectable","5veuB-2wuqA:21.27"],["5VEU_H_RITH602_1","CYTOCHROME P450 3A5","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"LEU A 219;PHE A 135;ALA A  54;THR A 106;GLY A 266","None","0.98A","5veuH-2wuqA:undetectable","5veuH-2wuqA:21.27"],["6AK3_A_P2EA1201_1","PROSTAGLANDIN E2 RECEPTOR EP3 SUBTYPE,SOLUBLE CYTOCHROME B562","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",4,"PRO A  44;MET A 144;GLY A 111;VAL A  49","None","1.38A","6ak3A-2wuqA:undetectable","6ak3A-2wuqA:15.60"],["6B5Y_B_9F2B400_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",7,"SER A  47;SER A 109;ARG A 239;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.49A","6b5yB-2wuqA:29.0","6b5yB-2wuqA:14.55"],["6B5Y_D_9F2D400_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",7,"SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256;THR A 257;GLU A 295","None","0.69A","6b5yD-2wuqA:28.8","6b5yD-2wuqA:14.55"],["6B68_B_9F2B301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.28A","6b68B-2wuqA:29.0","6b68B-2wuqA:14.55"],["6B68_D_9F2D400_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",7,"SER A  47;SER A 109;ARG A 239;LYS A 254;GLY A 256;THR A 257;GLU A 295","None","0.57A","6b68D-2wuqA:29.0","6b68D-2wuqA:14.55"],["6B69_B_9F2B301_1","BETA-LACTAMASE;BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.25A","6b69A-2wuqA:29.0;6b69B-2wuqA:29.0","6b69A-2wuqA:14.55;6b69B-2wuqA:14.55"],["6B69_D_9F2D301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",8,"SER A  47;SER A 109;ARG A 239;LYS A 254;THR A 255;GLY A 256;THR A 257;GLU A 295","None","0.47A","6b69D-2wuqA:28.9","6b69D-2wuqA:14.55"],["6B6A_B_9F2B301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",7,"SER A  47;SER A 109;ARG A 239;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.40A","6b6aB-2wuqA:29.0","6b6aB-2wuqA:14.55"],["6B6A_D_9F2D301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",8,"SER A  47;SER A 109;ARG A 239;LYS A 254;THR A 255;GLY A 256;THR A 257;GLU A 295","None","0.54A","6b6aD-2wuqA:28.9","6b6aD-2wuqA:14.55"],["6B6C_A_9F2A301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",7,"SER A  47;SER A 109;ARG A 239;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.48A","6b6cA-2wuqA:29.0","6b6cA-2wuqA:14.55"],["6B6D_A_9F2A302_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.47A","6b6dA-2wuqA:14.2","6b6dA-2wuqA:14.55"],["6B6E_A_9F2A302_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",7,"SER A  47;SER A 109;ARG A 239;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.46A","6b6eA-2wuqA:28.9","6b6eA-2wuqA:14.55"],["6B6F_A_9F2A301_1","BETA-LACTAMASE","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",6,"SER A  47;SER A 109;LYS A 254;THR A 255;GLY A 256;THR A 257","None","0.53A","6b6fA-2wuqA:28.7","6b6fA-2wuqA:14.55"],["6MN8_A_HFGA603_0","UNCHARACTERIZED PROTEIN","2wuq","BETA-LACTAMASE REGULATORY PROTEIN BLAB","Streptomyces cacaoi",5,"LEU A 198;VAL A 130;PRO A  52;SER A 109;GLY A 111","None","1.34A","6mn8A-2wuqA:undetectable","6mn8A-2wuqA:19.73"]]