SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wuy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 2wuy POLYHEDRIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 11 ILE A 153
LEU A  85
HIS A 139
GLY A 211
LEU A 222
 None
 1.32A 1kyvA-2wuyA:
undetectable
1kyvB-2wuyA:
undetectable		 1kyvA-2wuyA:
20.87
1kyvB-2wuyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 2wuy POLYHEDRIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		4 / 5 PRO A 149
HIS A 139
LEU A  71
TYR A  95
 None
 1.48A 5igjA-2wuyA:
undetectable		 5igjA-2wuyA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_B_PFLB410_1
(PROTON-GATED ION
CHANNEL)		 2wuy POLYHEDRIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 9 TYR A 209
ILE A 207
VAL A  87
TYR A 167
ILE A 169
 None
 1.40A 5mvnB-2wuyA:
undetectable		 5mvnB-2wuyA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_C_PFLC407_1
(PROTON-GATED ION
CHANNEL)		 2wuy POLYHEDRIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 9 TYR A 209
ILE A 207
VAL A  87
TYR A 167
ILE A 169
 None
 1.40A 5mvnC-2wuyA:
0.0		 5mvnC-2wuyA:
17.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVN_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 2wuy POLYHEDRIN
(Autographa
californica
multiple
nucleopolyhedrov
irus) 		5 / 10 TYR A 209
ILE A 207
VAL A  87
TYR A 167
ILE A 169
 None
 1.39A 5mvnD-2wuyA:
undetectable		 5mvnD-2wuyA:
17.03