SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wvi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CZH_A_D2VA602_2 (CYTOCHROME P450 2R1)	2wvi	MITOTIC CHECKPOINT SERINE/THREONINE-PRO TEIN KINASE BUB1 BETA (Homo sapiens)	3 / 3	LEU A 189 GLU A 177 ILE A 174	None	0.56A	3czhA-2wviA: undetectable	3czhA-2wviA: 14.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ETE_C_H3PC552_1 (GLUTAMATE DEHYDROGENASE)	2wvi	MITOTIC CHECKPOINT SERINE/THREONINE-PRO TEIN KINASE BUB1 BETA (Homo sapiens)	3 / 3	TYR A 116 TYR A 141 GLY A 111	None	0.65A	3eteB-2wviA: undetectable 3eteD-2wviA: undetectable 3eteF-2wviA: undetectable	3eteB-2wviA: 15.86 3eteD-2wviA: 15.86 3eteF-2wviA: 15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCN_B_CHDB2_0 (FERROCHELATASE, MITOCHONDRIAL)	2wvi	MITOTIC CHECKPOINT SERINE/THREONINE-PRO TEIN KINASE BUB1 BETA (Homo sapiens)	3 / 3	LEU A 124 LEU A 102 ARG A 104	None	0.74A	3hcnB-2wviA: undetectable	3hcnB-2wviA: 20.38