SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wvw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMY_A_AZMA400_1
(MURINE CARBONIC
ANHYDRASE V)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		5 / 11 VAL I  89
LEU I  85
LEU I  14
THR I  10
THR I  13
 None
 1.10A 1dmyA-2wvwI:
undetectable		 1dmyA-2wvwI:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_2
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		4 / 4 THR I  19
LEU I  23
VAL I  26
LEU I  30
 None
 0.65A 1fbmD-2wvwI:
undetectable		 1fbmD-2wvwI:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FBM_B_RTLB951_3
(PROTEIN (CARTILAGE
OLIGOMERIC MATRIX
PROTEIN))		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		4 / 5 THR I  19
LEU I  23
VAL I  26
LEU I  30
 None
 0.85A 1fbmE-2wvwI:
undetectable		 1fbmE-2wvwI:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		5 / 12 LEU I  85
VAL I  89
LEU I  14
THR I  10
THR I  13
 None
 0.87A 2aw1A-2wvwI:
undetectable		 2aw1A-2wvwI:
24.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		4 / 7 PHE I  60
ARG I  69
MET I  71
THR I  72
 None
 1.00A 3ag2N-2wvwI:
undetectable
3ag2W-2wvwI:
undetectable		 3ag2N-2wvwI:
13.93
3ag2W-2wvwI:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		4 / 7 PHE I  60
ARG I  69
MET I  71
THR I  72
 None
 1.05A 3ag4N-2wvwI:
undetectable
3ag4W-2wvwI:
undetectable		 3ag4N-2wvwI:
13.93
3ag4W-2wvwI:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		5 / 10 LEU I  85
VAL I  89
LEU I  14
THR I  10
THR I  13
 None
 0.84A 4e3hA-2wvwI:
undetectable		 4e3hA-2wvwI:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K13_A_ETSA304_1
(CARBONIC ANHYDRASE 2)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		5 / 12 LEU I  85
VAL I  89
LEU I  14
THR I  10
THR I  13
 None
 0.86A 4k13A-2wvwI:
undetectable		 4k13A-2wvwI:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2W_A_ETSA302_1
(CARBONIC ANHYDRASE 2)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		5 / 12 LEU I  85
VAL I  89
LEU I  14
THR I  10
THR I  13
 None
 0.88A 4m2wA-2wvwI:
undetectable		 4m2wA-2wvwI:
23.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_C_NVPC901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		4 / 8 LEU I  59
VAL I  26
TRP I  40
TYR I  55
 None
 1.11A 4pwdC-2wvwI:
undetectable		 4pwdC-2wvwI:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOP_D_HQED503_1
(CATALASE)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		5 / 9 ILE I  77
LEU I  18
GLN I  21
TYR I  17
LEU I  85
 None
 1.23A 4qopD-2wvwI:
undetectable		 4qopD-2wvwI:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		4 / 7 ALA I  22
THR I  19
TYR I  20
VAL I  26
 None
 0.97A 6cduA-2wvwI:
undetectable
6cduE-2wvwI:
undetectable		 6cduA-2wvwI:
18.38
6cduE-2wvwI:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		4 / 8 VAL I  26
ILE I  70
THR I  19
TYR I  20
 None
 1.06A 6cduG-2wvwI:
undetectable
6cduH-2wvwI:
undetectable		 6cduG-2wvwI:
18.38
6cduH-2wvwI:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2wvw RBCX PROTEIN
(Anabaena
sp.
CA
=
ATCC
33047) 		4 / 7 VAL I  26
ALA I  22
THR I  19
TYR I  20
 None
 0.93A 6cduH-2wvwI:
undetectable
6cduI-2wvwI:
undetectable		 6cduH-2wvwI:
18.38
6cduI-2wvwI:
18.38