SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wws'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NXU_A_RITA600_2
(CYTOCHROME P450 3A4)		 2wws COAT PROTEIN
(Physalis
mottle
virus) 		4 / 7 ILE A 174
LEU A  94
THR A 128
THR A  48
 None
 1.10A 3nxuA-2wwsA:
undetectable		 3nxuA-2wwsA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE3_A_CL6A502_1
(CYTOCHROME P-450)		 2wws COAT PROTEIN
(Physalis
mottle
virus) 		4 / 5 LEU A 154
ALA A  50
THR A  48
VAL A  92
 None
 0.97A 4xe3A-2wwsA:
undetectable		 4xe3A-2wwsA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIW_A_OAQA302_0
(SULFOTRANSFERASE)		 2wws COAT PROTEIN
(Physalis
mottle
virus) 		5 / 12 ILE A  60
LEU A 154
LEU A  63
PHE A  38
LEU A  34
 None
 0.89A 5tiwA-2wwsA:
undetectable		 5tiwA-2wwsA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B54_A_OAQA302_0
(SULFOTRANSFERASE)		 2wws COAT PROTEIN
(Physalis
mottle
virus) 		5 / 12 ILE A  60
LEU A 154
LEU A  63
PHE A  38
LEU A  34
 None
 0.90A 6b54A-2wwsA:
undetectable		 6b54A-2wwsA:
23.19