SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wwv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IVU_A_ZD6A3015_1
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE RECEPTOR RET
PRECURSOR)		 2wwv N,N'-DIACETYLCHITOBI
OSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIA COMPONENT
(Escherichia
coli) 		3 / 3 ALA A  87
GLY A  16
SER A  44
 None
 0.59A 2ivuA-2wwvA:
undetectable		 2ivuA-2wwvA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WDM_B_ADNB301_1
(4-PHOSPHOPANTOATE--B
ETA-ALANINE LIGASE)		 2wwv N,N'-DIACETYLCHITOBI
OSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		5 / 10 GLY D  91
LEU D  55
LEU D  19
LEU D  83
ILE D  79
 None
 1.15A 3wdmB-2wwvD:
undetectable		 3wdmB-2wwvD:
18.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OU1_A_BEZA302_0
(RETRO-ALDOLASE,
DESIGN RA114)		 2wwv N,N'-DIACETYLCHITOBI
OSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		4 / 8 ILE D   6
LYS D   3
ILE D  36
ALA D  27
 None
 0.95A 4ou1A-2wwvD:
undetectable		 4ou1A-2wwvD:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2wwv N,N'-DIACETYLCHITOBI
OSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		5 / 12 ALA D  95
ILE D   6
LEU D  19
MET D  23
GLY D  89
 None
 1.02A 4r38A-2wwvD:
undetectable		 4r38A-2wwvD:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2wwv N,N'-DIACETYLCHITOBI
OSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		5 / 12 ALA D  95
ILE D   6
LEU D  19
MET D  23
GLY D  89
 None
 1.02A 4r38C-2wwvD:
undetectable		 4r38C-2wwvD:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_D_RBFD201_1
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 2wwv N,N'-DIACETYLCHITOBI
OSE-SPECIFIC
PHOSPHOTRANSFERASE
ENZYME IIB COMPONENT
(Escherichia
coli) 		5 / 12 ALA D  95
ILE D   6
LEU D  19
MET D  23
GLY D  89
 None
 1.04A 4r38D-2wwvD:
undetectable		 4r38D-2wwvD:
19.29