SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wyx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1GHM_A_CEDA1_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	6 / 12	SER A 70 LYS A 73 SER A 130 ASN A 132 LYS A 234 GLY A 236	None	0.30A	1ghmA-2wyxA: 37.9	1ghmA-2wyxA: 36.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1I2W_A_CFXA1300_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	SER A 70 LYS A 73 ASN A 104 SER A 130 ASN A 132 THR A 216 LYS A 234 GLY A 236	None	0.32A	1i2wA-2wyxA: 40.9	1i2wA-2wyxA: 41.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1I2W_A_CFXA1300_2 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 5	TYR A 105 PRO A 167 LEU A 169 THR A 235	None	0.61A	1i2wA-2wyxA: 40.9	1i2wA-2wyxA: 41.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1I2W_B_CFXB2300_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	SER A 70 LYS A 73 ASN A 104 SER A 130 ASN A 132 THR A 216 GLY A 236	None	0.33A	1i2wB-2wyxA: 41.1	1i2wB-2wyxA: 41.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RUK_H_BEZH601_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 8	ASN A 132 TYR A 105 GLY A 238 GLY A 236	None	0.87A	1rukH-2wyxA: undetectable 1rukL-2wyxA: undetectable	1rukH-2wyxA: 23.48 1rukL-2wyxA: 21.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YMX_A_CFXA1001_1 (BETA-LACTAMASE CTX-M-9)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	11 / 12	SER A 70 LYS A 73 ASN A 104 SER A 130 ASN A 132 ASN A 170 THR A 216 LYS A 234 GLY A 236 GLY A 238 ASP A 240	None	0.48A	1ymxA-2wyxA: 46.1	1ymxA-2wyxA: 83.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YMX_A_CFXA1001_2 (BETA-LACTAMASE CTX-M-9)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 5	CYH A 69 TYR A 105 PRO A 167 THR A 235 SER A 237	None	0.77A	1ymxA-2wyxA: 46.1	1ymxA-2wyxA: 83.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YMX_B_CFXB1002_1 (BETA-LACTAMASE CTX-M-9)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	11 / 12	SER A 70 LYS A 73 ASN A 104 SER A 130 ASN A 132 ASN A 170 LYS A 234 GLY A 236 SER A 237 GLY A 238 ASP A 240	None	0.48A	1ymxB-2wyxA: 46.1	1ymxB-2wyxA: 83.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YMX_B_CFXB1002_2 (BETA-LACTAMASE CTX-M-9)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 5	CYH A 69 TYR A 105 PRO A 167 THR A 216 THR A 235	None	0.70A	1ymxB-2wyxA: 46.1	1ymxB-2wyxA: 83.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F16_2_BO221405_1 (PROTEASOME COMPONENT PRE3)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 11	THR A 244 THR A 266 SER A 237 GLY A 238 ALA A 172	None	1.23A	2f162-2wyxA: undetectable	2f162-2wyxA: 23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2F16_N_BO2N1404_1 (PROTEASOME COMPONENT PRE3)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 11	THR A 244 THR A 266 SER A 237 GLY A 238 ALA A 172	None	1.23A	2f16N-2wyxA: undetectable	2f16N-2wyxA: 23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_F_TACF3888_1 (ELONGATION FACTOR EF-TU)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 7	THR A 189 ASP A 157 VAL A 148 LEU A 127	None	1.03A	2hdnE-2wyxA: undetectable 2hdnF-2wyxA: undetectable 2hdnH-2wyxA: undetectable	2hdnE-2wyxA: 11.30 2hdnF-2wyxA: 20.65 2hdnH-2wyxA: 20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HDN_H_TACH4888_1 (ELONGATION FACTOR EF-TU)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 7	VAL A 148 LEU A 127 THR A 189 ASP A 157	None	1.06A	2hdnF-2wyxA: undetectable 2hdnG-2wyxA: undetectable 2hdnH-2wyxA: undetectable	2hdnF-2wyxA: 20.65 2hdnG-2wyxA: 11.30 2hdnH-2wyxA: 20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_B_2FAB500_1 (ADENOSYLHOMOCYSTEINA SE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	THR A 194 ASP A 246 LEU A 127 LEU A 211 GLY A 232	None	1.47A	2zj0B-2wyxA: undetectable	2zj0B-2wyxA: 20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZJ0_C_2FAC500_1 (ADENOSYLHOMOCYSTEINA SE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	THR A 194 ASP A 246 LEU A 127 LEU A 211 GLY A 232	None	1.44A	2zj0C-2wyxA: undetectable	2zj0C-2wyxA: 20.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2ZQ9_A_CLSA11_1 (BETA-LACTAMASE TOHO-1)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 4	GLU A 273 ARG A 275 ASN A 276 ASP A 277	None	0.37A	2zq9A-2wyxA: 47.7	2zq9A-2wyxA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZW9_B_SAMB801_1 (LEUCINE CARBOXYL METHYLTRANSFERASE 2)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 8	ILE A 247 SER A 130 TYR A 264 SER A 72	None	0.96A	2zw9B-2wyxA: undetectable	2zw9B-2wyxA: 15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ELZ_A_CHDA150_0 (ILEAL BILE ACID-BINDING PROTEIN)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	THR A 263 VAL A 46 VAL A 74 LEU A 193 THR A 194	None	1.39A	3elzA-2wyxA: undetectable	3elzA-2wyxA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM3_B_478B200_2 (PROTEASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 10	LEU A 259 ASP A 233 VAL A 231 GLY A 224 ILE A 250	None	0.96A	3em3B-2wyxA: undetectable	3em3B-2wyxA: 18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ERD_A_DESA600_1 (ESTROGEN RECEPTOR ALPHA)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	ALA A 77 LEU A 211 LEU A 127 MET A 186 LEU A 193	None	1.16A	3erdA-2wyxA: undetectable	3erdA-2wyxA: 22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ERD_B_DESB800_1 (ESTROGEN RECEPTOR ALPHA)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 10	ALA A 77 LEU A 211 LEU A 127 MET A 186 LEU A 193	None	1.12A	3erdB-2wyxA: undetectable	3erdB-2wyxA: 22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3H5G_B_LEIB16_0 (COIL SER L16D-PEN)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 5	LEU A 199 GLN A 83 LEU A 81 GLU A 85	None	1.10A	3h5gA-2wyxA: undetectable 3h5gB-2wyxA: undetectable	3h5gA-2wyxA: 12.50 3h5gB-2wyxA: 12.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HLW_A_CE3A301_1 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	GLY A 236 ASN A 104 TYR A 105 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 238	None	1.31A	3hlwA-2wyxA: 46.0	3hlwA-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HLW_A_CE3A301_1 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	11 / 12	LYS A 73 ASN A 104 TYR A 105 SER A 130 ASN A 132 ASN A 170 THR A 216 LYS A 234 GLY A 236 SER A 237 GLY A 238	None	0.41A	3hlwA-2wyxA: 46.0	3hlwA-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HLW_A_CE3A301_2 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 4	CYH A 69 PRO A 167 THR A 235 ASP A 240	None	0.56A	3hlwA-2wyxA: 46.0	3hlwA-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HLW_B_CE3B302_1 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	11 / 12	ASN A 104 TYR A 105 SER A 130 ASN A 132 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 SER A 237 GLY A 238	None	0.40A	3hlwB-2wyxA: 46.0	3hlwB-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HLW_B_CE3B302_1 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	GLY A 236 ASN A 104 TYR A 105 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 238	None	1.33A	3hlwB-2wyxA: 46.0	3hlwB-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HLW_B_CE3B302_2 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	3 / 3	CYH A 69 PRO A 167 ASP A 240	None	0.61A	3hlwB-2wyxA: 46.0	3hlwB-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HUO_A_PNNA300_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	CYH A 69 GLY A 236 ASN A 104 ASN A 170 LYS A 234 GLY A 238 ASP A 240	None	1.41A	3huoA-2wyxA: 46.1	3huoA-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HUO_A_PNNA300_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	11 / 12	CYH A 69 LYS A 73 ASN A 104 ASN A 132 ASN A 170 LYS A 234 THR A 235 GLY A 236 SER A 237 GLY A 238 ASP A 240	None	0.44A	3huoA-2wyxA: 46.1	3huoA-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HUO_A_PNNA302_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 6	THR A 51 LEU A 195 GLY A 196 ALA A 257 PRO A 258	None	0.34A	3huoA-2wyxA: 46.1	3huoA-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HUO_B_PNNB301_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	CYH A 69 GLY A 236 ASN A 104 ASN A 170 LYS A 234 GLY A 238 ASP A 240	None	1.40A	3huoB-2wyxA: 46.1	3huoB-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HUO_B_PNNB301_0 (CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	10 / 12	CYH A 69 LYS A 73 ASN A 104 ASN A 132 ASN A 170 LYS A 234 GLY A 236 SER A 237 GLY A 238 ASP A 240	None	0.43A	3huoB-2wyxA: 46.1	3huoB-2wyxA: 83.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MG0_N_BO2N1404_1 (PROTEASOME COMPONENT PRE3)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 11	THR A 244 THR A 266 SER A 237 GLY A 238 ALA A 172	None	1.21A	3mg0N-2wyxA: undetectable	3mg0N-2wyxA: 23.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NY4_A_SMXA308_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	9 / 12	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238 ASP A 240	None	0.60A	3ny4A-2wyxA: 40.1	3ny4A-2wyxA: 45.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3NY4_A_SMXA310_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 8	LEU A 195 ALA A 205 TRP A 251 PRO A 258	None	0.91A	3ny4A-2wyxA: 40.1	3ny4A-2wyxA: 45.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OZW_A_KKKA413_1 (FLAVOHEMOGLOBIN)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 8	ILE A 285 GLN A 32 ALA A 35 LEU A 36	None	0.60A	3ozwA-2wyxA: undetectable	3ozwA-2wyxA: 20.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3Q07_A_WPPA300_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	GLY A 236 ASN A 104 SER A 130 ASN A 170 LYS A 234 GLY A 238 ASP A 240	None	1.45A	3q07A-2wyxA: 45.7	3q07A-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3Q07_A_WPPA300_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	11 / 12	LYS A 73 ASN A 104 SER A 130 ASN A 132 THR A 168 ASN A 170 LYS A 234 GLY A 236 SER A 237 GLY A 238 ASP A 240	None	0.54A	3q07A-2wyxA: 45.7	3q07A-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3Q07_A_WPPA300_2 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 5	CYH A 69 TYR A 105 PRO A 167 THR A 171 THR A 235	None	0.57A	3q07A-2wyxA: 45.7	3q07A-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3Q07_B_WPPB400_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	GLY A 236 ASN A 104 SER A 130 ASN A 170 LYS A 234 GLY A 238 ASP A 240	None	1.46A	3q07B-2wyxA: 46.0	3q07B-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3Q07_B_WPPB400_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	11 / 12	LYS A 73 ASN A 104 SER A 130 ASN A 132 THR A 168 ASN A 170 LYS A 234 GLY A 236 SER A 237 GLY A 238 ASP A 240	None	0.49A	3q07B-2wyxA: 46.0	3q07B-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3Q07_B_WPPB400_2 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 5	CYH A 69 TYR A 105 PRO A 167 THR A 171 THR A 235	None	0.62A	3q07B-2wyxA: 46.0	3q07B-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SH8_A_CEDA1_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	SER A 70 ASN A 104 TYR A 105 SER A 130 ASN A 132 LYS A 234 THR A 235 GLY A 236	None	0.53A	3sh8A-2wyxA: 39.9	3sh8A-2wyxA: 41.54
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3SH8_B_CEDB1_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	SER A 70 LYS A 73 ASN A 104 SER A 130 ASN A 132 LYS A 234 GLY A 236	None	0.39A	3sh8B-2wyxA: 39.6	3sh8B-2wyxA: 41.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UT5_D_LOCD502_1 (TUBULIN BETA CHAIN)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	LEU A 119 ASN A 136 ALA A 109 ALA A 125 ILE A 97	None	1.15A	3ut5D-2wyxA: undetectable	3ut5D-2wyxA: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VAS_B_ADNB401_2 (PUTATIVE ADENOSINE KINASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 5	LEU A 155 ALA A 78 MET A 186 THR A 189	None	1.40A	3vasB-2wyxA: undetectable	3vasB-2wyxA: 21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4EUZ_A_MEMA401_1 (CARBAPENEM-HYDROLIZI NG BETA-LACTAMASE SFC-1)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	LYS A 73 SER A 130 ASN A 132 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236	None	0.41A	4euzA-2wyxA: 41.9	4euzA-2wyxA: 47.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4FH2_A_0RNA303_1 (BETA-LACTAMASE SHV-1)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	6 / 10	TYR A 105 SER A 130 ASN A 132 LYS A 234 THR A 235 GLY A 236	None	0.58A	4fh2A-2wyxA: 35.3	4fh2A-2wyxA: 41.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IKJ_B_SUZB201_1 (TRANSTHYRETIN)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 8	SER A 220 SER A 218 LEU A 211 ALA A 248	None	0.99A	4ikjA-2wyxA: undetectable 4ikjB-2wyxA: undetectable	4ikjA-2wyxA: 18.88 4ikjB-2wyxA: 18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_B_SASB804_1 (SEPIAPTERIN REDUCTASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	LEU A 122 GLN A 83 ALA A 79 GLY A 143 LEU A 142	None	1.05A	4j7xB-2wyxA: undetectable	4j7xB-2wyxA: 21.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4N9K_A_CEDA301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	9 / 12	SER A 70 ASN A 104 TYR A 105 SER A 130 ASN A 132 ASN A 170 LYS A 234 THR A 235 GLY A 236	None	0.51A	4n9kA-2wyxA: 41.6	4n9kA-2wyxA: 41.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4N9K_B_CEDB301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	SER A 70 ASN A 104 SER A 130 ASN A 132 ASN A 170 LYS A 234 THR A 235 GLY A 236	None	0.51A	4n9kB-2wyxA: 41.4	4n9kB-2wyxA: 41.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM5_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	10 / 12	ASN A 104 TYR A 105 ASN A 132 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 SER A 237 GLY A 238	None	0.48A	4pm5A-2wyxA: 46.0	4pm5A-2wyxA: 83.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM5_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	9 / 12	ASN A 104 TYR A 105 SER A 130 ASN A 132 LYS A 234 THR A 235 GLY A 236 SER A 237 GLY A 238	None	0.68A	4pm5A-2wyxA: 46.0	4pm5A-2wyxA: 83.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM5_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	GLY A 236 ASN A 104 TYR A 105 ASN A 170 THR A 216 LYS A 234 GLY A 238	None	1.44A	4pm5A-2wyxA: 46.0	4pm5A-2wyxA: 83.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM5_A_CE3A301_2 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	3 / 3	CYH A 69 PRO A 167 ASP A 240	None	0.55A	4pm5A-2wyxA: 46.0	4pm5A-2wyxA: 83.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM7_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	GLY A 236 ASN A 104 TYR A 105 ASN A 170 THR A 216 LYS A 234 GLY A 238	None	1.43A	4pm7A-2wyxA: 46.0	4pm7A-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM7_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	9 / 12	LYS A 73 ASN A 104 TYR A 105 ASN A 132 ASN A 170 THR A 216 LYS A 234 GLY A 236 GLY A 238	None	0.48A	4pm7A-2wyxA: 46.0	4pm7A-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM7_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	LYS A 73 ASN A 104 TYR A 105 SER A 130 ASN A 132 LYS A 234 GLY A 236 GLY A 238	None	0.69A	4pm7A-2wyxA: 46.0	4pm7A-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM7_A_CE3A301_2 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 4	CYH A 69 PRO A 167 THR A 235 ASP A 240	None	0.64A	4pm7A-2wyxA: 46.0	4pm7A-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM9_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	9 / 12	ASN A 104 TYR A 105 ASN A 132 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238	None	0.47A	4pm9A-2wyxA: 46.0	4pm9A-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM9_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	ASN A 104 TYR A 105 SER A 130 ASN A 132 LYS A 234 THR A 235 GLY A 236 GLY A 238	None	0.68A	4pm9A-2wyxA: 46.0	4pm9A-2wyxA: 83.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4PM9_A_CE3A301_1 (BETA-LACTAMASE CTX-M-14)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	GLY A 236 ASN A 104 TYR A 105 ASN A 170 THR A 216 LYS A 234 GLY A 238	None	1.43A	4pm9A-2wyxA: 46.0	4pm9A-2wyxA: 83.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1I_D_LOCD502_1 (TUBULIN BETA CHAIN)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	LEU A 119 ASN A 136 ALA A 109 ALA A 125 ILE A 97	None	1.11A	4x1iD-2wyxA: undetectable	4x1iD-2wyxA: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1K_D_LOCD502_2 (TUBULIN BETA CHAIN)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	LEU A 119 ASN A 136 ALA A 109 ALA A 125 ILE A 97	None	1.10A	4x1kD-2wyxA: undetectable	4x1kD-2wyxA: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X20_B_LOCB502_1 (TUBULIN BETA CHAIN)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	LEU A 119 ASN A 136 ALA A 109 ALA A 125 ILE A 97	None	1.04A	4x20B-2wyxA: undetectable	4x20B-2wyxA: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_D_29SD601_1 (ESTROGEN RECEPTOR)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	ALA A 283 LEU A 279 LEU A 261 LEU A 259 LEU A 33	None	1.27A	4xi3D-2wyxA: undetectable	4xi3D-2wyxA: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZN7_B_DESB600_1 (ESTROGEN RECEPTOR)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 11	ALA A 77 LEU A 211 LEU A 127 MET A 186 LEU A 193	None	1.18A	4zn7B-2wyxA: undetectable	4zn7B-2wyxA: 21.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5GHY_A_CEDA301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	6 / 12	SER A 70 SER A 130 ASN A 132 ASN A 170 LYS A 234 GLY A 236	None	0.57A	5ghyA-2wyxA: 41.2	5ghyA-2wyxA: 41.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5GHY_B_CEDB301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	6 / 12	SER A 70 SER A 130 ASN A 132 ASN A 170 LYS A 234 GLY A 236	None	0.56A	5ghyB-2wyxA: 41.1	5ghyB-2wyxA: 41.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5GHZ_A_CEDA301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 11	SER A 70 TYR A 105 SER A 130 ASN A 132 ASN A 170 LYS A 234 THR A 235 GLY A 236	None	0.55A	5ghzA-2wyxA: 41.3	5ghzA-2wyxA: 41.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5GHZ_B_CEDB301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 10	SER A 70 TYR A 105 SER A 130 ASN A 132 ASN A 170 LYS A 234 THR A 235 GLY A 236	None	0.54A	5ghzB-2wyxA: 41.3	5ghzB-2wyxA: 41.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	5KMW_A_PNNA305_0 (BETA-LACTAMASE TOHO-1)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 4	ASN A 104 PRO A 167 ASN A 170 ASP A 240	None	0.40A	5kmwA-2wyxA: 48.0	5kmwA-2wyxA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_B_BO2B201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	THR A 244 THR A 266 SER A 237 GLY A 238 ALA A 172	None	1.22A	5l5zV-2wyxA: undetectable 5l5zb-2wyxA: undetectable	5l5zV-2wyxA: 21.29 5l5zb-2wyxA: 23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L5Z_N_BO2N201_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-1)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	THR A 244 THR A 266 SER A 237 GLY A 238 ALA A 172	None	1.22A	5l5zH-2wyxA: undetectable 5l5zN-2wyxA: undetectable	5l5zH-2wyxA: 21.29 5l5zN-2wyxA: 23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF3_B_BO2B305_1 (PROTEASOME SUBUNIT BETA TYPE-6)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	THR A 244 THR A 266 SER A 237 GLY A 238 ALA A 172	None	1.22A	5lf3b-2wyxA: undetectable	5lf3b-2wyxA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5LF3_N_BO2N304_1 (PROTEASOME SUBUNIT BETA TYPE-6)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 12	THR A 244 THR A 266 SER A 237 GLY A 238 ALA A 172	None	1.21A	5lf3N-2wyxA: undetectable	5lf3N-2wyxA: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M0I_B_ACTB303_0 (SWI5-DEPENDENT HO EXPRESSION PROTEIN 2)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 5	VAL A 74 ASN A 214 ASP A 233 LEU A 211	None	1.33A	5m0iB-2wyxA: undetectable	5m0iB-2wyxA: 24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_A_9F2A302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 9	PRO A 107 TYR A 129 THR A 215 THR A 216 ASP A 240	None	0.54A	6b5yA-2wyxA: 40.4 6b5yB-2wyxA: 40.5	6b5yA-2wyxA: 18.53 6b5yB-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_B_9F2B400_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	10 / 12	CYH A 69 SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238 ASP A 240	None	0.49A	6b5yB-2wyxA: 40.5	6b5yB-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_C_9F2C302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 10	PRO A 107 TYR A 129 THR A 215 THR A 216 ASP A 240	None	0.64A	6b5yC-2wyxA: 40.6 6b5yD-2wyxA: 40.6	6b5yC-2wyxA: 18.53 6b5yD-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_D_9F2D400_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	9 / 12	CYH A 69 SER A 70 SER A 130 ASN A 170 THR A 216 THR A 235 GLY A 236 GLY A 238 ASP A 240	None	0.44A	6b5yD-2wyxA: 40.6	6b5yD-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B5Y_D_9F2D400_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	9 / 12	CYH A 69 SER A 70 SER A 130 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238 ASP A 240	None	0.48A	6b5yD-2wyxA: 40.6	6b5yD-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_A_9F2A302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 9	PRO A 107 TYR A 129 THR A 215 THR A 216 ASP A 240	None	0.52A	6b68A-2wyxA: 40.8 6b68B-2wyxA: 40.7	6b68A-2wyxA: 18.53 6b68B-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_B_9F2B301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	10 / 12	CYH A 69 SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238 ASP A 240	None	0.42A	6b68B-2wyxA: 40.7	6b68B-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_C_9F2C302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 10	PRO A 107 TYR A 129 THR A 215 THR A 216 ASP A 240	None	0.61A	6b68C-2wyxA: 40.7 6b68D-2wyxA: 40.6	6b68C-2wyxA: 18.53 6b68D-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B68_D_9F2D400_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 GLY A 236 GLY A 238 ASP A 240	None	0.52A	6b68D-2wyxA: 40.6	6b68D-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_A_9F2A302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 9	PRO A 107 TYR A 129 THR A 215 THR A 216 ASP A 240	None	0.56A	6b69A-2wyxA: 40.6 6b69B-2wyxA: 40.5	6b69A-2wyxA: 18.53 6b69B-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_B_9F2B301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	10 / 12	SER A 70 SER A 130 PRO A 167 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238 ASP A 240	None	0.50A	6b69A-2wyxA: 40.6 6b69B-2wyxA: 40.5	6b69A-2wyxA: 18.53 6b69B-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_C_9F2C302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 9	PRO A 107 TYR A 129 THR A 215 THR A 216 ASP A 240	None	0.54A	6b69C-2wyxA: 40.6 6b69D-2wyxA: 40.5	6b69C-2wyxA: 18.53 6b69D-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B69_D_9F2D301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	9 / 12	CYH A 69 SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238	None	0.36A	6b69D-2wyxA: 40.5	6b69D-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_A_9F2A302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 9	PRO A 107 TYR A 129 THR A 215 THR A 216 ASP A 240	None	0.60A	6b6aA-2wyxA: 40.4 6b6aB-2wyxA: 40.6	6b6aA-2wyxA: 18.53 6b6aB-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_B_9F2B301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	10 / 12	CYH A 69 SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238 ASP A 240	None	0.45A	6b6aB-2wyxA: 40.6	6b6aB-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_C_9F2C302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	5 / 9	PRO A 107 TYR A 129 THR A 215 THR A 216 ASP A 240	None	0.55A	6b6aC-2wyxA: 40.5 6b6aD-2wyxA: 40.6	6b6aC-2wyxA: 18.53 6b6aD-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6A_D_9F2D301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	SER A 70 SER A 130 ASN A 170 LYS A 234 THR A 235 GLY A 236 GLY A 238 ASP A 240	None	0.37A	6b6aD-2wyxA: 40.6	6b6aD-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6C_A_9F2A301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	SER A 70 SER A 130 PRO A 167 ASN A 170 LYS A 234 THR A 235 GLY A 236 GLY A 238	None	0.64A	6b6cA-2wyxA: 40.5	6b6cA-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6D_A_9F2A302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	CYH A 69 SER A 70 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238	None	0.47A	6b6dA-2wyxA: 40.3	6b6dA-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6D_A_9F2A302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	7 / 12	CYH A 69 SER A 70 SER A 130 LYS A 234 THR A 235 GLY A 236 GLY A 238	None	0.56A	6b6dA-2wyxA: 40.3	6b6dA-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6E_A_9F2A302_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	8 / 12	SER A 70 SER A 130 ASN A 170 THR A 216 LYS A 234 THR A 235 GLY A 236 GLY A 238	None	0.41A	6b6eA-2wyxA: 40.5	6b6eA-2wyxA: 18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B6F_A_9F2A301_1 (BETA-LACTAMASE)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	10 / 12	CYH A 69 SER A 70 SER A 130 PRO A 167 ASN A 170 LYS A 234 THR A 235 GLY A 236 GLY A 238 ASP A 240	None	0.65A	6b6fA-2wyxA: 40.2	6b6fA-2wyxA: 18.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6C79_A_CE3A301_1 (BETA-LACTAMASE TOHO-1)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	11 / 12	ASN A 104 TYR A 105 SER A 130 ASN A 132 ASN A 170 THR A 216 LYS A 234 GLY A 236 SER A 237 GLY A 238 ASN A 274	None	0.39A	6c79A-2wyxA: 47.7	6c79A-2wyxA: 98.72
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	6C79_A_CE3A301_2 (BETA-LACTAMASE TOHO-1)	2wyx	BETA-LACTAMSE TOHO-1 (Escherichia coli)	4 / 4	CYH A 69 PRO A 167 THR A 235 ASP A 240	None	0.59A	6c79A-2wyxA: 47.7	6c79A-2wyxA: 98.72

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GHM_A_CEDA1_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",6,"SER A  70;LYS A  73;SER A 130;ASN A 132;LYS A 234;GLY A 236","None","0.30A","1ghmA-2wyxA:37.9","1ghmA-2wyxA:36.92"],["1I2W_A_CFXA1300_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"SER A  70;LYS A  73;ASN A 104;SER A 130;ASN A 132;THR A 216;LYS A 234;GLY A 236","None","0.32A","1i2wA-2wyxA:40.9","1i2wA-2wyxA:41.30"],["1I2W_A_CFXA1300_2","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"TYR A 105;PRO A 167;LEU A 169;THR A 235","None","0.61A","1i2wA-2wyxA:40.9","1i2wA-2wyxA:41.30"],["1I2W_B_CFXB2300_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"SER A  70;LYS A  73;ASN A 104;SER A 130;ASN A 132;THR A 216;GLY A 236","None","0.33A","1i2wB-2wyxA:41.1","1i2wB-2wyxA:41.30"],["1RUK_H_BEZH601_0","IMMUNOGLOBULIN IGG2A, HEAVY CHAIN;IMMUNOGLOBULIN IGG2A, LIGHT CHAIN","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"ASN A 132;TYR A 105;GLY A 238;GLY A 236","None","0.87A","1rukH-2wyxA:undetectable;1rukL-2wyxA:undetectable","1rukH-2wyxA:23.48;1rukL-2wyxA:21.89"],["1YMX_A_CFXA1001_1","BETA-LACTAMASE CTX-M-9","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",11,"SER A  70;LYS A  73;ASN A 104;SER A 130;ASN A 132;ASN A 170;THR A 216;LYS A 234;GLY A 236;GLY A 238;ASP A 240","None","0.48A","1ymxA-2wyxA:46.1","1ymxA-2wyxA:83.98"],["1YMX_A_CFXA1001_2","BETA-LACTAMASE CTX-M-9","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"CYH A  69;TYR A 105;PRO A 167;THR A 235;SER A 237","None","0.77A","1ymxA-2wyxA:46.1","1ymxA-2wyxA:83.98"],["1YMX_B_CFXB1002_1","BETA-LACTAMASE CTX-M-9","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",11,"SER A  70;LYS A  73;ASN A 104;SER A 130;ASN A 132;ASN A 170;LYS A 234;GLY A 236;SER A 237;GLY A 238;ASP A 240","None","0.48A","1ymxB-2wyxA:46.1","1ymxB-2wyxA:83.98"],["1YMX_B_CFXB1002_2","BETA-LACTAMASE CTX-M-9","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"CYH A  69;TYR A 105;PRO A 167;THR A 216;THR A 235","None","0.70A","1ymxB-2wyxA:46.1","1ymxB-2wyxA:83.98"],["2F16_2_BO221405_1","PROTEASOME COMPONENT PRE3","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 244;THR A 266;SER A 237;GLY A 238;ALA A 172","None","1.23A","2f162-2wyxA:undetectable","2f162-2wyxA:23.05"],["2F16_N_BO2N1404_1","PROTEASOME COMPONENT PRE3","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 244;THR A 266;SER A 237;GLY A 238;ALA A 172","None","1.23A","2f16N-2wyxA:undetectable","2f16N-2wyxA:23.05"],["2HDN_F_TACF3888_1","ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"THR A 189;ASP A 157;VAL A 148;LEU A 127","None","1.03A","2hdnE-2wyxA:undetectable;2hdnF-2wyxA:undetectable;2hdnH-2wyxA:undetectable","2hdnE-2wyxA:11.30;2hdnF-2wyxA:20.65;2hdnH-2wyxA:20.65"],["2HDN_H_TACH4888_1","ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU;ELONGATION FACTOR EF-TU","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"VAL A 148;LEU A 127;THR A 189;ASP A 157","None","1.06A","2hdnF-2wyxA:undetectable;2hdnG-2wyxA:undetectable;2hdnH-2wyxA:undetectable","2hdnF-2wyxA:20.65;2hdnG-2wyxA:11.30;2hdnH-2wyxA:20.65"],["2ZJ0_B_2FAB500_1","ADENOSYLHOMOCYSTEINASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 194;ASP A 246;LEU A 127;LEU A 211;GLY A 232","None","1.47A","2zj0B-2wyxA:undetectable","2zj0B-2wyxA:20.04"],["2ZJ0_C_2FAC500_1","ADENOSYLHOMOCYSTEINASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 194;ASP A 246;LEU A 127;LEU A 211;GLY A 232","None","1.44A","2zj0C-2wyxA:undetectable","2zj0C-2wyxA:20.04"],["2ZQ9_A_CLSA11_1","BETA-LACTAMASE TOHO-1","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"GLU A 273;ARG A 275;ASN A 276;ASP A 277","None","0.37A","2zq9A-2wyxA:47.7","2zq9A-2wyxA:100.00"],["2ZW9_B_SAMB801_1","LEUCINE CARBOXYL METHYLTRANSFERASE 2","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"ILE A 247;SER A 130;TYR A 264;SER A  72","None","0.96A","2zw9B-2wyxA:undetectable","2zw9B-2wyxA:15.98"],["3ELZ_A_CHDA150_0","ILEAL BILE ACID-BINDING PROTEIN","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 263;VAL A  46;VAL A  74;LEU A 193;THR A 194","None","1.39A","3elzA-2wyxA:undetectable","3elzA-2wyxA:21.69"],["3EM3_B_478B200_2","PROTEASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"LEU A 259;ASP A 233;VAL A 231;GLY A 224;ILE A 250","None","0.96A","3em3B-2wyxA:undetectable","3em3B-2wyxA:18.14"],["3ERD_A_DESA600_1","ESTROGEN RECEPTOR ALPHA","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"ALA A  77;LEU A 211;LEU A 127;MET A 186;LEU A 193","None","1.16A","3erdA-2wyxA:undetectable","3erdA-2wyxA:22.85"],["3ERD_B_DESB800_1","ESTROGEN RECEPTOR ALPHA","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"ALA A  77;LEU A 211;LEU A 127;MET A 186;LEU A 193","None","1.12A","3erdB-2wyxA:undetectable","3erdB-2wyxA:22.85"],["3H5G_B_LEIB16_0","COIL SER L16D-PEN","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"LEU A 199;GLN A  83;LEU A  81;GLU A  85","None","1.10A","3h5gA-2wyxA:undetectable;3h5gB-2wyxA:undetectable","3h5gA-2wyxA:12.50;3h5gB-2wyxA:12.50"],["3HLW_A_CE3A301_1","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"GLY A 236;ASN A 104;TYR A 105;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 238","None","1.31A","3hlwA-2wyxA:46.0","3hlwA-2wyxA:83.59"],["3HLW_A_CE3A301_1","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",11,"LYS A  73;ASN A 104;TYR A 105;SER A 130;ASN A 132;ASN A 170;THR A 216;LYS A 234;GLY A 236;SER A 237;GLY A 238","None","0.41A","3hlwA-2wyxA:46.0","3hlwA-2wyxA:83.59"],["3HLW_A_CE3A301_2","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"CYH A  69;PRO A 167;THR A 235;ASP A 240","None","0.56A","3hlwA-2wyxA:46.0","3hlwA-2wyxA:83.59"],["3HLW_B_CE3B302_1","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",11,"ASN A 104;TYR A 105;SER A 130;ASN A 132;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;SER A 237;GLY A 238","None","0.40A","3hlwB-2wyxA:46.0","3hlwB-2wyxA:83.59"],["3HLW_B_CE3B302_1","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"GLY A 236;ASN A 104;TYR A 105;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 238","None","1.33A","3hlwB-2wyxA:46.0","3hlwB-2wyxA:83.59"],["3HLW_B_CE3B302_2","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",3,"CYH A  69;PRO A 167;ASP A 240","None","0.61A","3hlwB-2wyxA:46.0","3hlwB-2wyxA:83.59"],["3HUO_A_PNNA300_0","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"CYH A  69;GLY A 236;ASN A 104;ASN A 170;LYS A 234;GLY A 238;ASP A 240","None","1.41A","3huoA-2wyxA:46.1","3huoA-2wyxA:83.59"],["3HUO_A_PNNA300_0","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",11,"CYH A  69;LYS A  73;ASN A 104;ASN A 132;ASN A 170;LYS A 234;THR A 235;GLY A 236;SER A 237;GLY A 238;ASP A 240","None","0.44A","3huoA-2wyxA:46.1","3huoA-2wyxA:83.59"],["3HUO_A_PNNA302_0","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A  51;LEU A 195;GLY A 196;ALA A 257;PRO A 258","None","0.34A","3huoA-2wyxA:46.1","3huoA-2wyxA:83.59"],["3HUO_B_PNNB301_0","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"CYH A  69;GLY A 236;ASN A 104;ASN A 170;LYS A 234;GLY A 238;ASP A 240","None","1.40A","3huoB-2wyxA:46.1","3huoB-2wyxA:83.59"],["3HUO_B_PNNB301_0","CTX-M-9 EXTENDED-SPECTRUM BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",10,"CYH A  69;LYS A  73;ASN A 104;ASN A 132;ASN A 170;LYS A 234;GLY A 236;SER A 237;GLY A 238;ASP A 240","None","0.43A","3huoB-2wyxA:46.1","3huoB-2wyxA:83.59"],["3MG0_N_BO2N1404_1","PROTEASOME COMPONENT PRE3","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 244;THR A 266;SER A 237;GLY A 238;ALA A 172","None","1.21A","3mg0N-2wyxA:undetectable","3mg0N-2wyxA:23.05"],["3NY4_A_SMXA308_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",9,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238;ASP A 240","None","0.60A","3ny4A-2wyxA:40.1","3ny4A-2wyxA:45.63"],["3NY4_A_SMXA310_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"LEU A 195;ALA A 205;TRP A 251;PRO A 258","None","0.91A","3ny4A-2wyxA:40.1","3ny4A-2wyxA:45.63"],["3OZW_A_KKKA413_1","FLAVOHEMOGLOBIN","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"ILE A 285;GLN A  32;ALA A  35;LEU A  36","None","0.60A","3ozwA-2wyxA:undetectable","3ozwA-2wyxA:20.69"],["3Q07_A_WPPA300_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"GLY A 236;ASN A 104;SER A 130;ASN A 170;LYS A 234;GLY A 238;ASP A 240","None","1.45A","3q07A-2wyxA:45.7","3q07A-2wyxA:83.59"],["3Q07_A_WPPA300_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",11,"LYS A  73;ASN A 104;SER A 130;ASN A 132;THR A 168;ASN A 170;LYS A 234;GLY A 236;SER A 237;GLY A 238;ASP A 240","None","0.54A","3q07A-2wyxA:45.7","3q07A-2wyxA:83.59"],["3Q07_A_WPPA300_2","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"CYH A  69;TYR A 105;PRO A 167;THR A 171;THR A 235","None","0.57A","3q07A-2wyxA:45.7","3q07A-2wyxA:83.59"],["3Q07_B_WPPB400_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"GLY A 236;ASN A 104;SER A 130;ASN A 170;LYS A 234;GLY A 238;ASP A 240","None","1.46A","3q07B-2wyxA:46.0","3q07B-2wyxA:83.59"],["3Q07_B_WPPB400_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",11,"LYS A  73;ASN A 104;SER A 130;ASN A 132;THR A 168;ASN A 170;LYS A 234;GLY A 236;SER A 237;GLY A 238;ASP A 240","None","0.49A","3q07B-2wyxA:46.0","3q07B-2wyxA:83.59"],["3Q07_B_WPPB400_2","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"CYH A  69;TYR A 105;PRO A 167;THR A 171;THR A 235","None","0.62A","3q07B-2wyxA:46.0","3q07B-2wyxA:83.59"],["3SH8_A_CEDA1_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"SER A  70;ASN A 104;TYR A 105;SER A 130;ASN A 132;LYS A 234;THR A 235;GLY A 236","None","0.53A","3sh8A-2wyxA:39.9","3sh8A-2wyxA:41.54"],["3SH8_B_CEDB1_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"SER A  70;LYS A  73;ASN A 104;SER A 130;ASN A 132;LYS A 234;GLY A 236","None","0.39A","3sh8B-2wyxA:39.6","3sh8B-2wyxA:41.54"],["3UT5_D_LOCD502_1","TUBULIN BETA CHAIN","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"LEU A 119;ASN A 136;ALA A 109;ALA A 125;ILE A  97","None","1.15A","3ut5D-2wyxA:undetectable","3ut5D-2wyxA:22.04"],["3VAS_B_ADNB401_2","PUTATIVE ADENOSINE KINASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"LEU A 155;ALA A  78;MET A 186;THR A 189","None","1.40A","3vasB-2wyxA:undetectable","3vasB-2wyxA:21.90"],["4EUZ_A_MEMA401_1","CARBAPENEM-HYDROLIZING BETA-LACTAMASE SFC-1","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"LYS A  73;SER A 130;ASN A 132;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236","None","0.41A","4euzA-2wyxA:41.9","4euzA-2wyxA:47.35"],["4FH2_A_0RNA303_1","BETA-LACTAMASE SHV-1","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",6,"TYR A 105;SER A 130;ASN A 132;LYS A 234;THR A 235;GLY A 236","None","0.58A","4fh2A-2wyxA:35.3","4fh2A-2wyxA:41.29"],["4IKJ_B_SUZB201_1","TRANSTHYRETIN;TRANSTHYRETIN","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"SER A 220;SER A 218;LEU A 211;ALA A 248","None","0.99A","4ikjA-2wyxA:undetectable;4ikjB-2wyxA:undetectable","4ikjA-2wyxA:18.88;4ikjB-2wyxA:18.88"],["4J7X_B_SASB804_1","SEPIAPTERIN REDUCTASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"LEU A 122;GLN A  83;ALA A  79;GLY A 143;LEU A 142","None","1.05A","4j7xB-2wyxA:undetectable","4j7xB-2wyxA:21.78"],["4N9K_A_CEDA301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",9,"SER A  70;ASN A 104;TYR A 105;SER A 130;ASN A 132;ASN A 170;LYS A 234;THR A 235;GLY A 236","None","0.51A","4n9kA-2wyxA:41.6","4n9kA-2wyxA:41.60"],["4N9K_B_CEDB301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"SER A  70;ASN A 104;SER A 130;ASN A 132;ASN A 170;LYS A 234;THR A 235;GLY A 236","None","0.51A","4n9kB-2wyxA:41.4","4n9kB-2wyxA:41.60"],["4PM5_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",10,"ASN A 104;TYR A 105;ASN A 132;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;SER A 237;GLY A 238","None","0.48A","4pm5A-2wyxA:46.0","4pm5A-2wyxA:83.98"],["4PM5_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",9,"ASN A 104;TYR A 105;SER A 130;ASN A 132;LYS A 234;THR A 235;GLY A 236;SER A 237;GLY A 238","None","0.68A","4pm5A-2wyxA:46.0","4pm5A-2wyxA:83.98"],["4PM5_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"GLY A 236;ASN A 104;TYR A 105;ASN A 170;THR A 216;LYS A 234;GLY A 238","None","1.44A","4pm5A-2wyxA:46.0","4pm5A-2wyxA:83.98"],["4PM5_A_CE3A301_2","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",3,"CYH A  69;PRO A 167;ASP A 240","None","0.55A","4pm5A-2wyxA:46.0","4pm5A-2wyxA:83.98"],["4PM7_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"GLY A 236;ASN A 104;TYR A 105;ASN A 170;THR A 216;LYS A 234;GLY A 238","None","1.43A","4pm7A-2wyxA:46.0","4pm7A-2wyxA:83.59"],["4PM7_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",9,"LYS A  73;ASN A 104;TYR A 105;ASN A 132;ASN A 170;THR A 216;LYS A 234;GLY A 236;GLY A 238","None","0.48A","4pm7A-2wyxA:46.0","4pm7A-2wyxA:83.59"],["4PM7_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"LYS A  73;ASN A 104;TYR A 105;SER A 130;ASN A 132;LYS A 234;GLY A 236;GLY A 238","None","0.69A","4pm7A-2wyxA:46.0","4pm7A-2wyxA:83.59"],["4PM7_A_CE3A301_2","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"CYH A  69;PRO A 167;THR A 235;ASP A 240","None","0.64A","4pm7A-2wyxA:46.0","4pm7A-2wyxA:83.59"],["4PM9_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",9,"ASN A 104;TYR A 105;ASN A 132;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238","None","0.47A","4pm9A-2wyxA:46.0","4pm9A-2wyxA:83.59"],["4PM9_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"ASN A 104;TYR A 105;SER A 130;ASN A 132;LYS A 234;THR A 235;GLY A 236;GLY A 238","None","0.68A","4pm9A-2wyxA:46.0","4pm9A-2wyxA:83.59"],["4PM9_A_CE3A301_1","BETA-LACTAMASE CTX-M-14","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"GLY A 236;ASN A 104;TYR A 105;ASN A 170;THR A 216;LYS A 234;GLY A 238","None","1.43A","4pm9A-2wyxA:46.0","4pm9A-2wyxA:83.59"],["4X1I_D_LOCD502_1","TUBULIN BETA CHAIN","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"LEU A 119;ASN A 136;ALA A 109;ALA A 125;ILE A  97","None","1.11A","4x1iD-2wyxA:undetectable","4x1iD-2wyxA:21.11"],["4X1K_D_LOCD502_2","TUBULIN BETA CHAIN","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"LEU A 119;ASN A 136;ALA A 109;ALA A 125;ILE A  97","None","1.10A","4x1kD-2wyxA:undetectable","4x1kD-2wyxA:21.11"],["4X20_B_LOCB502_1","TUBULIN BETA CHAIN","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"LEU A 119;ASN A 136;ALA A 109;ALA A 125;ILE A  97","None","1.04A","4x20B-2wyxA:undetectable","4x20B-2wyxA:21.11"],["4XI3_D_29SD601_1","ESTROGEN RECEPTOR","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"ALA A 283;LEU A 279;LEU A 261;LEU A 259;LEU A  33","None","1.27A","4xi3D-2wyxA:undetectable","4xi3D-2wyxA:21.75"],["4ZN7_B_DESB600_1","ESTROGEN RECEPTOR","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"ALA A  77;LEU A 211;LEU A 127;MET A 186;LEU A 193","None","1.18A","4zn7B-2wyxA:undetectable","4zn7B-2wyxA:21.38"],["5GHY_A_CEDA301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",6,"SER A  70;SER A 130;ASN A 132;ASN A 170;LYS A 234;GLY A 236","None","0.57A","5ghyA-2wyxA:41.2","5ghyA-2wyxA:41.60"],["5GHY_B_CEDB301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",6,"SER A  70;SER A 130;ASN A 132;ASN A 170;LYS A 234;GLY A 236","None","0.56A","5ghyB-2wyxA:41.1","5ghyB-2wyxA:41.60"],["5GHZ_A_CEDA301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"SER A  70;TYR A 105;SER A 130;ASN A 132;ASN A 170;LYS A 234;THR A 235;GLY A 236","None","0.55A","5ghzA-2wyxA:41.3","5ghzA-2wyxA:41.60"],["5GHZ_B_CEDB301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"SER A  70;TYR A 105;SER A 130;ASN A 132;ASN A 170;LYS A 234;THR A 235;GLY A 236","None","0.54A","5ghzB-2wyxA:41.3","5ghzB-2wyxA:41.60"],["5KMW_A_PNNA305_0","BETA-LACTAMASE TOHO-1","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"ASN A 104;PRO A 167;ASN A 170;ASP A 240","None","0.40A","5kmwA-2wyxA:48.0","5kmwA-2wyxA:100.00"],["5L5Z_B_BO2B201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 244;THR A 266;SER A 237;GLY A 238;ALA A 172","None","1.22A","5l5zV-2wyxA:undetectable;5l5zb-2wyxA:undetectable","5l5zV-2wyxA:21.29;5l5zb-2wyxA:23.05"],["5L5Z_N_BO2N201_1","PROTEASOME SUBUNIT BETA TYPE-2;PROTEASOME SUBUNIT BETA TYPE-1","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 244;THR A 266;SER A 237;GLY A 238;ALA A 172","None","1.22A","5l5zH-2wyxA:undetectable;5l5zN-2wyxA:undetectable","5l5zH-2wyxA:21.29;5l5zN-2wyxA:23.05"],["5LF3_B_BO2B305_1","PROTEASOME SUBUNIT BETA TYPE-6","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 244;THR A 266;SER A 237;GLY A 238;ALA A 172","None","1.22A","5lf3b-2wyxA:undetectable","5lf3b-2wyxA:21.35"],["5LF3_N_BO2N304_1","PROTEASOME SUBUNIT BETA TYPE-6","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"THR A 244;THR A 266;SER A 237;GLY A 238;ALA A 172","None","1.21A","5lf3N-2wyxA:undetectable","5lf3N-2wyxA:21.35"],["5M0I_B_ACTB303_0","SWI5-DEPENDENT HO EXPRESSION PROTEIN 2","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"VAL A  74;ASN A 214;ASP A 233;LEU A 211","None","1.33A","5m0iB-2wyxA:undetectable","5m0iB-2wyxA:24.20"],["6B5Y_A_9F2A302_1","BETA-LACTAMASE;BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"PRO A 107;TYR A 129;THR A 215;THR A 216;ASP A 240","None","0.54A","6b5yA-2wyxA:40.4;6b5yB-2wyxA:40.5","6b5yA-2wyxA:18.53;6b5yB-2wyxA:18.53"],["6B5Y_B_9F2B400_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",10,"CYH A  69;SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238;ASP A 240","None","0.49A","6b5yB-2wyxA:40.5","6b5yB-2wyxA:18.53"],["6B5Y_C_9F2C302_1","BETA-LACTAMASE;BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"PRO A 107;TYR A 129;THR A 215;THR A 216;ASP A 240","None","0.64A","6b5yC-2wyxA:40.6;6b5yD-2wyxA:40.6","6b5yC-2wyxA:18.53;6b5yD-2wyxA:18.53"],["6B5Y_D_9F2D400_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",9,"CYH A  69;SER A  70;SER A 130;ASN A 170;THR A 216;THR A 235;GLY A 236;GLY A 238;ASP A 240","None","0.44A","6b5yD-2wyxA:40.6","6b5yD-2wyxA:18.53"],["6B5Y_D_9F2D400_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",9,"CYH A  69;SER A  70;SER A 130;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238;ASP A 240","None","0.48A","6b5yD-2wyxA:40.6","6b5yD-2wyxA:18.53"],["6B68_A_9F2A302_1","BETA-LACTAMASE;BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"PRO A 107;TYR A 129;THR A 215;THR A 216;ASP A 240","None","0.52A","6b68A-2wyxA:40.8;6b68B-2wyxA:40.7","6b68A-2wyxA:18.53;6b68B-2wyxA:18.53"],["6B68_B_9F2B301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",10,"CYH A  69;SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238;ASP A 240","None","0.42A","6b68B-2wyxA:40.7","6b68B-2wyxA:18.53"],["6B68_C_9F2C302_1","BETA-LACTAMASE;BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"PRO A 107;TYR A 129;THR A 215;THR A 216;ASP A 240","None","0.61A","6b68C-2wyxA:40.7;6b68D-2wyxA:40.6","6b68C-2wyxA:18.53;6b68D-2wyxA:18.53"],["6B68_D_9F2D400_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;GLY A 236;GLY A 238;ASP A 240","None","0.52A","6b68D-2wyxA:40.6","6b68D-2wyxA:18.53"],["6B69_A_9F2A302_1","BETA-LACTAMASE;BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"PRO A 107;TYR A 129;THR A 215;THR A 216;ASP A 240","None","0.56A","6b69A-2wyxA:40.6;6b69B-2wyxA:40.5","6b69A-2wyxA:18.53;6b69B-2wyxA:18.53"],["6B69_B_9F2B301_1","BETA-LACTAMASE;BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",10,"SER A  70;SER A 130;PRO A 167;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238;ASP A 240","None","0.50A","6b69A-2wyxA:40.6;6b69B-2wyxA:40.5","6b69A-2wyxA:18.53;6b69B-2wyxA:18.53"],["6B69_C_9F2C302_1","BETA-LACTAMASE;BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"PRO A 107;TYR A 129;THR A 215;THR A 216;ASP A 240","None","0.54A","6b69C-2wyxA:40.6;6b69D-2wyxA:40.5","6b69C-2wyxA:18.53;6b69D-2wyxA:18.53"],["6B69_D_9F2D301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",9,"CYH A  69;SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238","None","0.36A","6b69D-2wyxA:40.5","6b69D-2wyxA:18.53"],["6B6A_A_9F2A302_1","BETA-LACTAMASE;BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"PRO A 107;TYR A 129;THR A 215;THR A 216;ASP A 240","None","0.60A","6b6aA-2wyxA:40.4;6b6aB-2wyxA:40.6","6b6aA-2wyxA:18.53;6b6aB-2wyxA:18.53"],["6B6A_B_9F2B301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",10,"CYH A  69;SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238;ASP A 240","None","0.45A","6b6aB-2wyxA:40.6","6b6aB-2wyxA:18.53"],["6B6A_C_9F2C302_1","BETA-LACTAMASE;BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",5,"PRO A 107;TYR A 129;THR A 215;THR A 216;ASP A 240","None","0.55A","6b6aC-2wyxA:40.5;6b6aD-2wyxA:40.6","6b6aC-2wyxA:18.53;6b6aD-2wyxA:18.53"],["6B6A_D_9F2D301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"SER A  70;SER A 130;ASN A 170;LYS A 234;THR A 235;GLY A 236;GLY A 238;ASP A 240","None","0.37A","6b6aD-2wyxA:40.6","6b6aD-2wyxA:18.53"],["6B6C_A_9F2A301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"SER A  70;SER A 130;PRO A 167;ASN A 170;LYS A 234;THR A 235;GLY A 236;GLY A 238","None","0.64A","6b6cA-2wyxA:40.5","6b6cA-2wyxA:18.53"],["6B6D_A_9F2A302_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"CYH A  69;SER A  70;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238","None","0.47A","6b6dA-2wyxA:40.3","6b6dA-2wyxA:18.53"],["6B6D_A_9F2A302_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",7,"CYH A  69;SER A  70;SER A 130;LYS A 234;THR A 235;GLY A 236;GLY A 238","None","0.56A","6b6dA-2wyxA:40.3","6b6dA-2wyxA:18.53"],["6B6E_A_9F2A302_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",8,"SER A  70;SER A 130;ASN A 170;THR A 216;LYS A 234;THR A 235;GLY A 236;GLY A 238","None","0.41A","6b6eA-2wyxA:40.5","6b6eA-2wyxA:18.53"],["6B6F_A_9F2A301_1","BETA-LACTAMASE","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",10,"CYH A  69;SER A  70;SER A 130;PRO A 167;ASN A 170;LYS A 234;THR A 235;GLY A 236;GLY A 238;ASP A 240","None","0.65A","6b6fA-2wyxA:40.2","6b6fA-2wyxA:18.53"],["6C79_A_CE3A301_1","BETA-LACTAMASE TOHO-1","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",11,"ASN A 104;TYR A 105;SER A 130;ASN A 132;ASN A 170;THR A 216;LYS A 234;GLY A 236;SER A 237;GLY A 238;ASN A 274","None","0.39A","6c79A-2wyxA:47.7","6c79A-2wyxA:98.72"],["6C79_A_CE3A301_2","BETA-LACTAMASE TOHO-1","2wyx","BETA-LACTAMSE TOHO-1","Escherichia coli",4,"CYH A  69;PRO A 167;THR A 235;ASP A 240","None","0.59A","6c79A-2wyxA:47.7","6c79A-2wyxA:98.72"]]