SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2wz9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BDM_A_TMIA503_1
(CYTOCHROME P450 2B4)		 2wz9 GLUTAREDOXIN-3
(Homo
sapiens) 		4 / 8 LEU A  26
VAL A  66
LEU A  68
VAL A  76
 None
 1.03A 2bdmA-2wz9A:
undetectable		 2bdmA-2wz9A:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_B_TPFB1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 2wz9 GLUTAREDOXIN-3
(Homo
sapiens) 		4 / 8 ALA A 103
ALA A 105
THR A 109
LEU A  56
 None
 1.04A 2wx2B-2wz9A:
undetectable		 2wx2B-2wz9A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_B_BEZB1_0
(HEME-BINDING PROTEIN
HUTZ)		 2wz9 GLUTAREDOXIN-3
(Homo
sapiens) 		4 / 6 GLN A  48
PHE A  88
PRO A  86
LEU A 100
 None
 1.03A 3tgvB-2wz9A:
undetectable		 3tgvB-2wz9A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TGV_D_BEZD1_0
(HEME-BINDING PROTEIN
HUTZ)		 2wz9 GLUTAREDOXIN-3
(Homo
sapiens) 		4 / 6 GLN A  48
PHE A  88
PRO A  86
LEU A 100
 None
 0.98A 3tgvD-2wz9A:
undetectable		 3tgvD-2wz9A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2wz9 GLUTAREDOXIN-3
(Homo
sapiens) 		4 / 8 ASP A  98
HIS A 104
HIS A 115
GLU A 107
 None
 1.20A 6mn4C-2wz9A:
undetectable		 6mn4C-2wz9A:
19.46