SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x0q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AXW_A_MTXA732_1
(THYMIDYLATE SYNTHASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A  33
LEU A 111
LEU A  28
VAL A 166
ALA A 167
 None
 1.15A 1axwA-2x0qA:
undetectable		 1axwA-2x0qA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 PHE A 174
HIS A 130
GLY A 181
TYR A 179
 None
 1.12A 1c8lA-2x0qA:
undetectable		 1c8lA-2x0qA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_B_SAMB105_0
(PROTEIN (MET
REPRESSOR))		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 LEU A 519
HIS A  79
HIS A 514
PHE A 512
GLY A 510
 None
 1.35A 1cmaA-2x0qA:
undetectable
1cmaB-2x0qA:
undetectable		 1cmaA-2x0qA:
12.03
1cmaB-2x0qA:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_1
(ESTROGEN RECEPTOR)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 LEU A 424
TRP A 423
LEU A 409
ILE A 154
LEU A 455
 None
 1.15A 1errB-2x0qA:
undetectable		 1errB-2x0qA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HMY_A_SAMA328_0
(HAEIII
METHYLTRANSFERASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 8 PHE A 289
GLU A 155
ASP A 150
PRO A 382
LEU A 383
 None
 1.37A 1hmyA-2x0qA:
undetectable		 1hmyA-2x0qA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 PHE A 289
GLN A 282
LYS A 300
VAL A 299
 None
None
ATP  A1607 (-2.6A)
None
 1.48A 1l2iB-2x0qA:
undetectable		 1l2iB-2x0qA:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 HIS A 514
PHE A 512
GLY A 510
LEU A 519
HIS A  79
 None
 1.44A 1mjqA-2x0qA:
undetectable
1mjqB-2x0qA:
undetectable		 1mjqA-2x0qA:
11.84
1mjqB-2x0qA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 10 HIS A 514
PHE A 512
GLY A 510
LEU A 519
HIS A  79
 None
 1.45A 1mjqG-2x0qA:
undetectable
1mjqH-2x0qA:
undetectable		 1mjqG-2x0qA:
11.84
1mjqH-2x0qA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 MET A 467
LEU A 455
MET A 395
THR A 502
ILE A 503
 None
 1.30A 1p93B-2x0qA:
undetectable		 1p93B-2x0qA:
17.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 GLU A 327
GLU A 380
LEU A 215
 None
 0.74A 1v8bA-2x0qA:
undetectable		 1v8bA-2x0qA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.37A 2eimJ-2x0qA:
undetectable		 2eimJ-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.43A 2eimW-2x0qA:
undetectable		 2eimW-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 HIS A 400
ALA A 143
ALA A 147
GLN A 282
GLN A 283
 None
 1.29A 2jjpA-2x0qA:
undetectable		 2jjpA-2x0qA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 HIS A 400
PRO A 184
ALA A 143
ALA A 147
GLN A 283
 None
 1.05A 2jjpA-2x0qA:
undetectable		 2jjpA-2x0qA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OMB_D_IPHD2002_0
(BENCE JONES KWR
PROTEIN -
IMMUNOGLOBULIN LIGHT
CHAIN)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 TYR A 511
HIS A 449
HIS A 162
PRO A 163
 None
ATP  A1607 (-3.6A)
ATP  A1607 (-4.4A)
None
 1.16A 2ombC-2x0qA:
undetectable
2ombD-2x0qA:
undetectable		 2ombC-2x0qA:
16.42
2ombD-2x0qA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 ARG A 348
ASN A 290
THR A 384
 None
 0.79A 2q63A-2x0qA:
undetectable		 2q63A-2x0qA:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 PHE A 512
PHE A 508
TRP A 531
GLY A 536
 None
 1.33A 2qmzA-2x0qA:
undetectable
2qmzB-2x0qA:
undetectable		 2qmzA-2x0qA:
18.05
2qmzB-2x0qA:
18.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_C_RIMC399_1
(MATRIX PROTEIN 2)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 LEU A 111
LEU A 113
ILE A 107
ARG A 108
 None
 0.97A 2rlfC-2x0qA:
undetectable
2rlfD-2x0qA:
undetectable		 2rlfC-2x0qA:
4.61
2rlfD-2x0qA:
4.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 SER A 474
PHE A 344
ILE A 470
GLY A 450
 None
None
None
ATP  A1607 ( 4.5A)
 0.79A 2v0mC-2x0qA:
undetectable		 2v0mC-2x0qA:
20.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VN0_A_TDZA501_1
(CYTOCHROME P450 2C8)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 476
LEU A 332
VAL A 481
GLU A 327
ILE A 346
 None
 1.09A 2vn0A-2x0qA:
undetectable		 2vn0A-2x0qA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W03_B_ADNB1588_1
(ACSD)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 10 HIS A 162
PRO A 163
SER A 284
ARG A 312
HIS A 449
 ATP  A1607 (-4.4A)
None
ATP  A1607 (-2.8A)
ATP  A1607 (-3.6A)
ATP  A1607 (-3.6A)
 0.73A 2w03B-2x0qA:
31.3		 2w03B-2x0qA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9H_A_TOPA1160_1
(DIHYDROFOLATE
REDUCTASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 10 LEU A 533
ALA A 535
LEU A 432
VAL A 428
PHE A 530
 None
 1.14A 2w9hA-2x0qA:
undetectable		 2w9hA-2x0qA:
12.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		8 / 8 GLY A 161
HIS A 162
ILE A 285
ASN A 307
MET A 308
ALA A 396
HIS A 449
GLU A 451
 ATP  A1607 (-3.4A)
ATP  A1607 (-4.4A)
None
ATP  A1607 (-3.7A)
ATP  A1607 (-3.3A)
ATP  A1607 (-3.5A)
ATP  A1607 (-3.6A)
ATP  A1607 ( 2.6A)
 0.60A 2x0pA-2x0qA:
57.6		 2x0pA-2x0qA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 ILE A 538
LEU A 557
PHE A 558
ARG A 532
 None
 1.21A 2zxwN-2x0qA:
undetectable
2zxwW-2x0qA:
undetectable		 2zxwN-2x0qA:
21.83
2zxwW-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.38A 3ag1J-2x0qA:
undetectable		 3ag1J-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.36A 3ag2J-2x0qA:
undetectable		 3ag2J-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.36A 3ag4J-2x0qA:
undetectable		 3ag4J-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 PHE A 174
HIS A 130
GLY A 181
TYR A 179
 None
 1.13A 3dd1A-2x0qA:
2.1		 3dd1A-2x0qA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_2
(GENOME POLYPROTEIN)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 4 PHE A 355
TYR A 242
VAL A 299
LEU A 377
 None
 1.20A 3keeD-2x0qA:
0.2		 3keeD-2x0qA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_B_PNNB5002_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 ASN A 596
ALA A 599
ALA A 559
ARG A 602
 None
 1.41A 3kp2B-2x0qA:
undetectable		 3kp2B-2x0qA:
13.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q5S_A_ACHA1289_0
(MULTIDRUG-EFFLUX
TRANSPORTER 1
REGULATOR)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 VAL A  29
ASN A  25
TYR A  68
GLU A 106
 None
 1.22A 3q5sA-2x0qA:
undetectable		 3q5sA-2x0qA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4II8_A_010A210_0
(LYSOZYME C)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 ASP A  99
GLN A 102
ASN A  25
ILE A 125
 None
 1.24A 4ii8A-2x0qA:
undetectable		 4ii8A-2x0qA:
12.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 MET A 467
LEU A 455
MET A 395
THR A 502
ILE A 503
 None
 1.19A 4p6xG-2x0qA:
undetectable		 4p6xG-2x0qA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 MET A 467
LEU A 455
MET A 395
THR A 502
ILE A 503
 None
 1.21A 4p6xI-2x0qA:
undetectable		 4p6xI-2x0qA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_B_1LDB501_0
(CYTOSINE DEAMINASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 563
HIS A 564
GLU A 509
GLU A  39
LEU A 567
 None
 1.38A 4r88B-2x0qA:
undetectable		 4r88B-2x0qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_C_1LDC501_0
(CYTOSINE DEAMINASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 563
HIS A 564
GLU A 509
GLU A  39
LEU A 567
 None
 1.38A 4r88C-2x0qA:
undetectable		 4r88C-2x0qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_D_1LDD501_0
(CYTOSINE DEAMINASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 563
HIS A 564
GLU A 509
GLU A  39
LEU A 567
 None
 1.36A 4r88D-2x0qA:
undetectable		 4r88D-2x0qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_E_1LDE501_0
(CYTOSINE DEAMINASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 563
HIS A 564
GLU A 509
GLU A  39
LEU A 567
 None
 1.37A 4r88E-2x0qA:
undetectable		 4r88E-2x0qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R88_F_1LDF502_0
(CYTOSINE DEAMINASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 563
HIS A 564
GLU A 509
GLU A  39
LEU A 567
 None
 1.36A 4r88F-2x0qA:
undetectable		 4r88F-2x0qA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYK_A_OAQA302_0
(SULFOTRANSFERASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 PRO A 448
LEU A 435
VAL A 507
LEU A 424
THR A 516
 None
 1.27A 5bykA-2x0qA:
undetectable		 5bykA-2x0qA:
19.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FHZ_B_REAB602_1
(ALDEHYDE
DEHYDROGENASE FAMILY
1 MEMBER A3)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 9 GLY A 460
LEU A 412
TRP A 423
GLN A 152
LEU A 455
 None
 1.48A 5fhzB-2x0qA:
undetectable		 5fhzB-2x0qA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 7 LEU A  60
GLN A  45
PHE A  58
PHE A  70
 None
 0.92A 5iy5C-2x0qA:
undetectable
5iy5J-2x0qA:
undetectable		 5iy5C-2x0qA:
18.79
5iy5J-2x0qA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_2
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		3 / 3 VAL A 534
ARG A  78
PRO A 595
 None
 0.84A 5koxA-2x0qA:
undetectable		 5koxA-2x0qA:
24.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 11 ILE A 107
PHE A 103
ASN A 568
GLU A  39
ALA A  32
 None
 0.96A 5lg3A-2x0qA:
undetectable		 5lg3A-2x0qA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		5 / 12 ILE A 107
PHE A 103
ASN A 568
GLU A  39
ALA A  32
 None
 0.98A 5lg3E-2x0qA:
undetectable		 5lg3E-2x0qA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.31A 5wauJ-2x0qA:
undetectable		 5wauJ-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.32A 5x19J-2x0qA:
undetectable		 5x19J-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.37A 5x1bJ-2x0qA:
undetectable		 5x1bJ-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.36A 5x1bW-2x0qA:
undetectable		 5x1bW-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.35A 5x1fW-2x0qA:
undetectable		 5x1fW-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 5 TYR A 511
MET A 395
THR A 394
LEU A 455
 None
 1.36A 5z86J-2x0qA:
undetectable		 5z86J-2x0qA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_Q_PCFQ202_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 5A,
MITOCHONDRIAL
CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x0q ALCALIGIN
BIOSYNTHESIS PROTEIN
(Bordetella
bronchiseptica) 		4 / 6 TYR A  68
ILE A  87
ALA A 100
ASP A  64
 None
 0.91A 6hu9m-2x0qA:
undetectable
6hu9q-2x0qA:
undetectable		 6hu9m-2x0qA:
22.45
6hu9q-2x0qA:
12.50