SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x11'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 2x11 EPHRIN-A5
(Homo
sapiens) 		4 / 7 ARG B 135
THR B 166
ILE B  58
ASN B  59
 None
 1.11A 2jc9A-2x11B:
undetectable		 2jc9A-2x11B:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QL8_B_BEZB143_0
(PUTATIVE REDOX
PROTEIN)		 2x11 EPHRIN-A5
(Homo
sapiens) 		4 / 6 TYR B  81
THR B  78
ARG B  80
PRO B  67
 None
 1.27A 2ql8A-2x11B:
undetectable
2ql8B-2x11B:
undetectable		 2ql8A-2x11B:
18.99
2ql8B-2x11B:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_A_ACTA501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 2x11 EPHRIN-A5
(Homo
sapiens) 		4 / 7 ARG B 138
VAL B 163
ILE B  58
TYR B 140
 None
 1.13A 2yfbA-2x11B:
undetectable		 2yfbA-2x11B:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YFB_B_ACTB501_0
(METHYL-ACCEPTING
CHEMOTAXIS
TRANSDUCER)		 2x11 EPHRIN-A5
(Homo
sapiens) 		4 / 6 ARG B 138
VAL B 163
ILE B  58
TYR B 140
 None
 1.09A 2yfbB-2x11B:
undetectable		 2yfbB-2x11B:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P6H_A_IBPA133_1
(FATTY ACID-BINDING
PROTEIN, ADIPOCYTE)		 2x11 EPHRIN-A5
(Homo
sapiens) 		4 / 7 ILE B  58
VAL B 163
ARG B 138
TYR B 140
 None
 1.09A 3p6hA-2x11B:
undetectable		 3p6hA-2x11B:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2x11 EPHRIN-A5
(Homo
sapiens) 		4 / 4 GLY B 137
PRO B 136
VAL B 163
ARG B 138
 None
 1.42A 5uunA-2x11B:
0.0
5uunB-2x11B:
0.0		 5uunA-2x11B:
18.46
5uunB-2x11B:
18.46