SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x1f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4003_1
(SERUM ALBUMIN)		 2x1f MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 6 VAL A  41
GLY A  42
ALA A  75
LEU A  79
 None
 0.75A 1e7bB-2x1fA:
undetectable		 1e7bB-2x1fA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C2B_E_SAME500_0
(THREONINE SYNTHASE
1, CHLOROPLASTIC)		 2x1f MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		5 / 11 GLY A  42
SER A  71
PHE A  66
LEU A  47
ASP A  36
 None
 1.50A 2c2bE-2x1fA:
undetectable
2c2bF-2x1fA:
undetectable		 2c2bE-2x1fA:
10.25
2c2bF-2x1fA:
10.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 2x1f MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  62
GLY A  92
CYH A  91
LYS A  90
 None
G  B   1 ( 3.6A)
None
U  B   2 ( 4.6A)
 1.37A 2yldA-2x1fA:
undetectable		 2yldA-2x1fA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 2x1f MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  62
GLY A  92
CYH A  91
LYS A  90
 None
G  B   1 ( 3.6A)
None
U  B   2 ( 4.6A)
 1.42A 2ylgA-2x1fA:
undetectable		 2ylgA-2x1fA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 2x1f MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  62
GLY A  92
CYH A  91
LYS A  90
 None
G  B   1 ( 3.6A)
None
U  B   2 ( 4.6A)
 1.33A 3zwiA-2x1fA:
undetectable		 3zwiA-2x1fA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2x1f MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		3 / 3 ASN A  80
LEU A  37
PHE A  88
 None
 0.71A 4dajB-2x1fA:
undetectable		 4dajB-2x1fA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 2x1f MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  62
GLY A  92
CYH A  91
LYS A  90
 None
G  B   1 ( 3.6A)
None
U  B   2 ( 4.6A)
 1.35A 5jliA-2x1fA:
undetectable		 5jliA-2x1fA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 2x1f MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 5 ALA A  62
GLY A  92
CYH A  91
LYS A  90
 None
G  B   1 ( 3.6A)
None
U  B   2 ( 4.6A)
 1.32A 5jt4A-2x1fA:
undetectable		 5jt4A-2x1fA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 2x1f MRNA
3'-END-PROCESSING
PROTEIN RNA15
(Saccharomyces
cerevisiae) 		4 / 8 PRO A  16
TYR A  93
ASP A  68
VAL A  76
 None
 1.04A 5nzyA-2x1fA:
undetectable		 5nzyA-2x1fA:
14.75