SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x31'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 2x31 MAGNESIUM-CHELATASE
60 KDA SUBUNIT
(Rhodobacter
capsulatus) 		5 / 12 GLY A 114
ALA A 137
ASP A 113
ALA A  21
ALA A 147
 None
 1.05A 3jb1A-2x31A:
undetectable		 3jb1A-2x31A:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 2x31 MAGNESIUM-CHELATASE
60 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 4 ASP A 113
ASP A  16
GLY A  82
THR A  55
 None
 1.09A 3tl9B-2x31A:
undetectable		 3tl9B-2x31A:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 2x31 MAGNESIUM-CHELATASE
60 KDA SUBUNIT
(Rhodobacter
capsulatus) 		5 / 12 VAL A  59
LEU A 111
ALA A 109
LEU A  11
THR A  70
 None
 1.10A 4x1kA-2x31A:
3.1
4x1kB-2x31A:
4.0		 4x1kA-2x31A:
19.21
4x1kB-2x31A:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 2x31 MAGNESIUM-CHELATASE
60 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 7 ASP A  16
PHE A  52
GLY A  54
GLY A  82
 None
 0.78A 5n9xA-2x31A:
undetectable		 5n9xA-2x31A:
18.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2x31 MAGNESIUM-CHELATASE
60 KDA SUBUNIT
(Rhodobacter
capsulatus) 		4 / 8 VAL A 136
PHE A  13
LEU A 111
MET A 182
 None
 0.79A 5nujA-2x31A:
undetectable		 5nujA-2x31A:
17.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IE8_A_CHDA201_0
(REGULATORY PROTEIN)		 2x31 MAGNESIUM-CHELATASE
60 KDA SUBUNIT
(Rhodobacter
capsulatus) 		5 / 12 ILE A  50
ALA A  40
LEU A  61
ASP A  45
LEU A  37
 None
 1.33A 6ie8A-2x31A:
undetectable		 6ie8A-2x31A:
25.33