SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x3k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DYR_A_TOPA407_1
(DIHYDROFOLATE
REDUCTASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 11 ILE A 280
ALA A 191
LEU A 139
GLU A 193
ILE A 300
 None
 1.07A 1dyrA-2x3kA:
undetectable		 1dyrA-2x3kA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4002_1
(SERUM ALBUMIN)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 6 LEU A  74
VAL A  93
VAL A  78
GLN A  87
 None
 1.06A 1e7aB-2x3kA:
undetectable		 1e7aB-2x3kA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXH_B_PACB1001_0
(PENICILLIN ACYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 7 MET A  45
SER A  91
PHE A  75
ALA A  52
 None
 1.05A 1fxhA-2x3kA:
undetectable
1fxhB-2x3kA:
undetectable		 1fxhA-2x3kA:
15.65
1fxhB-2x3kA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FXV_B_PNNB1001_0
(PENICILLIN ACYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 7 MET A  45
SER A  91
PHE A  75
ALA A  52
 None
 1.00A 1fxvA-2x3kA:
undetectable
1fxvB-2x3kA:
2.0		 1fxvA-2x3kA:
15.65
1fxvB-2x3kA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PNL_B_PACB559_0
(PENICILLIN
AMIDOHYDROLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 8 MET A  45
SER A  91
PHE A  75
ALA A  52
 None
 1.01A 1pnlA-2x3kA:
undetectable
1pnlB-2x3kA:
2.6		 1pnlA-2x3kA:
15.65
1pnlB-2x3kA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_B_FUAB703_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 VAL A 273
ALA A 199
HIS A 201
 None
 0.77A 1q23C-2x3kA:
undetectable		 1q23C-2x3kA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 4 ALA A 198
VAL A 273
ALA A 199
HIS A 201
 None
 1.04A 1q23A-2x3kA:
undetectable		 1q23A-2x3kA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 4 ALA A 198
VAL A 273
ALA A 199
HIS A 201
 None
 1.06A 1q23F-2x3kA:
undetectable		 1q23F-2x3kA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 VAL A 273
ALA A 199
HIS A 201
 None
 0.77A 1q23G-2x3kA:
undetectable		 1q23G-2x3kA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_K_FUAK712_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 VAL A 273
ALA A 199
HIS A 201
 None
 0.73A 1q23L-2x3kA:
undetectable		 1q23L-2x3kA:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 7 ASP A 464
ASN A 447
SER A 279
ARG A 281
 SO4  A1589 ( 3.4A)
AMP  A1588 ( 4.1A)
SO4  A1589 (-3.0A)
None
 1.45A 1rqpB-2x3kA:
undetectable		 1rqpB-2x3kA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9P_B_DESB459_1
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 LEU A 110
LEU A 115
ALA A 116
GLU A 119
TYR A 130
 None
 1.28A 1s9pB-2x3kA:
undetectable		 1s9pB-2x3kA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 ASP A 252
PHE A 360
ARG A 254
 None
 0.81A 2a3aA-2x3kA:
undetectable		 2a3aA-2x3kA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F0Z_A_ZMRA381_1
(SIALIDASE 2)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLU A 442
ARG A 501
ASN A 447
GLU A 341
ARG A 281
 AMP  A1588 ( 4.3A)
None
AMP  A1588 ( 4.1A)
None
None
 1.41A 2f0zA-2x3kA:
undetectable		 2f0zA-2x3kA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_2
(FATTY ACID-BINDING
PROTEIN, LIVER)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 7 LEU A  26
LEU A  23
PRO A 105
ARG A 113
 None
 0.91A 2jn3A-2x3kA:
undetectable		 2jn3A-2x3kA:
12.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W03_A_ADNA1588_1
(ACSD)		 2x3k ACSD
(Dickeya
chrysanthemi) 		10 / 10 LEU A 166
HIS A 170
PRO A 171
ILE A 300
THR A 301
ARG A 305
HIS A 444
LEU A 445
GLN A 446
ASN A 509
 None
AMP  A1588 (-3.8A)
None
None
AMP  A1588 (-3.2A)
AMP  A1588 (-3.7A)
AMP  A1588 (-3.3A)
AMP  A1588 (-4.0A)
SO4  A1589 ( 2.8A)
AMP  A1588 (-3.1A)
 0.52A 2w03A-2x3kA:
60.2		 2w03A-2x3kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W03_A_ADNA1588_1
(ACSD)		 2x3k ACSD
(Dickeya
chrysanthemi) 		7 / 10 LEU A 166
PRO A 171
ILE A 280
HIS A 444
LEU A 445
GLN A 446
ASN A 509
 None
None
None
AMP  A1588 (-3.3A)
AMP  A1588 (-4.0A)
SO4  A1589 ( 2.8A)
AMP  A1588 (-3.1A)
 1.17A 2w03A-2x3kA:
60.2		 2w03A-2x3kA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W03_B_ADNB1588_1
(ACSD)		 2x3k ACSD
(Dickeya
chrysanthemi) 		10 / 10 LEU A 166
HIS A 170
PRO A 171
SER A 279
THR A 301
ARG A 305
HIS A 444
LEU A 445
GLN A 446
ASN A 509
 None
AMP  A1588 (-3.8A)
None
SO4  A1589 (-3.0A)
AMP  A1588 (-3.2A)
AMP  A1588 (-3.7A)
AMP  A1588 (-3.3A)
AMP  A1588 (-4.0A)
SO4  A1589 ( 2.8A)
AMP  A1588 (-3.1A)
 0.57A 2w03B-2x3kA:
62.2		 2w03B-2x3kA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 8 GLY A 169
HIS A 170
ILE A 280
HIS A 444
 AMP  A1588 ( 4.5A)
AMP  A1588 (-3.8A)
None
AMP  A1588 (-3.3A)
 0.90A 2x0pA-2x3kA:
30.3		 2x0pA-2x3kA:
23.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZLC_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 5 LEU A  74
ILE A  62
TRP A  41
TYR A  89
 None
 1.06A 2zlcA-2x3kA:
undetectable		 2zlcA-2x3kA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A9E_B_REAB1_1
(RETINOIC ACID
RECEPTOR ALPHA)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 11 PHE A 388
LEU A 511
SER A  86
VAL A 460
LEU A 450
 None
 1.40A 3a9eB-2x3kA:
undetectable		 3a9eB-2x3kA:
15.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 9 PRO A 219
VAL A 222
GLY A 225
ILE A 292
GLY A 343
 None
 1.06A 3csjB-2x3kA:
undetectable		 3csjB-2x3kA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_A_SAMA300_0
(PUTATIVE RRNA
METHYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLY A 225
ASP A 289
ILE A 212
GLY A 213
THR A 218
 None
 0.98A 3eeyA-2x3kA:
undetectable		 3eeyA-2x3kA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_B_SAMB300_0
(PUTATIVE RRNA
METHYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLY A 225
ASP A 289
ILE A 212
GLY A 213
THR A 218
 None
 0.99A 3eeyB-2x3kA:
undetectable		 3eeyB-2x3kA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_0
(PUTATIVE RRNA
METHYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLY A 225
ASP A 289
ILE A 212
GLY A 213
THR A 218
 None
 0.99A 3eeyC-2x3kA:
undetectable		 3eeyC-2x3kA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_0
(PUTATIVE RRNA
METHYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLY A 225
ASP A 289
ILE A 212
GLY A 213
THR A 218
 None
 0.99A 3eeyD-2x3kA:
undetectable		 3eeyD-2x3kA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_0
(PUTATIVE RRNA
METHYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLY A 225
ASP A 289
ILE A 212
GLY A 213
THR A 218
 None
 0.99A 3eeyE-2x3kA:
undetectable		 3eeyE-2x3kA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_F_SAMF300_0
(PUTATIVE RRNA
METHYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLY A 225
ASP A 289
ILE A 212
GLY A 213
THR A 218
 None
 0.98A 3eeyF-2x3kA:
undetectable		 3eeyF-2x3kA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_H_SAMH300_0
(PUTATIVE RRNA
METHYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLY A 225
ASP A 289
ILE A 212
GLY A 213
THR A 218
 None
 0.99A 3eeyH-2x3kA:
undetectable		 3eeyH-2x3kA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_I_SAMI300_0
(PUTATIVE RRNA
METHYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLY A 225
ASP A 289
ILE A 212
GLY A 213
THR A 218
 None
 0.99A 3eeyI-2x3kA:
undetectable		 3eeyI-2x3kA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_J_SAMJ300_0
(PUTATIVE RRNA
METHYLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLY A 225
ASP A 289
ILE A 212
GLY A 213
THR A 218
 None
 1.00A 3eeyJ-2x3kA:
undetectable		 3eeyJ-2x3kA:
14.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCP_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 10 LEU A 551
ILE A 540
PRO A 586
SER A 585
TRP A 530
 None
 1.49A 3hcpB-2x3kA:
0.0		 3hcpB-2x3kA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 11 LEU A 427
LEU A 551
GLY A 438
HIS A 437
LEU A 433
 None
 1.37A 3hm1B-2x3kA:
undetectable		 3hm1B-2x3kA:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 GLU A 362
GLY A 365
THR A 364
 None
 0.57A 3iazA-2x3kA:
undetectable		 3iazA-2x3kA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 7 ASP A 101
GLN A 103
TYR A  94
GLU A  44
 None
 1.16A 3l2vA-2x3kA:
undetectable		 3l2vA-2x3kA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_D_ROCD100_3
(PROTEASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 ARG A 124
VAL A 581
THR A 564
 None
 0.85A 3nduD-2x3kA:
undetectable		 3nduD-2x3kA:
9.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_1
(YAEB-LIKE PROTEIN
RPA0152)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 LEU A 426
LEU A 445
GLY A 385
THR A 386
LEU A 511
 None
AMP  A1588 (-4.0A)
None
None
None
 1.29A 3okxB-2x3kA:
undetectable		 3okxB-2x3kA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 ASN A 297
LEU A 185
PHE A 249
 None
 0.80A 4dajB-2x3kA:
undetectable		 4dajB-2x3kA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FOG_C_C2FC302_0
(THYMIDYLATE SYNTHASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 11 ILE A 502
LEU A 336
GLY A 438
PHE A 434
VAL A 468
 None
 1.24A 4fogC-2x3kA:
undetectable		 4fogC-2x3kA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G8Z_X_TOPX301_1
(DIHYDROFOLATE
REDUCTASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 10 ILE A 280
ALA A 191
LEU A 139
GLU A 193
ILE A 300
 None
 1.12A 4g8zX-2x3kA:
undetectable		 4g8zX-2x3kA:
14.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWX_A_ZMRA513_2
(NEURAMINIDASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 ARG A 179
TRP A 181
ILE A 280
 None
 0.83A 4mwxA-2x3kA:
undetectable		 4mwxA-2x3kA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 10 ASP A 480
LEU A 321
LEU A 470
ILE A 476
LEU A 491
 None
 0.87A 4odoA-2x3kA:
undetectable		 4odoA-2x3kA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 10 ASP A 480
LEU A 321
LEU A 470
ILE A 476
LEU A 491
 None
 0.85A 4odoB-2x3kA:
undetectable		 4odoB-2x3kA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 10 ASP A 480
LEU A 321
LEU A 470
ILE A 476
LEU A 491
 None
 0.83A 4odoC-2x3kA:
undetectable		 4odoC-2x3kA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_A_FK5A201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 ASP A 480
LEU A 321
LEU A 470
ILE A 476
LEU A 491
 None
 0.97A 4odrA-2x3kA:
undetectable
4odrB-2x3kA:
undetectable		 4odrA-2x3kA:
10.48
4odrB-2x3kA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODR_B_FK5B201_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD,
PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP1A CHIMERA)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 11 ASP A 480
LEU A 321
LEU A 470
ILE A 476
LEU A 491
 None
 0.89A 4odrA-2x3kA:
undetectable
4odrB-2x3kA:
undetectable		 4odrA-2x3kA:
10.48
4odrB-2x3kA:
10.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 11 LEU A 566
GLU A 131
LEU A 129
ALA A 112
LEU A 115
 None
 1.04A 4wg0H-2x3kA:
undetectable
4wg0I-2x3kA:
undetectable
4wg0J-2x3kA:
undetectable		 4wg0H-2x3kA:
2.54
4wg0I-2x3kA:
2.54
4wg0J-2x3kA:
2.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 ASN A  24
LEU A  37
PHE A  84
 None
 0.75A 5dsgA-2x3kA:
undetectable		 5dsgA-2x3kA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QSA615_1
(SERUM ALBUMIN)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 8 LEU A 516
TYR A  89
ARG A  80
ILE A  27
 None
 0.94A 5v0vA-2x3kA:
undetectable		 5v0vA-2x3kA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_A_RITA602_2
(CYTOCHROME P450 3A5)		 2x3k ACSD
(Dickeya
chrysanthemi) 		3 / 3 ARG A 538
PHE A 434
LEU A 427
 None
 0.82A 5veuA-2x3kA:
2.0		 5veuA-2x3kA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 8 GLY A 213
ARG A 323
GLN A 324
VAL A 316
 None
 0.98A 5vlmA-2x3kA:
1.7		 5vlmA-2x3kA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 8 GLY A 213
ARG A 323
VAL A 316
ASP A 319
 None
 0.99A 5vlmA-2x3kA:
1.7		 5vlmA-2x3kA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 6 ALA A 517
GLN A 399
GLN A 395
ASP A 393
 None
 1.06A 5y9aA-2x3kA:
undetectable		 5y9aA-2x3kA:
14.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A7P_A_9SCA601_0
(SERUM ALBUMIN)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 LEU A 491
ILE A 476
LEU A 461
GLY A 438
LEU A 321
 None
 1.18A 6a7pA-2x3kA:
undetectable		 6a7pA-2x3kA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEC_C_RBTC601_1
(SCAFFOLD PROTEIN D13)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 12 GLU A 163
PRO A 192
VAL A 140
PRO A 171
PHE A 168
 None
 1.27A 6becA-2x3kA:
undetectable
6becB-2x3kA:
undetectable
6becC-2x3kA:
undetectable		 6becA-2x3kA:
19.48
6becB-2x3kA:
19.48
6becC-2x3kA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8P_B_ACTB804_0
(UNCHARACTERIZED
PROTEIN)		 2x3k ACSD
(Dickeya
chrysanthemi) 		4 / 4 HIS A 510
VAL A 460
LEU A 426
ALA A 384
 None
 1.27A 6d8pB-2x3kA:
undetectable		 6d8pB-2x3kA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_D95A816_0
(GEPHYRIN)		 2x3k ACSD
(Dickeya
chrysanthemi) 		5 / 11 MET A 383
LEU A 160
LEU A 166
PRO A 192
ILE A 280
 None
 1.24A 6fgcA-2x3kA:
undetectable		 6fgcA-2x3kA:
7.58