SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x3m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK5_A_T44A1008_1
(SERUM ALBUMIN)		 2x3m HYPOTHETICAL PROTEIN
ORF239
(Pyrobaculum
spherical
virus) 		5 / 10 ALA A 184
GLU A 200
LYS A 176
VAL A 177
VAL A 194
 None
 1.23A 1hk5A-2x3mA:
3.7		 1hk5A-2x3mA:
18.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 2x3m HYPOTHETICAL PROTEIN
ORF239
(Pyrobaculum
spherical
virus) 		5 / 12 GLY A 121
ILE A 181
GLY A 218
SER A 220
ILE A 217
 None
 1.13A 1q8jB-2x3mA:
undetectable		 1q8jB-2x3mA:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ1_A_HLTA2001_1
(FERRITIN LIGHT CHAIN)		 2x3m HYPOTHETICAL PROTEIN
ORF239
(Pyrobaculum
spherical
virus) 		4 / 4 LEU A 210
SER A 209
TYR A 211
LEU A 233
 None
 1.09A 1xz1A-2x3mA:
undetectable		 1xz1A-2x3mA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZ3_A_ICFA201_1
(FERRITIN LIGHT CHAIN)		 2x3m HYPOTHETICAL PROTEIN
ORF239
(Pyrobaculum
spherical
virus) 		4 / 4 LEU A 210
SER A 209
TYR A 211
LEU A 233
 None
 1.09A 1xz3A-2x3mA:
undetectable		 1xz3A-2x3mA:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JC9_A_ADNA1497_1
(CYTOSOLIC PURINE
5'-NUCLEOTIDASE)		 2x3m HYPOTHETICAL PROTEIN
ORF239
(Pyrobaculum
spherical
virus) 		4 / 7 ARG A 156
ASP A 157
ILE A 167
ASN A 213
 None
 1.21A 2jc9A-2x3mA:
undetectable		 2jc9A-2x3mA:
17.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 2x3m HYPOTHETICAL PROTEIN
ORF239
(Pyrobaculum
spherical
virus) 		4 / 8 ILE A 217
GLY A 218
ARG A 219
LEU A 227
 None
 0.90A 2vctB-2x3mA:
undetectable		 2vctB-2x3mA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2x3m HYPOTHETICAL PROTEIN
ORF239
(Pyrobaculum
spherical
virus) 		4 / 6 GLY A 121
GLY A 118
MET A 133
ILE A  77
 None
 0.98A 4fglD-2x3mA:
undetectable		 4fglD-2x3mA:
22.59