SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JB0_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 MET A 281
PHE A 283
ALA A 228
LEU A 260
GLY A 284
 None
 1.24A 1jb0A-2x5fA:
undetectable		 1jb0A-2x5fA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 GLY A 146
TYR A 148
ILE A 192
THR A 203
PRO A 204
 None
 0.96A 1p91B-2x5fA:
2.9		 1p91B-2x5fA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_F_SNLF6001_2
(MINERALOCORTICOID
RECEPTOR)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 5 LEU A 106
LEU A 100
LEU A  94
MET A 111
 None
 0.97A 2oaxF-2x5fA:
undetectable		 2oaxF-2x5fA:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 7 ASP A 232
TYR A 195
PRO A 196
THR A 203
 None
 1.47A 2q6kA-2x5fA:
undetectable		 2q6kA-2x5fA:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 PHE A 271
ILE A 331
TRP A  95
GLY A 236
 None
 0.93A 2qwxA-2x5fA:
undetectable
2qwxB-2x5fA:
2.7		 2qwxA-2x5fA:
19.23
2qwxB-2x5fA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 PHE A 271
ILE A 331
TRP A  95
GLY A 236
 None
 0.89A 2qx4A-2x5fA:
2.8
2qx4B-2x5fA:
2.7		 2qx4A-2x5fA:
19.86
2qx4B-2x5fA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 SER A 256
LEU A  12
LEU A 294
LEU A 260
LEU A  23
 None
 1.09A 2xn5A-2x5fA:
undetectable		 2xn5A-2x5fA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 7 ILE A 420
PHE A 363
PHE A 405
GLY A 392
 None
 0.99A 3em0B-2x5fA:
undetectable		 3em0B-2x5fA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 LEU A  91
GLU A  89
ARG A 113
GLY A 309
LEU A 311
 None
 1.30A 3hm1B-2x5fA:
undetectable		 3hm1B-2x5fA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 GLY A 266
THR A 268
ILE A 192
LEU A 124
PHE A 152
 None
PLP  A1429 (-2.8A)
None
None
None
 0.97A 3ihtA-2x5fA:
3.4		 3ihtA-2x5fA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_1
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ASN A 156
ASP A 129
ARG A 277
 None
None
PLP  A1429 (-2.9A)
 0.86A 3k13A-2x5fA:
undetectable		 3k13A-2x5fA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PCQ_A_PQNA847_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 MET A 281
PHE A 283
ALA A 228
LEU A 260
GLY A 284
 None
 1.24A 3pcqA-2x5fA:
undetectable		 3pcqA-2x5fA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FE1_A_PQNA846_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 MET A 281
PHE A 283
ALA A 228
LEU A 260
GLY A 284
 None
 1.25A 4fe1A-2x5fA:
undetectable
4fe1J-2x5fA:
undetectable		 4fe1A-2x5fA:
20.44
4fe1J-2x5fA:
7.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JJK_A_FOLA601_0
(FORMATE--TETRAHYDROF
OLATE LIGASE)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 ASN A 334
LEU A 237
TYR A 239
LEU A 338
 None
 0.82A 4jjkA-2x5fA:
undetectable		 4jjkA-2x5fA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L6V_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
FUSION PROTEIN OF
PHOTOSYSTEM I
SUBUNIT III AND
SUBUNIT IX)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 9 MET A 281
PHE A 283
ALA A 228
LEU A 260
GLY A 284
 None
 1.25A 4l6va-2x5fA:
undetectable
4l6vf-2x5fA:
undetectable		 4l6va-2x5fA:
20.31
4l6vf-2x5fA:
15.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 6 ASN A 156
MET A  30
ILE A 190
VAL A 229
 None
 0.96A 4olmA-2x5fA:
undetectable		 4olmA-2x5fA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 GLU A 105
THR A 210
HIS A 206
 None
 0.84A 4q15A-2x5fA:
undetectable		 4q15A-2x5fA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 GLU A 105
THR A 210
HIS A 206
 None
 0.84A 4q15B-2x5fA:
undetectable		 4q15B-2x5fA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOG_A_ML1A302_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 PHE A 271
ILE A 331
TRP A  95
GLY A 236
 None
 0.89A 4qogA-2x5fA:
undetectable
4qogB-2x5fA:
2.8		 4qogA-2x5fA:
19.23
4qogB-2x5fA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_D_ACTD201_0
(RETINOL-BINDING
PROTEIN 2)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ASP A 425
HIS A 357
LYS A 422
 None
 0.86A 4qzuD-2x5fA:
undetectable		 4qzuD-2x5fA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ASN A 197
PHE A 363
TYR A 239
 None
 0.89A 4u15A-2x5fA:
undetectable		 4u15A-2x5fA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_A_DIFA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 9 ALA A 220
LEU A 254
LEU A 251
ILE A 212
 None
 0.95A 4xtaA-2x5fA:
undetectable		 4xtaA-2x5fA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_1
(PROLINE--TRNA LIGASE)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 GLU A 105
THR A 210
HIS A 206
 None
 0.79A 4ydqB-2x5fA:
undetectable		 4ydqB-2x5fA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DXB_A_ESTA1000_1
(ESTROGEN RECEPTOR)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 LEU A  91
GLU A  89
ARG A 113
GLY A 309
LEU A 311
 None
 1.26A 5dxbA-2x5fA:
undetectable		 5dxbA-2x5fA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECN_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 8 ILE A 371
ALA A 395
VAL A 393
VAL A 373
 None
 0.87A 5ecnD-2x5fA:
2.2		 5ecnD-2x5fA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ALA A 250
ASN A 253
LEU A 254
 None
 0.24A 5i1nC-2x5fA:
undetectable		 5i1nC-2x5fA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1N_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ALA A 250
ASN A 253
LEU A 254
 None
 0.37A 5i1nB-2x5fA:
undetectable		 5i1nB-2x5fA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ALA A 250
ASN A 253
LEU A 254
 None
 0.13A 5i1oC-2x5fA:
undetectable		 5i1oC-2x5fA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_H_DVAH9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ALA A 250
ASN A 253
LEU A 254
 None
 0.39A 5i1oA-2x5fA:
undetectable		 5i1oA-2x5fA:
6.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ALA A 250
ASN A 253
LEU A 254
 None
 0.20A 5i1pA-2x5fA:
undetectable		 5i1pA-2x5fA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ALA A 158
ASN A 159
LEU A 160
 None
 0.50A 5i1pD-2x5fA:
undetectable		 5i1pD-2x5fA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_G_DVAG9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 ALA A 250
ASN A 253
LEU A 254
 None
 0.17A 5i1pD-2x5fA:
undetectable		 5i1pD-2x5fA:
6.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		4 / 6 ILE A 401
GLY A 201
ASN A 197
ILE A 403
 None
 1.00A 5j4nB-2x5fA:
undetectable		 5j4nB-2x5fA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 11 LEU A 140
ALA A 158
ASP A 136
GLY A 128
ILE A 138
 None
 1.04A 5kr2B-2x5fA:
undetectable		 5kr2B-2x5fA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 12 LEU A   8
LEU A  12
ASN A   9
LEU A 260
LEU A 130
 None
 1.21A 5mwyA-2x5fA:
undetectable		 5mwyA-2x5fA:
19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 TYR A 367
ALA A 233
TYR A 234
 None
PLP  A1429 ( 3.8A)
PLP  A1429 (-4.4A)
 0.84A 5uunB-2x5fA:
undetectable		 5uunB-2x5fA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		3 / 3 HIS A 357
ARG A 428
ILE A 424
 None
 0.86A 6fgdA-2x5fA:
undetectable		 6fgdA-2x5fA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_E_DZPE502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 2x5f ASPARTATE_TYROSINE_P
HENYLALANINE
PYRIDOXAL-5'
PHOSPHATE-DEPENDENT
AMINOTRANSFERASE
(Staphylococcus
aureus) 		5 / 10 LEU A 251
LEU A 106
MET A 281
THR A 282
LEU A 264
 None
 1.27A 6hupD-2x5fA:
0.0
6hupE-2x5fA:
0.0		 6hupD-2x5fA:
11.66
6hupE-2x5fA:
11.16