SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x5y'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FGL_A_CLQA303_0 (RIBOSYLDIHYDRONICOTI NAMIDE DEHYDROGENASE [QUINONE])	2x5y	ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1 (Homo sapiens)	5 / 12	GLY A 848 MET A 778 VAL A 876 PHE A 880 ILE A 879	None	1.17A	4fglA-2x5yA: undetectable 4fglB-2x5yA: undetectable	4fglA-2x5yA: 20.09 4fglB-2x5yA: 20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ECO_D_LEUD602_0 (JASMONIC ACID-AMIDO SYNTHETASE JAR1)	2x5y	ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1 (Homo sapiens)	5 / 7	ALA A 788 THR A 789 VAL A 838 TYR A 833 GLU A 808	None	1.50A	5ecoD-2x5yA: undetectable	5ecoD-2x5yA: 13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5PBE_A_TYLA2001_1 (BROMODOMAIN ADJACENT TO ZINC FINGER DOMAIN PROTEIN 2B)	2x5y	ZINC FINGER CCCH-TYPE ANTIVIRAL PROTEIN 1 (Homo sapiens)	4 / 6	PRO A 887 VAL A 890 VAL A 839 ILE A 797	None	0.92A	5pbeA-2x5yA: undetectable	5pbeA-2x5yA: 18.82