SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x7m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 5 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.18A 1os2A-2x7mA:
10.2		 1os2A-2x7mA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.18A 1os2D-2x7mA:
10.1		 1os2D-2x7mA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.26A 1uttA-2x7mA:
10.5		 1uttA-2x7mA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.20A 1utzA-2x7mA:
10.5		 1utzA-2x7mA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.20A 1utzB-2x7mA:
10.5		 1utzB-2x7mA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 6 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.17A 1y93A-2x7mA:
10.8		 1y93A-2x7mA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.74A 2einA-2x7mA:
undetectable		 2einA-2x7mA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.71A 2einN-2x7mA:
undetectable		 2einN-2x7mA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.19A 2hu6A-2x7mA:
10.5		 2hu6A-2x7mA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 8 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.28A 2jihB-2x7mA:
13.9		 2jihB-2x7mA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 6 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.14A 2ow9A-2x7mA:
10.1		 2ow9A-2x7mA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.17A 2ow9B-2x7mA:
9.3		 2ow9B-2x7mA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.18A 2ozrC-2x7mA:
9.7		 2ozrC-2x7mA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.24A 2ozrD-2x7mA:
9.8		 2ozrD-2x7mA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.36A 2ozrE-2x7mA:
9.8		 2ozrE-2x7mA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 125
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.35A 2ozrF-2x7mA:
9.6		 2ozrF-2x7mA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2TSR_B_D16B409_1
(THYMIDYLATE SYNTHASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 8 ARG A  21
ILE A  18
LEU A  74
GLY A  75
 None
 0.80A 2tsrB-2x7mA:
undetectable		 2tsrB-2x7mA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.72A 3bvdA-2x7mA:
undetectable		 3bvdA-2x7mA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		5 / 12 PHE A 159
MET A 143
HIS A 125
GLY A 132
LEU A 171
 None
None
ZN  A1174 (-3.2A)
None
None
 1.20A 3i5uA-2x7mA:
undetectable		 3i5uA-2x7mA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 5 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.21A 3kecA-2x7mA:
7.3		 3kecA-2x7mA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 125
GLU A 126
HIS A 129
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
 0.16A 3kecB-2x7mA:
7.2		 3kecB-2x7mA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 5 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.18A 3likA-2x7mA:
10.6		 3likA-2x7mA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.18A 3lilA-2x7mA:
10.5		 3lilA-2x7mA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 5 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.21A 3ljgA-2x7mA:
10.6		 3ljgA-2x7mA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 5 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.20A 3lkaA-2x7mA:
10.5		 3lkaA-2x7mA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.76A 3s33A-2x7mA:
undetectable		 3s33A-2x7mA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.72A 3s38A-2x7mA:
undetectable		 3s38A-2x7mA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.77A 3s39A-2x7mA:
undetectable		 3s39A-2x7mA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.77A 3s3aA-2x7mA:
undetectable		 3s3aA-2x7mA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.79A 3s3bA-2x7mA:
undetectable		 3s3bA-2x7mA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.78A 3s3cA-2x7mA:
undetectable		 3s3cA-2x7mA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.75A 3s3dA-2x7mA:
undetectable		 3s3dA-2x7mA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 6 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.24A 4a7bA-2x7mA:
7.7		 4a7bA-2x7mA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6V_E_RBFE201_1
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT B
NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT E)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 5 VAL A 120
GLU A 122
VAL A 142
LYS A 155
 None
 1.29A 4p6vB-2x7mA:
1.5
4p6vE-2x7mA:
undetectable		 4p6vB-2x7mA:
19.00
4p6vE-2x7mA:
24.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		5 / 12 GLY A  91
LEU A  76
VAL A 152
VAL A 104
ALA A 105
 None
 0.92A 5kpcA-2x7mA:
undetectable		 5kpcA-2x7mA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 4 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.19A 5n5jA-2x7mA:
10.6		 5n5jA-2x7mA:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		4 / 5 HIS A 125
GLU A 126
HIS A 129
HIS A 135
 ZN  A1174 (-3.2A)
ZN  A1174 ( 4.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.14A 5n5kA-2x7mA:
10.6		 5n5kA-2x7mA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.68A 5x1fN-2x7mA:
undetectable		 5x1fN-2x7mA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.75A 6hu9a-2x7mA:
undetectable		 6hu9a-2x7mA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.75A 6hu9m-2x7mA:
undetectable		 6hu9m-2x7mA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 2x7m ARCHAEMETZINCIN
(Methanopyrus
kandleri) 		3 / 3 HIS A 135
HIS A 129
HIS A 125
 ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
ZN  A1174 (-3.2A)
 0.76A 6nmpN-2x7mA:
undetectable		 6nmpN-2x7mA:
15.89