SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x7v'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.45A 1c9sF-2x7vA:
undetectable
1c9sG-2x7vA:
undetectable		 1c9sF-2x7vA:
13.50
1c9sG-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.40A 1c9sH-2x7vA:
undetectable
1c9sI-2x7vA:
undetectable		 1c9sH-2x7vA:
13.50
1c9sI-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.40A 1c9sO-2x7vA:
undetectable
1c9sP-2x7vA:
undetectable		 1c9sO-2x7vA:
13.50
1c9sP-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.48A 1gtfB-2x7vA:
undetectable
1gtfC-2x7vA:
undetectable		 1gtfB-2x7vA:
13.50
1gtfC-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.43A 1gtfE-2x7vA:
undetectable
1gtfF-2x7vA:
undetectable		 1gtfE-2x7vA:
13.50
1gtfF-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 1gtfP-2x7vA:
undetectable
1gtfQ-2x7vA:
undetectable		 1gtfP-2x7vA:
13.50
1gtfQ-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 1gtfT-2x7vA:
undetectable
1gtfU-2x7vA:
undetectable		 1gtfT-2x7vA:
13.50
1gtfU-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 11 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 1gtfU-2x7vA:
undetectable
1gtfV-2x7vA:
undetectable		 1gtfU-2x7vA:
13.50
1gtfV-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.39A 1gtfL-2x7vA:
undetectable
1gtfV-2x7vA:
undetectable		 1gtfL-2x7vA:
13.50
1gtfV-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.34A 1gtnN-2x7vA:
undetectable
1gtnO-2x7vA:
undetectable		 1gtnN-2x7vA:
13.50
1gtnO-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OE2_A_CUA502_0
(DISSIMILATORY
COPPER-CONTAINING
NITRITE REDUCTASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		3 / 3 GLU A 144
HIS A 181
HIS A 109
 ZN  A1287 ( 2.4A)
ZN  A1289 ( 3.3A)
ZN  A1287 (-3.3A)
 0.48A 1oe2A-2x7vA:
undetectable		 1oe2A-2x7vA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.48A 1utdA-2x7vA:
undetectable
1utdK-2x7vA:
undetectable		 1utdA-2x7vA:
13.50
1utdK-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 1utdQ-2x7vA:
undetectable
1utdR-2x7vA:
undetectable		 1utdQ-2x7vA:
13.50
1utdR-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 1utdR-2x7vA:
undetectable
1utdS-2x7vA:
undetectable		 1utdR-2x7vA:
13.50
1utdS-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 12 THR A 179
VAL A 195
TYR A 177
ILE A 214
LEU A 198
 None
 1.20A 1z9hA-2x7vA:
undetectable		 1z9hA-2x7vA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 12 THR A 179
VAL A 195
TYR A 177
ILE A 214
LEU A 198
 None
 1.20A 1z9hB-2x7vA:
undetectable		 1z9hB-2x7vA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 12 THR A 179
VAL A 195
TYR A 177
ILE A 214
LEU A 198
 None
 1.20A 1z9hC-2x7vA:
undetectable		 1z9hC-2x7vA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 12 THR A 179
VAL A 195
TYR A 177
ILE A 214
LEU A 198
 None
 1.19A 1z9hD-2x7vA:
undetectable		 1z9hD-2x7vA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 12 PHE A  29
GLY A  26
GLY A  25
ALA A 269
PRO A  18
 None
 0.93A 2dpmA-2x7vA:
undetectable		 2dpmA-2x7vA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_D_RIMD499_1
(MATRIX PROTEIN 2)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 6 ILE A 163
ARG A 164
LEU A 160
LEU A 129
 None
 1.05A 2rlfA-2x7vA:
undetectable
2rlfD-2x7vA:
undetectable		 2rlfA-2x7vA:
11.43
2rlfD-2x7vA:
11.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0P_A_ADNA1607_1
(ALCALIGIN
BIOSYNTHESIS PROTEIN)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 8 GLY A 154
ILE A 108
HIS A 181
GLU A 144
 None
None
ZN  A1289 ( 3.3A)
ZN  A1287 ( 2.4A)
 0.94A 2x0pA-2x7vA:
undetectable		 2x0pA-2x7vA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XAT_A_CLMA301_0
(XENOBIOTIC
ACETYLTRANSFERASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		3 / 3 GLY A 182
TYR A 187
SER A 185
 None
 0.60A 2xatA-2x7vA:
undetectable		 2xatA-2x7vA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_E_VD3E2001_1
(VITAMIN D
HYDROXYLASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 12 LEU A 143
ASN A 145
LEU A 106
ILE A 141
LEU A  76
 None
 1.25A 3a50E-2x7vA:
undetectable		 3a50E-2x7vA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A7E_A_SAMA216_1
(CATECHOL
O-METHYLTRANSFERASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 6 GLY A 154
SER A 185
ILE A 153
ILE A 163
 None
 0.67A 3a7eA-2x7vA:
undetectable		 3a7eA-2x7vA:
28.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HEG_A_BAXA1_2
(MITOGEN-ACTIVATED
PROTEIN KINASE 14)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 6 VAL A 173
ILE A 125
ILE A 141
LEU A 142
 None
 0.69A 3hegA-2x7vA:
undetectable		 3hegA-2x7vA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW3_A_TOPA208_1
(DIHYDROFOLATE
REDUCTASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 LEU A 133
VAL A 167
ILE A 108
LEU A  76
ILE A 163
 None
 1.19A 3jw3A-2x7vA:
undetectable		 3jw3A-2x7vA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TZF_B_08DB280_1
(7,8-DIHYDROPTEROATE
SYNTHASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 8 PHE A 183
THR A 179
GLY A 242
PHE A 243
 None
 1.05A 3tzfB-2x7vA:
9.5		 3tzfB-2x7vA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 6 HIS A 230
HIS A 109
ASP A 188
ASP A 178
 ZN  A1289 (-3.2A)
ZN  A1287 (-3.3A)
None
ZN  A1288 (-3.1A)
 1.30A 4blvA-2x7vA:
undetectable		 4blvA-2x7vA:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.43A 5eeuB-2x7vA:
undetectable
5eeuC-2x7vA:
undetectable		 5eeuB-2x7vA:
13.50
5eeuC-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.39A 5eeuG-2x7vA:
undetectable
5eeuH-2x7vA:
undetectable		 5eeuG-2x7vA:
13.50
5eeuH-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eeuN-2x7vA:
undetectable
5eeuO-2x7vA:
undetectable		 5eeuN-2x7vA:
13.50
5eeuO-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 5eeuP-2x7vA:
undetectable
5eeuQ-2x7vA:
undetectable		 5eeuP-2x7vA:
13.50
5eeuQ-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 5eeuR-2x7vA:
undetectable
5eeuS-2x7vA:
undetectable		 5eeuR-2x7vA:
13.50
5eeuS-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eeuS-2x7vA:
undetectable
5eeuT-2x7vA:
undetectable		 5eeuS-2x7vA:
13.50
5eeuT-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.39A 5eeuT-2x7vA:
undetectable
5eeuU-2x7vA:
undetectable		 5eeuT-2x7vA:
13.50
5eeuU-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 5eeuU-2x7vA:
undetectable
5eeuV-2x7vA:
undetectable		 5eeuU-2x7vA:
13.50
5eeuV-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.42A 5eevB-2x7vA:
undetectable
5eevC-2x7vA:
undetectable		 5eevB-2x7vA:
13.50
5eevC-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.39A 5eevG-2x7vA:
undetectable
5eevH-2x7vA:
undetectable		 5eevG-2x7vA:
13.50
5eevH-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eevN-2x7vA:
undetectable
5eevO-2x7vA:
undetectable		 5eevN-2x7vA:
13.50
5eevO-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 5eevP-2x7vA:
undetectable
5eevQ-2x7vA:
undetectable		 5eevP-2x7vA:
13.50
5eevQ-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 5eevR-2x7vA:
undetectable
5eevS-2x7vA:
undetectable		 5eevR-2x7vA:
13.50
5eevS-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eevS-2x7vA:
undetectable
5eevT-2x7vA:
undetectable		 5eevS-2x7vA:
13.50
5eevT-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.39A 5eevT-2x7vA:
undetectable
5eevU-2x7vA:
undetectable		 5eevT-2x7vA:
13.50
5eevU-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 5eevU-2x7vA:
undetectable
5eevV-2x7vA:
undetectable		 5eevU-2x7vA:
13.50
5eevV-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.42A 5eewB-2x7vA:
undetectable
5eewC-2x7vA:
undetectable		 5eewB-2x7vA:
13.50
5eewC-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.39A 5eewG-2x7vA:
undetectable
5eewH-2x7vA:
undetectable		 5eewG-2x7vA:
13.50
5eewH-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eewN-2x7vA:
undetectable
5eewO-2x7vA:
undetectable		 5eewN-2x7vA:
13.50
5eewO-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 5eewP-2x7vA:
undetectable
5eewQ-2x7vA:
undetectable		 5eewP-2x7vA:
13.50
5eewQ-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 5eewR-2x7vA:
undetectable
5eewS-2x7vA:
undetectable		 5eewR-2x7vA:
13.50
5eewS-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5eewS-2x7vA:
undetectable
5eewT-2x7vA:
undetectable		 5eewS-2x7vA:
13.50
5eewT-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.39A 5eewT-2x7vA:
undetectable
5eewU-2x7vA:
undetectable		 5eewT-2x7vA:
13.50
5eewU-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eewU-2x7vA:
undetectable
5eewV-2x7vA:
undetectable		 5eewU-2x7vA:
13.50
5eewV-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.42A 5eexB-2x7vA:
undetectable
5eexC-2x7vA:
undetectable		 5eexB-2x7vA:
13.50
5eexC-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.38A 5eexG-2x7vA:
undetectable
5eexH-2x7vA:
undetectable		 5eexG-2x7vA:
13.50
5eexH-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eexN-2x7vA:
undetectable
5eexO-2x7vA:
undetectable		 5eexN-2x7vA:
13.50
5eexO-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.34A 5eexP-2x7vA:
undetectable
5eexQ-2x7vA:
undetectable		 5eexP-2x7vA:
13.50
5eexQ-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5eexQ-2x7vA:
undetectable
5eexR-2x7vA:
undetectable		 5eexQ-2x7vA:
13.50
5eexR-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 5eexR-2x7vA:
undetectable
5eexS-2x7vA:
undetectable		 5eexR-2x7vA:
13.50
5eexS-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5eexS-2x7vA:
undetectable
5eexT-2x7vA:
undetectable		 5eexS-2x7vA:
13.50
5eexT-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.39A 5eexT-2x7vA:
undetectable
5eexU-2x7vA:
undetectable		 5eexT-2x7vA:
13.50
5eexU-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eexU-2x7vA:
undetectable
5eexV-2x7vA:
undetectable		 5eexU-2x7vA:
13.50
5eexV-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.41A 5eeyB-2x7vA:
undetectable
5eeyC-2x7vA:
undetectable		 5eeyB-2x7vA:
13.50
5eeyC-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.38A 5eeyG-2x7vA:
undetectable
5eeyH-2x7vA:
undetectable		 5eeyG-2x7vA:
13.50
5eeyH-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eeyN-2x7vA:
undetectable
5eeyO-2x7vA:
undetectable		 5eeyN-2x7vA:
13.50
5eeyO-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.34A 5eeyP-2x7vA:
undetectable
5eeyQ-2x7vA:
undetectable		 5eeyP-2x7vA:
13.50
5eeyQ-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5eeyQ-2x7vA:
undetectable
5eeyR-2x7vA:
undetectable		 5eeyQ-2x7vA:
13.50
5eeyR-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eeyR-2x7vA:
undetectable
5eeyS-2x7vA:
undetectable		 5eeyR-2x7vA:
13.50
5eeyS-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5eeyS-2x7vA:
undetectable
5eeyT-2x7vA:
undetectable		 5eeyS-2x7vA:
13.50
5eeyT-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.39A 5eeyT-2x7vA:
undetectable
5eeyU-2x7vA:
undetectable		 5eeyT-2x7vA:
13.50
5eeyU-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eeyU-2x7vA:
undetectable
5eeyV-2x7vA:
undetectable		 5eeyU-2x7vA:
13.50
5eeyV-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.41A 5eezB-2x7vA:
undetectable
5eezC-2x7vA:
undetectable		 5eezB-2x7vA:
13.50
5eezC-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.38A 5eezG-2x7vA:
undetectable
5eezH-2x7vA:
undetectable		 5eezG-2x7vA:
13.50
5eezH-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eezN-2x7vA:
undetectable
5eezO-2x7vA:
undetectable		 5eezN-2x7vA:
13.50
5eezO-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.34A 5eezP-2x7vA:
undetectable
5eezQ-2x7vA:
undetectable		 5eezP-2x7vA:
13.50
5eezQ-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5eezQ-2x7vA:
undetectable
5eezR-2x7vA:
undetectable		 5eezQ-2x7vA:
13.50
5eezR-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eezR-2x7vA:
undetectable
5eezS-2x7vA:
undetectable		 5eezR-2x7vA:
13.50
5eezS-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5eezS-2x7vA:
undetectable
5eezT-2x7vA:
undetectable		 5eezS-2x7vA:
13.50
5eezT-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.39A 5eezT-2x7vA:
undetectable
5eezU-2x7vA:
undetectable		 5eezT-2x7vA:
13.50
5eezU-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5eezU-2x7vA:
undetectable
5eezV-2x7vA:
undetectable		 5eezU-2x7vA:
13.50
5eezV-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.41A 5ef0B-2x7vA:
undetectable
5ef0C-2x7vA:
undetectable		 5ef0B-2x7vA:
13.50
5ef0C-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.38A 5ef0G-2x7vA:
undetectable
5ef0H-2x7vA:
undetectable		 5ef0G-2x7vA:
13.50
5ef0H-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef0N-2x7vA:
undetectable
5ef0O-2x7vA:
undetectable		 5ef0N-2x7vA:
13.50
5ef0O-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.34A 5ef0P-2x7vA:
undetectable
5ef0Q-2x7vA:
undetectable		 5ef0P-2x7vA:
13.50
5ef0Q-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef0Q-2x7vA:
undetectable
5ef0R-2x7vA:
undetectable		 5ef0Q-2x7vA:
13.50
5ef0R-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 5ef0R-2x7vA:
undetectable
5ef0S-2x7vA:
undetectable		 5ef0R-2x7vA:
13.50
5ef0S-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef0S-2x7vA:
undetectable
5ef0T-2x7vA:
undetectable		 5ef0S-2x7vA:
13.50
5ef0T-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.39A 5ef0T-2x7vA:
undetectable
5ef0U-2x7vA:
undetectable		 5ef0T-2x7vA:
13.50
5ef0U-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5ef0U-2x7vA:
undetectable
5ef0V-2x7vA:
undetectable		 5ef0U-2x7vA:
13.50
5ef0V-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.41A 5ef1B-2x7vA:
undetectable
5ef1C-2x7vA:
undetectable		 5ef1B-2x7vA:
13.50
5ef1C-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.38A 5ef1G-2x7vA:
undetectable
5ef1H-2x7vA:
undetectable		 5ef1G-2x7vA:
13.50
5ef1H-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef1N-2x7vA:
undetectable
5ef1O-2x7vA:
undetectable		 5ef1N-2x7vA:
13.50
5ef1O-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.34A 5ef1P-2x7vA:
undetectable
5ef1Q-2x7vA:
undetectable		 5ef1P-2x7vA:
13.50
5ef1Q-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 5ef1Q-2x7vA:
undetectable
5ef1R-2x7vA:
undetectable		 5ef1Q-2x7vA:
13.50
5ef1R-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5ef1R-2x7vA:
undetectable
5ef1S-2x7vA:
undetectable		 5ef1R-2x7vA:
13.50
5ef1S-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 5ef1S-2x7vA:
undetectable
5ef1T-2x7vA:
undetectable		 5ef1S-2x7vA:
13.50
5ef1T-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.39A 5ef1T-2x7vA:
undetectable
5ef1U-2x7vA:
undetectable		 5ef1T-2x7vA:
13.50
5ef1U-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef1U-2x7vA:
undetectable
5ef1V-2x7vA:
undetectable		 5ef1U-2x7vA:
13.50
5ef1V-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.41A 5ef2B-2x7vA:
undetectable
5ef2C-2x7vA:
undetectable		 5ef2B-2x7vA:
13.50
5ef2C-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.38A 5ef2G-2x7vA:
undetectable
5ef2H-2x7vA:
undetectable		 5ef2G-2x7vA:
13.50
5ef2H-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef2N-2x7vA:
undetectable
5ef2O-2x7vA:
undetectable		 5ef2N-2x7vA:
13.50
5ef2O-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.34A 5ef2P-2x7vA:
undetectable
5ef2Q-2x7vA:
undetectable		 5ef2P-2x7vA:
13.50
5ef2Q-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 5ef2Q-2x7vA:
undetectable
5ef2R-2x7vA:
undetectable		 5ef2Q-2x7vA:
13.50
5ef2R-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5ef2R-2x7vA:
undetectable
5ef2S-2x7vA:
undetectable		 5ef2R-2x7vA:
13.50
5ef2S-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef2S-2x7vA:
undetectable
5ef2T-2x7vA:
undetectable		 5ef2S-2x7vA:
13.50
5ef2T-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 5ef2T-2x7vA:
undetectable
5ef2U-2x7vA:
undetectable		 5ef2T-2x7vA:
13.50
5ef2U-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef2U-2x7vA:
undetectable
5ef2V-2x7vA:
undetectable		 5ef2U-2x7vA:
13.50
5ef2V-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.41A 5ef3B-2x7vA:
undetectable
5ef3C-2x7vA:
undetectable		 5ef3B-2x7vA:
13.50
5ef3C-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 THR A 261
GLY A   5
HIS A 268
HIS A 215
ILE A   4
 None
None
None
ZN  A1288 (-3.3A)
None
 1.37A 5ef3G-2x7vA:
undetectable
5ef3H-2x7vA:
undetectable		 5ef3G-2x7vA:
13.50
5ef3H-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef3N-2x7vA:
undetectable
5ef3O-2x7vA:
undetectable		 5ef3N-2x7vA:
13.50
5ef3O-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.33A 5ef3P-2x7vA:
undetectable
5ef3Q-2x7vA:
undetectable		 5ef3P-2x7vA:
13.50
5ef3Q-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 9 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 5ef3Q-2x7vA:
undetectable
5ef3R-2x7vA:
undetectable		 5ef3Q-2x7vA:
13.50
5ef3R-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.37A 5ef3R-2x7vA:
undetectable
5ef3S-2x7vA:
undetectable		 5ef3R-2x7vA:
13.50
5ef3S-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.35A 5ef3S-2x7vA:
undetectable
5ef3T-2x7vA:
undetectable		 5ef3S-2x7vA:
13.50
5ef3T-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.38A 5ef3T-2x7vA:
undetectable
5ef3U-2x7vA:
undetectable		 5ef3T-2x7vA:
13.50
5ef3U-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		5 / 10 GLY A   5
HIS A 268
HIS A 215
ILE A   4
THR A 261
 None
None
ZN  A1288 (-3.3A)
None
None
 1.36A 5ef3U-2x7vA:
undetectable
5ef3V-2x7vA:
undetectable		 5ef3U-2x7vA:
13.50
5ef3V-2x7vA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESK_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 4 ALA A 174
PRO A 256
LEU A 216
HIS A 215
 None
None
None
ZN  A1288 (-3.3A)
 1.36A 5eskA-2x7vA:
undetectable		 5eskA-2x7vA:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_C_MMSC516_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 8 HIS A 230
ASN A 217
GLY A 182
SER A 147
 ZN  A1289 (-3.2A)
ZN  A1288 ( 4.9A)
None
None
 1.03A 5m8rC-2x7vA:
undetectable		 5m8rC-2x7vA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 4 ASP A 178
HIS A 181
HIS A 109
HIS A 215
 ZN  A1288 (-3.1A)
ZN  A1289 ( 3.3A)
ZN  A1287 (-3.3A)
ZN  A1288 (-3.3A)
 1.02A 5ncdD-2x7vA:
3.4		 5ncdD-2x7vA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 6 ASP A 178
HIS A 181
HIS A 109
HIS A 215
 ZN  A1288 (-3.1A)
ZN  A1289 ( 3.3A)
ZN  A1287 (-3.3A)
ZN  A1288 (-3.3A)
 1.01A 5nelB-2x7vA:
4.3
5nelC-2x7vA:
3.4		 5nelB-2x7vA:
21.50
5nelC-2x7vA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 6 HIS A  69
ASP A 178
HIS A 181
HIS A 215
 ZN  A1287 (-3.5A)
ZN  A1288 (-3.1A)
ZN  A1289 ( 3.3A)
ZN  A1288 (-3.3A)
 1.07A 5nelB-2x7vA:
4.3
5nelC-2x7vA:
3.4		 5nelB-2x7vA:
21.50
5nelC-2x7vA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BC9_A_ETSA302_2
(CARBONIC ANHYDRASE 2)		 2x7v PROBABLE
ENDONUCLEASE 4
(Thermotoga
maritima) 		4 / 5 HIS A 109
GLU A  94
LEU A 133
VAL A 132
 ZN  A1287 (-3.3A)
None
None
None
 1.06A 6bc9A-2x7vA:
undetectable		 6bc9A-2x7vA:
13.17