SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x8k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 2x8k HYPOTHETICAL PROTEIN
19.1
(Bacillus
phage
SPP1) 		3 / 3 TYR A 137
ARG A 109
GLN A 132
 None
 1.01A 1tw4A-2x8kA:
undetectable		 1tw4A-2x8kA:
19.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_B_SAMB300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2x8k HYPOTHETICAL PROTEIN
19.1
(Bacillus
phage
SPP1) 		3 / 3 TYR A 130
ASP A  93
ASP A  91
 None
 0.59A 3ou7B-2x8kA:
undetectable		 3ou7B-2x8kA:
22.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E0F_A_RBFA301_2
(RIBOFLAVIN SYNTHASE
SUBUNIT ALPHA)		 2x8k HYPOTHETICAL PROTEIN
19.1
(Bacillus
phage
SPP1) 		3 / 3 LYS A 251
THR A 249
ILE A 203
 None
 0.82A 4e0fB-2x8kA:
1.9		 4e0fB-2x8kA:
25.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2x8k HYPOTHETICAL PROTEIN
19.1
(Bacillus
phage
SPP1) 		4 / 8 ASP A 133
ASN A 161
CYH A 205
GLU A 207
 None
 1.13A 4feuF-2x8kA:
2.3		 4feuF-2x8kA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2x8k HYPOTHETICAL PROTEIN
19.1
(Bacillus
phage
SPP1) 		4 / 8 ASP A 133
ASN A 161
CYH A 205
GLU A 207
 None
 1.15A 4gkhB-2x8kA:
undetectable		 4gkhB-2x8kA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2x8k HYPOTHETICAL PROTEIN
19.1
(Bacillus
phage
SPP1) 		4 / 8 ASP A 133
ASN A 161
CYH A 205
GLU A 207
 None
 0.95A 4gkhD-2x8kA:
undetectable		 4gkhD-2x8kA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 2x8k HYPOTHETICAL PROTEIN
19.1
(Bacillus
phage
SPP1) 		4 / 8 ASP A 133
ASN A 161
CYH A 205
GLU A 207
 None
 1.16A 4gkiC-2x8kA:
undetectable		 4gkiC-2x8kA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CSW_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 2x8k HYPOTHETICAL PROTEIN
19.1
(Bacillus
phage
SPP1) 		3 / 3 PHE A 129
ILE A  96
ASP A 133
 None
 0.75A 5cswA-2x8kA:
2.4		 5cswA-2x8kA:
21.40