SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 2x9a ATTACHMENT PROTEIN
G3P
(Escherichia
virus
If1) 		4 / 5 THR A  16
GLY A  53
ASN A  52
TYR A  45
 None
 1.22A 3u8qA-2x9aA:
undetectable		 3u8qA-2x9aA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 2x9a MEMBRANE SPANNING
PROTEIN, REQUIRED
FOR OUTER MEMBRANE
INTEGRITY
(Escherichia
coli) 		3 / 3 ASP B 417
ARG B 365
PRO B 415
 None
 1.03A 4wanC-2x9aB:
undetectable		 4wanC-2x9aB:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERG_B_SAMB401_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
CATALYTIC SUBUNIT
TRM61)		 2x9a ATTACHMENT PROTEIN
G3P
MEMBRANE SPANNING
PROTEIN, REQUIRED
FOR OUTER MEMBRANE
INTEGRITY
(Escherichia
virus
If1;
Escherichia
coli) 		4 / 7 GLY A  42
GLY A  44
ASP A  14
ASP B 417
 None
 0.79A 5ergB-2x9aA:
undetectable		 5ergB-2x9aA:
9.14