SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2x9q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_A_J01A1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 2x9q CYCLODIPEPTIDE
SYNTHETASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 144
ALA A 140
TYR A 126
THR A 118
TYR A 229
 None
 1.13A 2japA-2x9qA:
3.2		 2japA-2x9qA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_B_J01B1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 2x9q CYCLODIPEPTIDE
SYNTHETASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 144
ALA A 140
TYR A 126
THR A 118
TYR A 229
 None
 1.13A 2japB-2x9qA:
3.1		 2japB-2x9qA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_C_J01C1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 2x9q CYCLODIPEPTIDE
SYNTHETASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 144
ALA A 140
TYR A 126
THR A 118
TYR A 229
 None
 1.11A 2japC-2x9qA:
3.2		 2japC-2x9qA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JAP_D_J01D1249_1
(CLAVALDEHYDE
DEHYDROGENASE)		 2x9q CYCLODIPEPTIDE
SYNTHETASE
(Mycobacterium
tuberculosis) 		5 / 12 ILE A 144
ALA A 140
TYR A 126
THR A 118
TYR A 229
 None
 1.12A 2japD-2x9qA:
3.2		 2japD-2x9qA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HOJ_A_ACTA303_0
(REGF PROTEIN)		 2x9q CYCLODIPEPTIDE
SYNTHETASE
(Mycobacterium
tuberculosis) 		4 / 5 VAL A 116
ARG A 168
MET A 170
GLU A 172
 None
 1.32A 4hojA-2x9qA:
undetectable		 4hojA-2x9qA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_A_DGXA1107_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2x9q CYCLODIPEPTIDE
SYNTHETASE
(Mycobacterium
tuberculosis) 		4 / 4 ASN A 251
VAL A 116
THR A 240
ILE A 243
 None
 1.43A 4retA-2x9qA:
3.6		 4retA-2x9qA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RET_C_DGXC2005_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 2x9q CYCLODIPEPTIDE
SYNTHETASE
(Mycobacterium
tuberculosis) 		4 / 4 ASN A 251
VAL A 116
THR A 240
ILE A 243
 None
 1.43A 4retC-2x9qA:
4.0		 4retC-2x9qA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 2x9q CYCLODIPEPTIDE
SYNTHETASE
(Mycobacterium
tuberculosis) 		4 / 7 ILE A 230
LEU A 259
MET A 262
LEU A 263
 None
 0.80A 5u4sA-2x9qA:
2.9		 5u4sA-2x9qA:
22.41