SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xa3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXT_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-3 GRAFT VHH)		 2xa3 LLAMA HEAVY CHAIN
ANTIBODY D7
(Lama
glama) 		6 / 12 LEU A   4
SER A  29
MET A  34
VAL A  78
ALA A  94
TYR A 102
 None
SO4  A1114 (-2.7A)
None
None
None
None
 0.78A 3qxtB-2xa3A:
21.2		 3qxtB-2xa3A:
69.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_A_MTXA2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 2xa3 LLAMA HEAVY CHAIN
ANTIBODY D7
(Lama
glama) 		6 / 12 SER A  29
MET A  34
ASN A  73
VAL A  78
ALA A  94
TYR A 102
 SO4  A1114 (-2.7A)
None
None
None
None
None
 0.90A 3qxvA-2xa3A:
21.0		 3qxvA-2xa3A:
69.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_B_MTXB2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 2xa3 LLAMA HEAVY CHAIN
ANTIBODY D7
(Lama
glama) 		5 / 12 SER A  29
MET A  34
VAL A  78
ALA A  94
TYR A 102
 SO4  A1114 (-2.7A)
None
None
None
None
 0.76A 3qxvB-2xa3A:
20.9		 3qxvB-2xa3A:
69.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_C_MTXC2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 2xa3 LLAMA HEAVY CHAIN
ANTIBODY D7
(Lama
glama) 		5 / 11 SER A  29
MET A  34
ASN A  73
VAL A  78
ALA A  94
 SO4  A1114 (-2.7A)
None
None
None
None
 0.80A 3qxvC-2xa3A:
21.2		 3qxvC-2xa3A:
69.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_D_MTXD2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 2xa3 LLAMA HEAVY CHAIN
ANTIBODY D7
(Lama
glama) 		5 / 12 SER A  29
MET A  34
VAL A  78
ALA A  94
TYR A 102
 SO4  A1114 (-2.7A)
None
None
None
None
 0.68A 3qxvD-2xa3A:
20.8		 3qxvD-2xa3A:
69.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3QXV_E_MTXE2000_1
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 2xa3 LLAMA HEAVY CHAIN
ANTIBODY D7
(Lama
glama) 		5 / 12 SER A  29
MET A  34
VAL A  78
ALA A  94
TYR A 102
 SO4  A1114 (-2.7A)
None
None
None
None
 0.77A 3qxvE-2xa3A:
17.2		 3qxvE-2xa3A:
69.77