SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xax'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DVT_A_FLPA125_1 (TRANSTHYRETIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 8	LYS A 575 ALA A 574 LEU A 489 LEU A 513	None	0.96A	1dvtA-2xaxA: undetectable 1dvtB-2xaxA: undetectable	1dvtA-2xaxA: 10.30 1dvtB-2xaxA: 10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBY_A_9CRA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	1.01A	1fbyA-2xaxA: undetectable	1fbyA-2xaxA: 17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FBY_B_9CRB1500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	0.99A	1fbyB-2xaxA: undetectable	1fbyB-2xaxA: 17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LWE_A_NVPA999_1 (HIV-1 REVERSE TRANSCRIPTASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 7	LEU A 669 TYR A 531 TYR A 678 GLY A 674	None	1.00A	1lweA-2xaxA: undetectable	1lweA-2xaxA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1M4I_A_KANA500_1 (AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERA SE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 8	ASP A 586 GLY A 683 ASP A 418 THR A 422	None	0.75A	1m4iA-2xaxA: undetectable	1m4iA-2xaxA: 14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1Q23_E_FUAE706_1 (CHLORAMPHENICOL ACETYLTRANSFERASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 10	THR A 632 TYR A 531 LEU A 619 PHE A 544 VAL A 517	None	1.42A	1q23E-2xaxA: undetectable	1q23E-2xaxA: 14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R30_A_SAMA501_0 (BIOTIN SYNTHASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	GLY A 674 ASN A 698 ILE A 635 LEU A 619 LEU A 729	None None None None NIY A 730 ( 4.0A)	1.07A	1r30A-2xaxA: 2.8	1r30A-2xaxA: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1R30_B_SAMB501_0 (BIOTIN SYNTHASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	GLY A 674 ASN A 698 ILE A 635 LEU A 619 LEU A 729	None None None None NIY A 730 ( 4.0A)	1.07A	1r30B-2xaxA: 2.7	1r30B-2xaxA: 19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RLB_F_REAF177_1 (RETINOL BINDING PROTEIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 11	LEU A 172 ALA A 147 VAL A 176 LEU A 180 LEU A 207	None	1.14A	1rlbF-2xaxA: undetectable	1rlbF-2xaxA: 12.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S1X_A_NVPA999_1 (REVERSE TRANSCRIPTASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 8	LEU A 669 TYR A 531 TYR A 678 GLY A 674	None	0.98A	1s1xA-2xaxA: undetectable	1s1xA-2xaxA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9P_C_DESC500_1 (ESTROGEN-RELATED RECEPTOR GAMMA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	LEU A 478 LEU A 481 LEU A 484 ALA A 485 ILE A 547	None	1.05A	1s9pC-2xaxA: undetectable	1s9pC-2xaxA: 13.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TW4_B_CHDB1130_0 (FATTY ACID-BINDING PROTEIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	TYR A 306 LEU A 401 ILE A 412 THR A 409 ILE A 279	None	1.08A	1tw4B-2xaxA: undetectable	1tw4B-2xaxA: 12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_E_9CRE1500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	1.01A	1xdkE-2xaxA: undetectable	1xdkE-2xaxA: 17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XIU_A_9CRA201_1 (RXR-LIKE PROTEIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	1.01A	1xiuA-2xaxA: undetectable	1xiuA-2xaxA: 17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_B_RBFB301_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 459 LEU A 227 ALA A 503 SER A 224 LEU A 464	None	1.13A	2a58A-2xaxA: undetectable 2a58B-2xaxA: undetectable	2a58A-2xaxA: 13.39 2a58B-2xaxA: 13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_C_RBFC302_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 459 LEU A 227 ALA A 503 SER A 224 LEU A 464	None	1.14A	2a58B-2xaxA: undetectable 2a58C-2xaxA: undetectable	2a58B-2xaxA: 13.39 2a58C-2xaxA: 13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A58_E_RBFE304_1 (6,7-DIMETHYL-8-RIBIT YLLUMAZINE SYNTHASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 459 LEU A 227 ALA A 503 SER A 224 LEU A 464	None	1.13A	2a58D-2xaxA: undetectable 2a58E-2xaxA: undetectable	2a58D-2xaxA: 13.39 2a58E-2xaxA: 13.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2OUZ_A_C3DA999_0 (ESTROGEN RECEPTOR)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	LEU A 551 LEU A 611 LEU A 578 GLY A 610 HIS A 609	None	1.08A	2ouzA-2xaxA: undetectable	2ouzA-2xaxA: 15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDY_A_HCYA1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	PHE A 285 ILE A 237 ASN A 238 SER A 241 PHE A 281	None	1.36A	2vdyA-2xaxA: undetectable	2vdyA-2xaxA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDY_A_HCYA1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	THR A 276 PHE A 281 ILE A 237 ASN A 238 PHE A 274	None	1.30A	2vdyA-2xaxA: undetectable	2vdyA-2xaxA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VDY_B_HCYB1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	THR A 276 PHE A 281 ILE A 237 ASN A 238 PHE A 274	None	1.25A	2vdyB-2xaxA: undetectable	2vdyB-2xaxA: 19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XCT_G_CPFG1020_1 (DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	ARG A 262 GLY A 265 SER A 315	None	0.63A	2xctB-2xaxA: undetectable	2xctB-2xaxA: 22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AX7_A_SALA1336_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 8	GLU A 458 SER A 614 THR A 571 ALA A 431	None	0.98A	3ax7A-2xaxA: undetectable	3ax7A-2xaxA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AX9_A_SALA1341_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 8	GLU A 458 SER A 614 THR A 571 ALA A 431	None	0.96A	3ax9A-2xaxA: undetectable	3ax9A-2xaxA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FAL_C_REAC501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 10	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	1.02A	3falC-2xaxA: undetectable	3falC-2xaxA: 17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GWU_A_SREA801_1 (TRANSPORTER)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	LEU A 481 LEU A 484 ALA A 488 PHE A 196 LEU A 207	None	1.16A	3gwuA-2xaxA: undetectable	3gwuA-2xaxA: 21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NS1_L_PM6L1_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 8	GLU A 458 SER A 614 THR A 571 ALA A 431	None	0.93A	3ns1L-2xaxA: undetectable	3ns1L-2xaxA: 22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OAP_A_9CRA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	6 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81 ILE A 53	None	1.21A	3oapA-2xaxA: undetectable	3oapA-2xaxA: 16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3R9T_B_BEZB264_0 (ECHA1_1)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 7	ILE A 22 LEU A 26 ALA A 65 ALA A 66	None	0.90A	3r9tB-2xaxA: 1.9	3r9tB-2xaxA: 16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3U5J_A_08HA1_1 (BROMODOMAIN-CONTAINI NG PROTEIN 4)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 7	LEU A 719 ASN A 416 ILE A 339 MET A 308	None	1.04A	3u5jA-2xaxA: 2.9	3u5jA-2xaxA: 9.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UG8_A_IMNA2001_2 (ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	TYR A 699 GLU A 667 TYR A 531	None	0.76A	3ug8A-2xaxA: undetectable	3ug8A-2xaxA: 16.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UVV_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 ALA A 81 ILE A 53	None	1.20A	3uvvB-2xaxA: undetectable	3uvvB-2xaxA: 16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VW1_D_CVID301_1 (PUTATIVE REGULATORY PROTEIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	TYR A 94 MET A 131 LEU A 175	None	0.91A	3vw1D-2xaxA: undetectable	3vw1D-2xaxA: 13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZQT_A_30ZA1920_1 (ANDROGEN RECEPTOR)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 6	PRO A 673 GLY A 674 ASN A 675 GLU A 671	None	0.80A	3zqtA-2xaxA: undetectable	3zqtA-2xaxA: 16.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_A_HCYA1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	THR A 276 PHE A 281 ILE A 237 ASN A 238 PHE A 274	None	1.23A	4c49A-2xaxA: undetectable	4c49A-2xaxA: 19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_B_HCYB1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	PHE A 285 ILE A 237 ASN A 238 SER A 241 PHE A 281	None	1.42A	4c49B-2xaxA: undetectable	4c49B-2xaxA: 19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_B_HCYB1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	THR A 276 PHE A 281 ILE A 237 ASN A 238 PHE A 274	None	1.28A	4c49B-2xaxA: undetectable	4c49B-2xaxA: 19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_C_HCYC1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	PHE A 285 ILE A 237 ASN A 238 SER A 241 PHE A 281	None	1.38A	4c49C-2xaxA: undetectable	4c49C-2xaxA: 19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_C_HCYC1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	THR A 276 PHE A 281 ILE A 237 ASN A 238 PHE A 274	None	1.28A	4c49C-2xaxA: undetectable	4c49C-2xaxA: 19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E0F_A_RBFA301_2 (RIBOFLAVIN SYNTHASE SUBUNIT ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	LYS A 716 THR A 720 ILE A 590	None	0.68A	4e0fB-2xaxA: undetectable	4e0fB-2xaxA: 14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EAH_F_ACTF402_0 (ACTIN, ALPHA SKELETAL MUSCLE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	PHE A 87 ASP A 140 ARG A 90	None	0.70A	4eahF-2xaxA: undetectable	4eahF-2xaxA: 20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EAH_G_ACTG401_0 (ACTIN, ALPHA SKELETAL MUSCLE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	PHE A 87 ASP A 140 ARG A 90	None	0.69A	4eahG-2xaxA: undetectable	4eahG-2xaxA: 20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IIZ_A_LURA201_1 (TRANSTHYRETIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	LYS A 204 LEU A 481 ALA A 199	None	0.85A	4iizA-2xaxA: undetectable	4iizA-2xaxA: 9.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4K6I_A_9RAA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	0.96A	4k6iA-2xaxA: undetectable	4k6iA-2xaxA: 16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M5M_A_DX4A401_0 (2-AMINO-4-HYDROXY-6- HYDROXYMETHYLDIHYDRO PTERIDINE PYROPHOSPHOKINASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 8	GLY A 470 THR A 632 TYR A 522 ASN A 519	None	1.20A	4m5mA-2xaxA: undetectable	4m5mA-2xaxA: 10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NQA_H_9CRH501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 65 LEU A 84 ALA A 81 ILE A 53	None	1.04A	4nqaH-2xaxA: undetectable	4nqaH-2xaxA: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NQA_H_9CRH501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 ALA A 81 ILE A 53	None	1.08A	4nqaH-2xaxA: undetectable	4nqaH-2xaxA: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R1Z_B_AERB601_1 (CYP17A1 PROTEIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 7	ALA A 243 GLY A 457 ALA A 502 GLU A 458	None	0.78A	4r1zB-2xaxA: undetectable	4r1zB-2xaxA: 22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R29_D_SAMD301_1 (UNCHARACTERIZED PROTEIN)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	ARG A 72 GLU A 671 TYR A 659	None	0.76A	4r29D-2xaxA: undetectable	4r29D-2xaxA: 15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4R3A_B_RBFB402_2 (BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ALA A 302 LEU A 438 ALA A 243 ILE A 244 GLY A 300	None	1.02A	4r3aB-2xaxA: undetectable	4r3aB-2xaxA: 20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X61_A_SAMA701_0 (PROTEIN ARGININE N-METHYLTRANSFERASE 5)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	GLY A 516 PRO A 208 LEU A 464 ASN A 468 LEU A 619	None	1.31A	4x61A-2xaxA: 2.4	4x61A-2xaxA: 22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5FSA_A_X2NA590_2 (CYP51 VARIANT1)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	PRO A 425 ILE A 414 SER A 614	None	0.78A	5fsaA-2xaxA: undetectable	5fsaA-2xaxA: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UAN_A_9CRA503_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	1.02A	5uanA-2xaxA: undetectable	5uanA-2xaxA: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X66_A_MTXA402_1 (THYMIDYLATE SYNTHASE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 58 LEU A 84 TYR A 145 ALA A 67 ASP A 20	None	1.05A	5x66A-2xaxA: undetectable 5x66B-2xaxA: undetectable	5x66A-2xaxA: 17.56 5x66B-2xaxA: 17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YW0_A_ACTA411_0 (UNCHARACTERIZED PROTEIN KDOO)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	LYS A 381 LEU A 378 ARG A 377	None	0.90A	5yw0A-2xaxA: undetectable	5yw0A-2xaxA: 18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	0.96A	5z12B-2xaxA: undetectable	5z12B-2xaxA: 7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_C_9CRC501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	0.98A	5z12C-2xaxA: undetectable	5z12C-2xaxA: 7.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5Y_D_9CRD501_0 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	1.00A	6a5yD-2xaxA: undetectable	6a5yD-2xaxA: 7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6A5Z_L_9CRL501_0 (RETINOIC ACID RECEPTOR RXR-ALPHA)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	5 / 12	ILE A 62 ALA A 66 ALA A 65 LEU A 84 ALA A 81	None	0.95A	6a5zL-2xaxA: undetectable	6a5zL-2xaxA: 7.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DWN_A_AQ4A602_1 (CYTOCHROME P450 1A1)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 5	ILE A 606 SER A 605 ALA A 554 LEU A 616	None	0.96A	6dwnA-2xaxA: undetectable	6dwnA-2xaxA: 6.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_D_ADND502_1 (ADENOSYLHOMOCYSTEINA SE)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	3 / 3	LEU A 355 ASN A 340 LEU A 364	None	0.73A	6exiD-2xaxA: 3.3	6exiD-2xaxA: 7.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HUO_D_08HD501_0 (GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOB UTYRIC ACID RECEPTOR SUBUNIT ALPHA-1 GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2)	2xax	RIBONUCLEOSIDE-DIPHO SPHATE REDUCTASE 1 SUBUNIT ALPHA (Escherichia coli)	4 / 8	TYR A 103 PHE A 128 VAL A 110 TYR A 115	None	0.66A	6huoC-2xaxA: undetectable 6huoD-2xaxA: undetectable	6huoC-2xaxA: 7.63 6huoD-2xaxA: 6.96

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DVT_A_FLPA125_1","TRANSTHYRETIN;TRANSTHYRETIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"LYS A 575;ALA A 574;LEU A 489;LEU A 513","None","0.96A","1dvtA-2xaxA:undetectable;1dvtB-2xaxA:undetectable","1dvtA-2xaxA:10.30;1dvtB-2xaxA:10.30"],["1FBY_A_9CRA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","1.01A","1fbyA-2xaxA:undetectable","1fbyA-2xaxA:17.30"],["1FBY_B_9CRB1500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","0.99A","1fbyB-2xaxA:undetectable","1fbyB-2xaxA:17.30"],["1LWE_A_NVPA999_1","HIV-1 REVERSE TRANSCRIPTASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"LEU A 669;TYR A 531;TYR A 678;GLY A 674","None","1.00A","1lweA-2xaxA:undetectable","1lweA-2xaxA:23.21"],["1M4I_A_KANA500_1","AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"ASP A 586;GLY A 683;ASP A 418;THR A 422","None","0.75A","1m4iA-2xaxA:undetectable","1m4iA-2xaxA:14.33"],["1Q23_E_FUAE706_1","CHLORAMPHENICOL ACETYLTRANSFERASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"THR A 632;TYR A 531;LEU A 619;PHE A 544;VAL A 517","None","1.42A","1q23E-2xaxA:undetectable","1q23E-2xaxA:14.51"],["1R30_A_SAMA501_0","BIOTIN SYNTHASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"GLY A 674;ASN A 698;ILE A 635;LEU A 619;LEU A 729","None;None;None;None;NIY A 730 ( 4.0A)","1.07A","1r30A-2xaxA:2.8","1r30A-2xaxA:19.20"],["1R30_B_SAMB501_0","BIOTIN SYNTHASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"GLY A 674;ASN A 698;ILE A 635;LEU A 619;LEU A 729","None;None;None;None;NIY A 730 ( 4.0A)","1.07A","1r30B-2xaxA:2.7","1r30B-2xaxA:19.20"],["1RLB_F_REAF177_1","RETINOL BINDING PROTEIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"LEU A 172;ALA A 147;VAL A 176;LEU A 180;LEU A 207","None","1.14A","1rlbF-2xaxA:undetectable","1rlbF-2xaxA:12.21"],["1S1X_A_NVPA999_1","REVERSE TRANSCRIPTASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"LEU A 669;TYR A 531;TYR A 678;GLY A 674","None","0.98A","1s1xA-2xaxA:undetectable","1s1xA-2xaxA:23.21"],["1S9P_C_DESC500_1","ESTROGEN-RELATED RECEPTOR GAMMA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"LEU A 478;LEU A 481;LEU A 484;ALA A 485;ILE A 547","None","1.05A","1s9pC-2xaxA:undetectable","1s9pC-2xaxA:13.69"],["1TW4_B_CHDB1130_0","FATTY ACID-BINDING PROTEIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"TYR A 306;LEU A 401;ILE A 412;THR A 409;ILE A 279","None","1.08A","1tw4B-2xaxA:undetectable","1tw4B-2xaxA:12.12"],["1XDK_E_9CRE1500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","1.01A","1xdkE-2xaxA:undetectable","1xdkE-2xaxA:17.30"],["1XIU_A_9CRA201_1","RXR-LIKE PROTEIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","1.01A","1xiuA-2xaxA:undetectable","1xiuA-2xaxA:17.45"],["2A58_B_RBFB301_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A 459;LEU A 227;ALA A 503;SER A 224;LEU A 464","None","1.13A","2a58A-2xaxA:undetectable;2a58B-2xaxA:undetectable","2a58A-2xaxA:13.39;2a58B-2xaxA:13.39"],["2A58_C_RBFC302_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A 459;LEU A 227;ALA A 503;SER A 224;LEU A 464","None","1.14A","2a58B-2xaxA:undetectable;2a58C-2xaxA:undetectable","2a58B-2xaxA:13.39;2a58C-2xaxA:13.39"],["2A58_E_RBFE304_1","6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE;6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A 459;LEU A 227;ALA A 503;SER A 224;LEU A 464","None","1.13A","2a58D-2xaxA:undetectable;2a58E-2xaxA:undetectable","2a58D-2xaxA:13.39;2a58E-2xaxA:13.39"],["2OUZ_A_C3DA999_0","ESTROGEN RECEPTOR","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"LEU A 551;LEU A 611;LEU A 578;GLY A 610;HIS A 609","None","1.08A","2ouzA-2xaxA:undetectable","2ouzA-2xaxA:15.64"],["2VDY_A_HCYA1384_1","CORTICOSTEROID-BINDING GLOBULIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"PHE A 285;ILE A 237;ASN A 238;SER A 241;PHE A 281","None","1.36A","2vdyA-2xaxA:undetectable","2vdyA-2xaxA:19.70"],["2VDY_A_HCYA1384_1","CORTICOSTEROID-BINDING GLOBULIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"THR A 276;PHE A 281;ILE A 237;ASN A 238;PHE A 274","None","1.30A","2vdyA-2xaxA:undetectable","2vdyA-2xaxA:19.70"],["2VDY_B_HCYB1384_1","CORTICOSTEROID-BINDING GLOBULIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"THR A 276;PHE A 281;ILE A 237;ASN A 238;PHE A 274","None","1.25A","2vdyB-2xaxA:undetectable","2vdyB-2xaxA:19.70"],["2XCT_G_CPFG1020_1","DNA GYRASE SUBUNIT B, DNA GYRASE SUBUNIT A","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"ARG A 262;GLY A 265;SER A 315","None","0.63A","2xctB-2xaxA:undetectable","2xctB-2xaxA:22.92"],["3AX7_A_SALA1336_1","XANTHINE DEHYDROGENASE\/OXIDASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"GLU A 458;SER A 614;THR A 571;ALA A 431","None","0.98A","3ax7A-2xaxA:undetectable","3ax7A-2xaxA:21.15"],["3AX9_A_SALA1341_1","XANTHINE DEHYDROGENASE\/OXIDASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"GLU A 458;SER A 614;THR A 571;ALA A 431","None","0.96A","3ax9A-2xaxA:undetectable","3ax9A-2xaxA:21.15"],["3FAL_C_REAC501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","1.02A","3falC-2xaxA:undetectable","3falC-2xaxA:17.30"],["3GWU_A_SREA801_1","TRANSPORTER","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"LEU A 481;LEU A 484;ALA A 488;PHE A 196;LEU A 207","None","1.16A","3gwuA-2xaxA:undetectable","3gwuA-2xaxA:21.73"],["3NS1_L_PM6L1_1","XANTHINE DEHYDROGENASE\/OXIDASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"GLU A 458;SER A 614;THR A 571;ALA A 431","None","0.93A","3ns1L-2xaxA:undetectable","3ns1L-2xaxA:22.45"],["3OAP_A_9CRA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",6,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81;ILE A  53","None","1.21A","3oapA-2xaxA:undetectable","3oapA-2xaxA:16.73"],["3R9T_B_BEZB264_0","ECHA1_1","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"ILE A  22;LEU A  26;ALA A  65;ALA A  66","None","0.90A","3r9tB-2xaxA:1.9","3r9tB-2xaxA:16.47"],["3U5J_A_08HA1_1","BROMODOMAIN-CONTAINING PROTEIN 4","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"LEU A 719;ASN A 416;ILE A 339;MET A 308","None","1.04A","3u5jA-2xaxA:2.9","3u5jA-2xaxA:9.87"],["3UG8_A_IMNA2001_2","ALDO-KETO REDUCTASE FAMILY 1 MEMBER C3","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"TYR A 699;GLU A 667;TYR A 531","None","0.76A","3ug8A-2xaxA:undetectable","3ug8A-2xaxA:16.84"],["3UVV_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;ALA A  81;ILE A  53","None","1.20A","3uvvB-2xaxA:undetectable","3uvvB-2xaxA:16.69"],["3VW1_D_CVID301_1","PUTATIVE REGULATORY PROTEIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"TYR A  94;MET A 131;LEU A 175","None","0.91A","3vw1D-2xaxA:undetectable","3vw1D-2xaxA:13.15"],["3ZQT_A_30ZA1920_1","ANDROGEN RECEPTOR","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"PRO A 673;GLY A 674;ASN A 675;GLU A 671","None","0.80A","3zqtA-2xaxA:undetectable","3zqtA-2xaxA:16.99"],["4C49_A_HCYA1384_1","CORTICOSTEROID-BINDING GLOBULIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"THR A 276;PHE A 281;ILE A 237;ASN A 238;PHE A 274","None","1.23A","4c49A-2xaxA:undetectable","4c49A-2xaxA:19.73"],["4C49_B_HCYB1384_1","CORTICOSTEROID-BINDING GLOBULIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"PHE A 285;ILE A 237;ASN A 238;SER A 241;PHE A 281","None","1.42A","4c49B-2xaxA:undetectable","4c49B-2xaxA:19.73"],["4C49_B_HCYB1384_1","CORTICOSTEROID-BINDING GLOBULIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"THR A 276;PHE A 281;ILE A 237;ASN A 238;PHE A 274","None","1.28A","4c49B-2xaxA:undetectable","4c49B-2xaxA:19.73"],["4C49_C_HCYC1384_1","CORTICOSTEROID-BINDING GLOBULIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"PHE A 285;ILE A 237;ASN A 238;SER A 241;PHE A 281","None","1.38A","4c49C-2xaxA:undetectable","4c49C-2xaxA:19.73"],["4C49_C_HCYC1384_1","CORTICOSTEROID-BINDING GLOBULIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"THR A 276;PHE A 281;ILE A 237;ASN A 238;PHE A 274","None","1.28A","4c49C-2xaxA:undetectable","4c49C-2xaxA:19.73"],["4E0F_A_RBFA301_2","RIBOFLAVIN SYNTHASE SUBUNIT ALPHA;RIBOFLAVIN SYNTHASE SUBUNIT ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"LYS A 716;THR A 720;ILE A 590","None","0.68A","4e0fB-2xaxA:undetectable","4e0fB-2xaxA:14.45"],["4EAH_F_ACTF402_0","ACTIN, ALPHA SKELETAL MUSCLE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"PHE A  87;ASP A 140;ARG A  90","None","0.70A","4eahF-2xaxA:undetectable","4eahF-2xaxA:20.42"],["4EAH_G_ACTG401_0","ACTIN, ALPHA SKELETAL MUSCLE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"PHE A  87;ASP A 140;ARG A  90","None","0.69A","4eahG-2xaxA:undetectable","4eahG-2xaxA:20.42"],["4IIZ_A_LURA201_1","TRANSTHYRETIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"LYS A 204;LEU A 481;ALA A 199","None","0.85A","4iizA-2xaxA:undetectable","4iizA-2xaxA:9.84"],["4K6I_A_9RAA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","0.96A","4k6iA-2xaxA:undetectable","4k6iA-2xaxA:16.73"],["4M5M_A_DX4A401_0","2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"GLY A 470;THR A 632;TYR A 522;ASN A 519","None","1.20A","4m5mA-2xaxA:undetectable","4m5mA-2xaxA:10.93"],["4NQA_H_9CRH501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  65;LEU A  84;ALA A  81;ILE A  53","None","1.04A","4nqaH-2xaxA:undetectable","4nqaH-2xaxA:18.66"],["4NQA_H_9CRH501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;ALA A  81;ILE A  53","None","1.08A","4nqaH-2xaxA:undetectable","4nqaH-2xaxA:18.66"],["4R1Z_B_AERB601_1","CYP17A1 PROTEIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"ALA A 243;GLY A 457;ALA A 502;GLU A 458","None","0.78A","4r1zB-2xaxA:undetectable","4r1zB-2xaxA:22.47"],["4R29_D_SAMD301_1","UNCHARACTERIZED PROTEIN","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"ARG A  72;GLU A 671;TYR A 659","None","0.76A","4r29D-2xaxA:undetectable","4r29D-2xaxA:15.77"],["4R3A_B_RBFB402_2","BLUE-LIGHT-ACTIVATED HISTIDINE KINASE 2","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ALA A 302;LEU A 438;ALA A 243;ILE A 244;GLY A 300","None","1.02A","4r3aB-2xaxA:undetectable","4r3aB-2xaxA:20.08"],["4X61_A_SAMA701_0","PROTEIN ARGININE N-METHYLTRANSFERASE 5","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"GLY A 516;PRO A 208;LEU A 464;ASN A 468;LEU A 619","None","1.31A","4x61A-2xaxA:2.4","4x61A-2xaxA:22.43"],["5FSA_A_X2NA590_2","CYP51 VARIANT1","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"PRO A 425;ILE A 414;SER A 614","None","0.78A","5fsaA-2xaxA:undetectable","5fsaA-2xaxA:21.14"],["5UAN_A_9CRA503_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","1.02A","5uanA-2xaxA:undetectable","5uanA-2xaxA:18.66"],["5X66_A_MTXA402_1","THYMIDYLATE SYNTHASE;THYMIDYLATE SYNTHASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  58;LEU A  84;TYR A 145;ALA A  67;ASP A  20","None","1.05A","5x66A-2xaxA:undetectable;5x66B-2xaxA:undetectable","5x66A-2xaxA:17.56;5x66B-2xaxA:17.56"],["5YW0_A_ACTA411_0","UNCHARACTERIZED PROTEIN KDOO","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"LYS A 381;LEU A 378;ARG A 377","None","0.90A","5yw0A-2xaxA:undetectable","5yw0A-2xaxA:18.69"],["5Z12_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","0.96A","5z12B-2xaxA:undetectable","5z12B-2xaxA:7.44"],["5Z12_C_9CRC501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","0.98A","5z12C-2xaxA:undetectable","5z12C-2xaxA:7.44"],["6A5Y_D_9CRD501_0","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","1.00A","6a5yD-2xaxA:undetectable","6a5yD-2xaxA:7.33"],["6A5Z_L_9CRL501_0","RETINOIC ACID RECEPTOR RXR-ALPHA","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",5,"ILE A  62;ALA A  66;ALA A  65;LEU A  84;ALA A  81","None","0.95A","6a5zL-2xaxA:undetectable","6a5zL-2xaxA:7.33"],["6DWN_A_AQ4A602_1","CYTOCHROME P450 1A1","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"ILE A 606;SER A 605;ALA A 554;LEU A 616","None","0.96A","6dwnA-2xaxA:undetectable","6dwnA-2xaxA:6.72"],["6EXI_D_ADND502_1","ADENOSYLHOMOCYSTEINASE","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",3,"LEU A 355;ASN A 340;LEU A 364","None","0.73A","6exiD-2xaxA:3.3","6exiD-2xaxA:7.04"],["6HUO_D_08HD501_0","GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1,GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT ALPHA-1;GAMMA-AMINOBUTYRIC ACID RECEPTOR SUBUNIT GAMMA-2","2xax","RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 1 SUBUNIT ALPHA","Escherichia coli",4,"TYR A 103;PHE A 128;VAL A 110;TYR A 115","None","0.66A","6huoC-2xaxA:undetectable;6huoD-2xaxA:undetectable","6huoC-2xaxA:7.63;6huoD-2xaxA:6.96"]]