SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SG9_A_SAMA301_0 (HEMK PROTEIN)	2xb3	PSBP PROTEIN (Thermosynechococ cus elongatus)	5 / 12	GLY A 90 ILE A 97 SER A 85 GLU A 82 ASN A 96	None	1.08A	1sg9A-2xb3A: undetectable	1sg9A-2xb3A: 22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y9M_A_NIOA401_1 (CASEIN KINASE II SUBUNIT ALPHA')	2xb3	PSBP PROTEIN (Thermosynechococ cus elongatus)	5 / 8	LEU A 157 VAL A 69 VAL A 67 PHE A 57 ASP A 31	None None None None ZN A1001 (-2.2A)	1.04A	5y9mA-2xb3A: undetectable	5y9mA-2xb3A: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YF9_X_NIOX401_1 (CASEIN KINASE II SUBUNIT ALPHA')	2xb3	PSBP PROTEIN (Thermosynechococ cus elongatus)	5 / 9	LEU A 157 VAL A 69 VAL A 67 PHE A 57 ASP A 31	None None None None ZN A1001 (-2.2A)	0.97A	5yf9X-2xb3A: undetectable	5yf9X-2xb3A: 17.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6J20_A_GBQA1201_1 (SUBSTANCE-P RECEPTOR,ENDOLYSIN)	2xb3	PSBP PROTEIN (Thermosynechococ cus elongatus)	4 / 7	ILE A 124 TRP A 166 GLU A 170 VAL A 177	None None ZN A1003 (-2.1A) None	1.19A	6j20A-2xb3A: undetectable	6j20A-2xb3A: 15.16

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1SG9_A_SAMA301_0","HEMK PROTEIN","2xb3","PSBP PROTEIN","Thermosynechococcus elongatus",5,"GLY A  90;ILE A  97;SER A  85;GLU A  82;ASN A  96","None","1.08A","1sg9A-2xb3A:undetectable","1sg9A-2xb3A:22.06"],["5Y9M_A_NIOA401_1","CASEIN KINASE II SUBUNIT ALPHA'","2xb3","PSBP PROTEIN","Thermosynechococcus elongatus",5,"LEU A 157;VAL A  69;VAL A  67;PHE A  57;ASP A  31","None;None;None;None; ZN A1001 (-2.2A)","1.04A","5y9mA-2xb3A:undetectable","5y9mA-2xb3A:17.86"],["5YF9_X_NIOX401_1","CASEIN KINASE II SUBUNIT ALPHA'","2xb3","PSBP PROTEIN","Thermosynechococcus elongatus",5,"LEU A 157;VAL A  69;VAL A  67;PHE A  57;ASP A  31","None;None;None;None; ZN A1001 (-2.2A)","0.97A","5yf9X-2xb3A:undetectable","5yf9X-2xb3A:17.86"],["6J20_A_GBQA1201_1","SUBSTANCE-P RECEPTOR,ENDOLYSIN","2xb3","PSBP PROTEIN","Thermosynechococcus elongatus",4,"ILE A 124;TRP A 166;GLU A 170;VAL A 177","None;None; ZN A1003 (-2.1A);None","1.19A","6j20A-2xb3A:undetectable","6j20A-2xb3A:15.16"]]