SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xc8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_C_CCSC47_0 (GLUTATHIONE S-TRANSFERASE)	2xc8	GENE 22 PRODUCT (Bacillus phage SPP1)	4 / 6	THR A 49 LEU A 48 LYS A 77 TYR A 58	None	1.34A	1gtiC-2xc8A: undetectable	1gtiC-2xc8A: 17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_D_W9TD507_1 (HEMOLYTIC LECTIN CEL-III)	2xc8	GENE 22 PRODUCT (Bacillus phage SPP1)	4 / 5	GLU A 92 GLY A 90 TYR A 61 ASP A 87	None	1.43A	3w9tD-2xc8A: undetectable	3w9tD-2xc8A: 17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FOR_A_FLPA711_1 (LACTOTRANSFERRIN)	2xc8	GENE 22 PRODUCT (Bacillus phage SPP1)	4 / 7	GLY A 107 VAL A 103 PRO A 105 ASN A 106	None	0.87A	4forA-2xc8A: undetectable	4forA-2xc8A: 16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I00_A_ZMRA509_2 (NEURAMINIDASE)	2xc8	GENE 22 PRODUCT (Bacillus phage SPP1)	4 / 5	LEU A 31 TRP A 73 ILE A 17 ASN A 6	None	1.42A	4i00A-2xc8A: undetectable	4i00A-2xc8A: 17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QC6_A_KANA201_1 (BIFUNCTIONAL AAC/APH)	2xc8	GENE 22 PRODUCT (Bacillus phage SPP1)	5 / 11	TYR A 85 GLY A 84 GLN A 89 ASP A 87 GLU A 57	None	1.49A	4qc6A-2xc8A: undetectable	4qc6A-2xc8A: 22.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QC6_B_KANB201_1 (BIFUNCTIONAL AAC/APH)	2xc8	GENE 22 PRODUCT (Bacillus phage SPP1)	5 / 12	TYR A 85 GLY A 84 GLN A 89 ASP A 87 GLU A 57	None	1.49A	4qc6B-2xc8A: undetectable	4qc6B-2xc8A: 22.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTI_C_CCSC47_0","GLUTATHIONE S-TRANSFERASE","2xc8","GENE 22 PRODUCT","Bacillus phage SPP1",4,"THR A  49;LEU A  48;LYS A  77;TYR A  58","None","1.34A","1gtiC-2xc8A:undetectable","1gtiC-2xc8A:17.39"],["3W9T_D_W9TD507_1","HEMOLYTIC LECTIN CEL-III","2xc8","GENE 22 PRODUCT","Bacillus phage SPP1",4,"GLU A  92;GLY A  90;TYR A  61;ASP A  87","None","1.43A","3w9tD-2xc8A:undetectable","3w9tD-2xc8A:17.55"],["4FOR_A_FLPA711_1","LACTOTRANSFERRIN","2xc8","GENE 22 PRODUCT","Bacillus phage SPP1",4,"GLY A 107;VAL A 103;PRO A 105;ASN A 106","None","0.87A","4forA-2xc8A:undetectable","4forA-2xc8A:16.13"],["4I00_A_ZMRA509_2","NEURAMINIDASE","2xc8","GENE 22 PRODUCT","Bacillus phage SPP1",4,"LEU A  31;TRP A  73;ILE A  17;ASN A   6","None","1.42A","4i00A-2xc8A:undetectable","4i00A-2xc8A:17.65"],["4QC6_A_KANA201_1","BIFUNCTIONAL AAC\/APH","2xc8","GENE 22 PRODUCT","Bacillus phage SPP1",5,"TYR A  85;GLY A  84;GLN A  89;ASP A  87;GLU A  57","None","1.49A","4qc6A-2xc8A:undetectable","4qc6A-2xc8A:22.02"],["4QC6_B_KANB201_1","BIFUNCTIONAL AAC\/APH","2xc8","GENE 22 PRODUCT","Bacillus phage SPP1",5,"TYR A  85;GLY A  84;GLN A  89;ASP A  87;GLU A  57","None","1.49A","4qc6B-2xc8A:undetectable","4qc6B-2xc8A:22.02"]]