SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xcz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HPV_B_478B200_2 (HIV-1 PROTEASE)	2xcz	POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN (Prochlorococcus marinus)	5 / 9	ALA A 91 ASP A 92 GLY A 88 VAL A 59 ILE A 94	None	1.16A	1hpvB-2xczA: undetectable	1hpvB-2xczA: 26.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FT9_A_CHDA130_0 (FATTY ACID-BINDING PROTEIN 2, LIVER)	2xcz	POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN (Prochlorococcus marinus)	5 / 12	ILE A 94 ILE A 89 CYH A 57 VAL A 59 LEU A 18	None	1.08A	2ft9A-2xczA: undetectable	2ft9A-2xczA: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZM8_A_ACAA511_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	2xcz	POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN (Prochlorococcus marinus)	4 / 8	ALA A 7 ILE A 5 ILE A 89 HIS A 82	None	1.02A	2zm8A-2xczA: undetectable	2zm8A-2xczA: 17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZMA_A_ACAA501_1 (6-AMINOHEXANOATE-DIM ER HYDROLASE)	2xcz	POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN (Prochlorococcus marinus)	4 / 8	ALA A 7 ILE A 5 ILE A 89 HIS A 82	None	1.03A	2zmaA-2xczA: undetectable	2zmaA-2xczA: 18.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HPV_B_478B200_2","HIV-1 PROTEASE","2xcz","POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN","Prochlorococcus marinus",5,"ALA A  91;ASP A  92;GLY A  88;VAL A  59;ILE A  94","None","1.16A","1hpvB-2xczA:undetectable","1hpvB-2xczA:26.67"],["2FT9_A_CHDA130_0","FATTY ACID-BINDING PROTEIN 2, LIVER","2xcz","POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN","Prochlorococcus marinus",5,"ILE A  94;ILE A  89;CYH A  57;VAL A  59;LEU A  18","None","1.08A","2ft9A-2xczA:undetectable","2ft9A-2xczA:20.59"],["2ZM8_A_ACAA511_1","6-AMINOHEXANOATE-DIMER HYDROLASE","2xcz","POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN","Prochlorococcus marinus",4,"ALA A   7;ILE A   5;ILE A  89;HIS A  82","None","1.02A","2zm8A-2xczA:undetectable","2zm8A-2xczA:17.15"],["2ZMA_A_ACAA501_1","6-AMINOHEXANOATE-DIMER HYDROLASE","2xcz","POSSIBLE ATLS1-LIKE LIGHT-INDUCIBLE PROTEIN","Prochlorococcus marinus",4,"ALA A   7;ILE A   5;ILE A  89;HIS A  82","None","1.03A","2zmaA-2xczA:undetectable","2zmaA-2xczA:18.02"]]