SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xdd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		3 / 3 GLU A  16
TYR A  13
PHE A  17
 None
 0.97A 1eqbB-2xddA:
undetectable		 1eqbB-2xddA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_FFOB2293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		3 / 3 GLU A  16
TYR A  13
PHE A  17
 None
 0.96A 1eqbA-2xddA:
undetectable		 1eqbA-2xddA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		3 / 3 GLU A  16
TYR A  13
PHE A  17
 None
 0.97A 1eqbD-2xddA:
undetectable		 1eqbD-2xddA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_FFOD4293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		3 / 3 GLU A  16
TYR A  13
PHE A  17
 None
 0.97A 1eqbC-2xddA:
undetectable		 1eqbC-2xddA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		3 / 3 HIS A  45
ILE A  92
LEU A  14
 None
 0.66A 2kceA-2xddA:
undetectable		 2kceA-2xddA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		4 / 5 GLU A  41
GLY A  44
TYR A  47
GLU A 154
 None
 1.37A 3w9tA-2xddA:
undetectable		 3w9tA-2xddA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		4 / 5 GLU A  41
GLY A  44
TYR A  47
GLU A 154
 None
 1.37A 3w9tC-2xddA:
undetectable		 3w9tC-2xddA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		4 / 5 GLU A  41
GLY A  44
TYR A  47
GLU A 154
 None
 1.36A 3w9tD-2xddA:
undetectable		 3w9tD-2xddA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		4 / 5 GLU A  41
GLY A  44
TYR A  47
GLU A 154
 None
 1.36A 3w9tG-2xddA:
undetectable		 3w9tG-2xddA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JHD_E_EDTE301_0
(BETA-2-MICROGLOBULIN
TCRBETA CHAIN)		 2xdd TOXN
(Pectobacterium
atrosepticum) 		4 / 8 TYR A  29
SER A  24
PRO A  50
ILE A   6
 None
 1.01A 5jhdE-2xddA:
undetectable
5jhdG-2xddA:
undetectable		 5jhdE-2xddA:
24.00
5jhdG-2xddA:
17.54