SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xdq'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CD2_A_FOLA307_0 (DIHYDROFOLATE REDUCTASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 12	PHE B  23 THR B 229 PHE B 145 LEU B 209 ILE B 200	None	1.09A	1cd2A-2xdqB: undetectable	1cd2A-2xdqB: 17.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1CMA_B_SAMB105_0 (PROTEIN (MET REPRESSOR))	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 11	GLU A 301 LEU A 308 ALA A 432 PHE A 429 GLY A 430	None	1.38A	1cmaA-2xdqA: undetectable 1cmaB-2xdqA: undetectable	1cmaA-2xdqA: 16.62 1cmaB-2xdqA: 16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FXH_B_PACB1001_0 (PENICILLIN ACYLASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 7	PHE B  39 SER B  22 ALA B  20 ILE B  19	None	1.06A	1fxhA-2xdqB: undetectable 1fxhB-2xdqB: undetectable	1fxhA-2xdqB: 17.08 1fxhB-2xdqB: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GM7_B_PNNB1577_0 (PENICILLIN G ACYLASE ALPHA SUBUNIT PENICILLIN G ACYLASE BETA SUBUNIT)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 8	PHE B  39 SER B  22 ALA B  20 ILE B  19	None	1.02A	1gm7A-2xdqB: undetectable 1gm7B-2xdqB: undetectable	1gm7A-2xdqB: 17.08 1gm7B-2xdqB: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GRM_A_DVAA6_0 (GRAMICIDIN A)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	ALA A 246 VAL A 200 TRP A 227	None	0.89A	1grmA-2xdqA: undetectable	1grmA-2xdqA: 3.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GRM_B_DVAB6_0 (GRAMICIDIN A)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	ALA A 246 VAL A 200 TRP A 227	None	0.88A	1grmB-2xdqA: undetectable	1grmB-2xdqA: 3.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GX8_A_RTLA1163_0 (BETA-LACTOGLOBULIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 9	LEU B 185 LEU B 192 ILE B 256 VAL B 242 PHE B 217	None	0.86A	1gx8A-2xdqB: undetectable	1gx8A-2xdqB: 18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HRK_A_CHDA1503_0 (FERROCHELATASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	LEU A 374 PRO A 375 LEU A   9	None	0.51A	1hrkA-2xdqA: 2.6	1hrkA-2xdqA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JO4_A_DVAA6_0 (GRAMICIDIN C)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	ALA A 246 VAL A 200 TRP A 227	None	0.92A	1jo4A-2xdqA: undetectable	1jo4A-2xdqA: 2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JO4_B_DVAB6_0 (GRAMICIDIN C)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	ALA A 246 VAL A 200 TRP A 227	None	0.92A	1jo4B-2xdqA: undetectable	1jo4B-2xdqA: 2.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1LIN_A_TFPA154_1 (CALMODULIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 7	GLU A  84 LEU A  88 LEU A  70 MET A 114	None	0.91A	1linA-2xdqA: undetectable	1linA-2xdqA: 13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NBH_B_SAMB1293_0 (GLYCINE N-METHYLTRANSFERASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	6 / 12	TYR B   8 GLY B 375 VAL B 304 ALA B 395 GLY B 331 LEU B 132	None	1.50A	1nbhB-2xdqB: 4.1	1nbhB-2xdqB: 19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRM_A_DVAA6_0 (GRAMICIDIN A)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	ALA A 246 VAL A 200 TRP A 227	None	0.93A	1nrmA-2xdqA: undetectable	1nrmA-2xdqA: 3.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NRM_B_DVAB6_0 (GRAMICIDIN A)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	ALA A 246 VAL A 200 TRP A 227	None	0.93A	1nrmB-2xdqA: undetectable	1nrmB-2xdqA: 3.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PNL_B_PACB559_0 (PENICILLIN AMIDOHYDROLASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 8	PHE B  39 SER B  22 ALA B  20 ILE B  19	None	1.02A	1pnlA-2xdqB: undetectable 1pnlB-2xdqB: undetectable	1pnlA-2xdqB: 17.08 1pnlB-2xdqB: 21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SBR_B_VIBB504_1 (YKOF)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 6	PRO B 201 PHE B 217 LEU B 219 ILE B 168	None	1.24A	1sbrA-2xdqB: undetectable 1sbrB-2xdqB: undetectable	1sbrA-2xdqB: 19.68 1sbrB-2xdqB: 19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T87_B_CAMB2422_0 (CYTOCHROME P450-CAM)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 7	PHE A 421 LEU A 436 VAL A 320 ILE A 399	None	0.97A	1t87B-2xdqA: undetectable	1t87B-2xdqA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_A_CTXA11_1 (CES1 PROTEIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 8	PRO B 246 MET B 247 LEU B 188 PRO B 408	None	0.92A	1ya4A-2xdqB: undetectable	1ya4A-2xdqB: 22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZGY_A_BRLA503_2 (PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 5	ILE B 422 ILE B 365 ILE B 393 MET B 315	None	0.93A	1zgyA-2xdqB: undetectable	1zgyA-2xdqB: 21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2A1H_A_GBNA502_1 (BRANCHED CHAIN AMINOTRANSFERASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 8	GLY B 226 THR B 229 ALA B 230 VAL B 166	None	0.87A	2a1hA-2xdqB: undetectable 2a1hB-2xdqB: undetectable	2a1hA-2xdqB: 21.02 2a1hB-2xdqB: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BR4_F_SAMF301_1 (CEPHALOSPORIN HYDROXYLASE CMCI)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus; Thermosynechococ cus elongatus)	3 / 3	LYS B  72 ASP B  36 CYH A 107	None SF4  A 602 (-2.8A) SF4  A 602 (-2.3A)	1.32A	2br4F-2xdqB: 3.4	2br4F-2xdqB: 18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EZ7_A_DHIA301_0 (CARBONIC ANHYDRASE 2)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 6	ASN B 167 GLN B 239 THR B 161 PRO B 164	None	1.23A	2ez7A-2xdqB: undetectable	2ez7A-2xdqB: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO5_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	LEU A 374 PRO A 375 LEU A   9	None	0.62A	2po5B-2xdqA: 5.8	2po5B-2xdqA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PO7_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	LEU A 374 PRO A 375 LEU A   9	None	0.57A	2po7B-2xdqA: 2.7	2po7B-2xdqA: 23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QAK_A_1UNA1001_4 (PROTEASE RETROPEPSIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	3 / 3	ASP B 208 THR B 161 PRO B 162	None	0.72A	2qakB-2xdqB: undetectable	2qakB-2xdqB: 14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QBM_A_CAMA517_0 (CYTOCHROME P450-CAM)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 8	PHE A 421 THR A 440 VAL A 320 ILE A 399	None	0.95A	2qbmA-2xdqA: undetectable	2qbmA-2xdqA: 21.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QD5_B_CHDB1104_0 (FERROCHELATASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	LEU A 374 PRO A 375 LEU A   9	None	0.36A	2qd5B-2xdqA: 2.7	2qd5B-2xdqA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_PCFA1179_1 (WNT INHIBITORY FACTOR 1)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 5	ILE A 104 PRO A  23 VAL A 210 PHE A 251	None	1.22A	2ygnA-2xdqA: undetectable	2ygnA-2xdqA: 16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YOE_C_FL7C1318_1 (CYS-LOOP LIGAND-GATED ION CHANNEL)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 8	GLY A 105 ILE B  99 VAL B  60 THR A  44	None	0.92A	2yoeB-2xdqA: undetectable 2yoeC-2xdqA: undetectable	2yoeB-2xdqA: 21.08 2yoeC-2xdqA: 21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CWK_A_REAA300_1 (CELLULAR RETINOIC ACID-BINDING PROTEIN 2)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 12	PHE B 374 LEU B 319 ALA B 303 ALA B 372 PRO B 389	None	1.26A	3cwkA-2xdqB: undetectable	3cwkA-2xdqB: 14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DDY_A_RBFA187_1 (LUMAZINE PROTEIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 12	ILE B 225 ASP B 136 ALA B 135 THR B  16 ILE B  14	None	1.18A	3ddyA-2xdqB: undetectable	3ddyA-2xdqB: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EM0_B_CHDB150_0 (ILEAL BILE ACID-BINDING PROTEIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 12	ILE B  89 ASN B  40 THR B  56 LEU B 174 THR B 173	None	1.11A	3em0B-2xdqB: undetectable	3em0B-2xdqB: 14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FPJ_A_SAMA301_1 (PUTATIVE UNCHARACTERIZED PROTEIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 6	TYR A  18 GLY A 138 THR A  20 GLU A 110	None SF4  A 602 (-3.6A) None None	0.90A	3fpjA-2xdqA: undetectable	3fpjA-2xdqA: 21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HCR_A_CHDA4_0 (FERROCHELATASE, MITOCHONDRIAL)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	LEU A 374 PRO A 375 LEU A   9	None	0.40A	3hcrA-2xdqA: 2.5	3hcrA-2xdqA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IA4_C_MTXC164_2 (DIHYDROFOLATE REDUCTASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 4	ILE B  99 ARG A 135 ILE A 112 THR B  94	None	1.25A	3ia4C-2xdqB: undetectable	3ia4C-2xdqB: 15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IB1_A_IMNA701_1 (LACTOTRANSFERRIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 4	PRO B 246 THR B 245 GLY B 226 THR B 229	None	1.08A	3ib1A-2xdqB: undetectable	3ib1A-2xdqB: 19.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LSL_G_PZIG801_0 (GLUTAMATE RECEPTOR 2)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	PRO A 250 SER A 331 ASN A 326	None	0.90A	3lslG-2xdqA: undetectable	3lslG-2xdqA: 18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MG0_H_BO2H1400_1 (PROTEASOME COMPONENT PUP1 PROTEASOME COMPONENT PUP3)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 11	THR B 158 GLN B 214 GLY B 154 THR B 155 ALA B 150	None	1.03A	3mg0H-2xdqB: undetectable 3mg0I-2xdqB: undetectable	3mg0H-2xdqB: 18.46 3mg0I-2xdqB: 17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N58_C_ADNC500_2 (ADENOSYLHOMOCYSTEINA SE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 5	LEU A 362 GLN A 285 THR A 281 GLU A 359	None	1.37A	3n58C-2xdqA: undetectable	3n58C-2xdqA: 24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NXU_B_RITB600_1 (CYTOCHROME P450 3A4)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 12	PHE A 251 LEU A 205 THR A 149 ILE A 426 ALA A 424	None	1.12A	3nxuB-2xdqA: undetectable	3nxuB-2xdqA: 21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3PGY_A_GLYA510_0 (SERINE HYDROXYMETHYLTRANSFE RASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 6	ILE B  14 GLU B 131 ALA B 134 ASN B 130	None	1.14A	3pgyA-2xdqB: 2.8 3pgyB-2xdqB: 3.0	3pgyA-2xdqB: 21.92 3pgyB-2xdqB: 21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TGV_B_BEZB1_0 (HEME-BINDING PROTEIN HUTZ)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 6	GLN A 266 TYR A 244 PHE A 290 PRO A 197	None	0.99A	3tgvB-2xdqA: undetectable	3tgvB-2xdqA: 15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TGV_D_BEZD1_0 (HEME-BINDING PROTEIN HUTZ)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 6	GLN A 266 TYR A 244 PHE A 290 PRO A 197	None	0.99A	3tgvD-2xdqA: undetectable	3tgvD-2xdqA: 15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W1W_B_CHDB503_0 (FERROCHELATASE, MITOCHONDRIAL)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	LEU A 374 PRO A 375 LEU A   9	None	0.45A	3w1wB-2xdqA: 2.6	3w1wB-2xdqA: 22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AWU_A_4CHA502_0 (OXIDOREDUCTASE, FMN-BINDING)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 7	THR B 332 ASN B 130 TYR B 336 LEU B 132	None	1.39A	4awuA-2xdqB: undetectable	4awuA-2xdqB: 23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4EIL_E_FOLE703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 11	ALA A 134 MET A  67 LEU A  51 VAL A  27 THR A 149	None	1.48A	4eilE-2xdqA: undetectable	4eilE-2xdqA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4J7X_B_SASB804_2 (SEPIAPTERIN REDUCTASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	LEU A  51 MET A  55 ASP A 148	None	0.73A	4j7xB-2xdqA: 2.6	4j7xB-2xdqA: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KJJ_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 12	ILE B  19 ALA B 203 PHE B  23 LEU B 209 ILE B 142	None	1.04A	4kjjA-2xdqB: undetectable	4kjjA-2xdqB: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KLA_A_CHDA502_0 (FERROCHELATASE, MITOCHONDRIAL)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 8	LEU B 185 LEU B 188 LEU B 192 VAL B 242	None	0.85A	4klaA-2xdqB: 3.9	4klaA-2xdqB: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KOU_A_C04A207_1 (UNCHARACTERIZED PROTEIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	GLY A 138 GLU A 110 THR A 106	SF4  A 602 (-3.6A) None SF4  A 602 ( 3.6A)	0.57A	4kouA-2xdqA: undetectable	4kouA-2xdqA: 17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_B_FOLB703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 12	ALA A 134 MET A  67 LEU A  51 VAL A  27 THR A 149	None	1.47A	4kyaB-2xdqA: undetectable	4kyaB-2xdqA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_C_FOLC703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 10	ALA A 134 MET A  67 LEU A  51 VAL A  27 THR A 149	None	1.47A	4kyaC-2xdqA: undetectable	4kyaC-2xdqA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_D_FOLD703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 12	ALA A 134 MET A  67 LEU A  51 VAL A  27 THR A 149	None	1.45A	4kyaD-2xdqA: undetectable	4kyaD-2xdqA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KYA_F_FOLF703_0 (BIFUNCTIONAL DIHYDROFOLATE REDUCTASE-THYMIDYLAT E SYNTHASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 12	ALA A 134 MET A  67 LEU A  51 VAL A  27 THR A 149	None	1.43A	4kyaF-2xdqA: undetectable	4kyaF-2xdqA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LG1_C_SAMC301_0 (PROTEIN-LYSINE METHYLTRANSFERASE METTL21D)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 12	ALA B 253 GLY B 411 GLY B 248 LEU B 418 TYR B 222	None	1.11A	4lg1C-2xdqB: undetectable	4lg1C-2xdqB: 18.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MA7_A_P2ZA301_1 (MAJOR PRION PROTEIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 8	VAL A 209 LEU A 213 ILE A 283 THR A 304	None	0.96A	4ma7A-2xdqA: undetectable	4ma7A-2xdqA: 13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NJH_A_SAMA302_0 (7-CARBOXY-7-DEAZAGUA NINE SYNTHASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 12	GLU B 322 THR B 280 THR B 252 GLU B 184 VAL B 419	None	1.49A	4njhA-2xdqB: 0.1	4njhA-2xdqB: 19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4P7N_A_GCSA702_1 (POLY-BETA-1,6-N-ACET YL-D-GLUCOSAMINE N-DEACETYLASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	3 / 3	ASP B 337 TYR B 336 TRP B 340	None	1.26A	4p7nA-2xdqB: undetectable	4p7nA-2xdqB: 20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVV_H_BO2H301_1 (PROTEASOME SUBUNIT BETA TYPE-2)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 11	THR B 158 GLN B 214 GLY B 154 THR B 155 ALA B 150	None	0.88A	4qvvH-2xdqB: undetectable	4qvvH-2xdqB: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVV_V_BO2V301_1 (PROTEASOME SUBUNIT BETA TYPE-2)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 11	THR B 158 GLN B 214 GLY B 154 THR B 155 ALA B 150	None	0.87A	4qvvV-2xdqB: undetectable	4qvvV-2xdqB: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QVY_H_BO2H301_1 (PROTEASOME SUBUNIT BETA TYPE-2)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 11	THR B 158 GLN B 214 GLY B 154 THR B 155 ALA B 150	None	0.93A	4qvyH-2xdqB: undetectable	4qvyH-2xdqB: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XMF_A_HSMA202_1 (NITROPHORIN-7)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	ASP B  36 LEU A 139 GLY A 138	SF4  A 602 (-2.8A) None SF4  A 602 (-3.6A)	0.47A	4xmfA-2xdqB: undetectable	4xmfA-2xdqB: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BMV_C_VLBC507_2 (TUBULIN ALPHA-1B CHAIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 7	PRO B 213 ASN B 167 ILE B 200 VAL B 143 ILE B 147	None	1.47A	5bmvC-2xdqB: 2.3	5bmvC-2xdqB: 23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BXN_V_BO2V301_1 (PROTEASOME SUBUNIT BETA TYPE-2 PROTEASOME SUBUNIT BETA TYPE-3)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 11	THR B 158 GLN B 214 GLY B 154 THR B 155 ALA B 150	None	1.10A	5bxnV-2xdqB: undetectable 5bxnW-2xdqB: undetectable	5bxnV-2xdqB: 18.18 5bxnW-2xdqB: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5D0X_V_BO2V301_1 (PROTEASOME SUBUNIT BETA TYPE-2)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 11	THR B 158 GLN B 214 GLY B 154 THR B 155 ALA B 150	None	0.89A	5d0xV-2xdqB: undetectable	5d0xV-2xdqB: 18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G08_A_Z80A1187_1 (FREQUENIN 2)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 6	ILE A 348 PHE A  11 PHE A 272 THR A 269	None	1.33A	5g08A-2xdqA: undetectable	5g08A-2xdqA: 17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5JLC_A_1YNA602_2 (LANOSTEROL 14-ALPHA DEMETHYLASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 5	TYR A 355 THR A 257 GLY A 221 LEU A 201	None	0.88A	5jlcA-2xdqA: undetectable	5jlcA-2xdqA: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KF8_A_GCSA404_1 (PREDICTED ACETYLTRANSFERASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 8	TRP A 305 GLU A 301 GLY A 275 PRO A 276	None	1.07A	5kf8A-2xdqA: 2.0	5kf8A-2xdqA: 23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KR2_A_ROCA101_1 (PROTEASE PR5-SQV)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 9	ASN B 178 GLY B 226 ILE B 169 THR B 245 PRO B 246	None	1.21A	5kr2A-2xdqB: undetectable	5kr2A-2xdqB: 13.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5N5D_B_SAMB303_1 (METHYLTRANSFERASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus; Thermosynechococ cus elongatus)	4 / 7	PHE A  50 ARG B  43 ASP B  36 ASN B  40	None None SF4  A 602 (-2.8A) None	1.02A	5n5dB-2xdqA: undetectable	5n5dB-2xdqA: 20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OH1_C_9UQC202_0 (CEREBLON ISOFORM 4)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 8	ASN A 249 PRO A 250 GLU A 359 TRP A 282	None	1.46A	5oh1C-2xdqA: undetectable	5oh1C-2xdqA: 16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UMW_B_RBFB201_1 (GLYOXALASE/BLEOMYCIN RESISANCE PROTEIN/DIOXYGENASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 7	ARG A 444 TYR A 311 GLU A 437 LEU A 397	None	1.15A	5umwB-2xdqA: undetectable 5umwE-2xdqA: undetectable	5umwB-2xdqA: 10.85 5umwE-2xdqA: 10.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VLM_E_CVIE301_0 (REGULATORY PROTEIN TETR)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 12	ALA B 312 GLU B 322 LEU B 418 ILE B 422 VAL B 327	None	0.93A	5vlmE-2xdqB: undetectable	5vlmE-2xdqB: 17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VM8_B_SAMB301_0 (RIBOSOMAL RNA SMALL SUBUNIT METHYLTRANSFERASE E)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	5 / 10	VAL B 249 GLY B 248 ILE B 422 THR B 415 ALA B 286	None	0.99A	5vm8B-2xdqB: undetectable	5vm8B-2xdqB: 20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_A_SAMA902_1 (MRNA CAPPING ENZYME P5)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	3 / 3	TYR A 350 ASP A 148 ASP A 352	None	0.62A	5x6yA-2xdqA: 3.0	5x6yA-2xdqA: 19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y9M_A_NIOA401_1 (CASEIN KINASE II SUBUNIT ALPHA')	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 8	LEU A 205 VAL A 209 ILE A 426 ASP A 434	None	0.70A	5y9mA-2xdqA: undetectable	5y9mA-2xdqA: 10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y9M_X_NIOX401_1 (CASEIN KINASE II SUBUNIT ALPHA')	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 8	LEU A 205 VAL A 209 ILE A 426 ASP A 434	None	0.73A	5y9mX-2xdqA: undetectable	5y9mX-2xdqA: 10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6APH_A_ADNA501_2 (ADENOSYLHOMOCYSTEINA SE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 5	THR B 252 THR B 310 HIS B 311 LEU B 418	None	1.40A	6aphA-2xdqB: 6.3	6aphA-2xdqB: 21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AWO_A_SREA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 9	ALA A 134 ILE A 104 GLY A 138 SER A  25 GLY A 146	None None SF4  A 602 (-3.6A) None None	1.32A	6awoA-2xdqA: undetectable	6awoA-2xdqA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AWQ_A_SREA701_1 (SODIUM-DEPENDENT SEROTONIN TRANSPORTER)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 9	ALA A 134 ILE A 104 GLY A 138 SER A  25 GLY A 146	None None SF4  A 602 (-3.6A) None None	1.33A	6awqA-2xdqA: undetectable	6awqA-2xdqA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BXL_B_SAMB401_0 (2-(3-AMINO-3-CARBOXY PROPYL)HISTIDINE SYNTHASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 12	LEU A 205 GLY A 203 SER A  37 VAL A 102 VAL A 150	None	1.38A	6bxlB-2xdqA: 2.4	6bxlB-2xdqA: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BXL_B_SAMB401_0 (2-(3-AMINO-3-CARBOXY PROPYL)HISTIDINE SYNTHASE)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 12	LEU A 205 GLY A 203 SER A  37 VAL A 150 ASP A 148	None	1.40A	6bxlB-2xdqA: 2.4	6bxlB-2xdqA: 21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DJZ_A_GMJA301_0 (SIGMA NON-OPIOID INTRACELLULAR RECEPTOR 1)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	5 / 12	LEU A  88 ILE A 101 VAL A  27 LEU A 119 TYR A  82	None	1.21A	6djzA-2xdqA: undetectable	6djzA-2xdqA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GBN_B_ADNB501_2 (-)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus)	4 / 5	THR B 252 THR B 310 HIS B 311 LEU B 418	None	1.40A	6gbnB-2xdqB: 4.9	6gbnB-2xdqB: 23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GH9_A_MIXA1003_0 (UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 15)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus; Thermosynechococ cus elongatus)	4 / 5	TYR A  18 GLY A 324 HIS A  19 ASP B  37	None	1.24A	6gh9A-2xdqA: undetectable	6gh9A-2xdqA: 12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6IE8_A_CHDA201_0 (REGULATORY PROTEIN)	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT B (Thermosynechococ cus elongatus; Thermosynechococ cus elongatus)	5 / 12	THR A 108 ILE A 112 LEU A  70 MET B   1 LEU A 119	None	1.07A	6ie8A-2xdqA: undetectable	6ie8A-2xdqA: 17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6N7F_A_RBFA502_0 (PUTATIVE GLUTATHIONE REDUCTASE (GR))	2xdq	LIGHT-INDEPENDENT PROTOCHLOROPHYLLIDE REDUCTASE SUBUNIT N (Thermosynechococ cus elongatus)	4 / 7	GLY A 347 HIS A  19 ASN A 383 GLY A  16	None	0.78A	6n7fA-2xdqA: undetectable	6n7fA-2xdqA: 12.96