SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xdv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MOG_A_RBFA200_1
(DODECIN)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		3 / 3 PHE A 158
TRP A  59
GLU A  60
 None
 1.10A 1mogA-2xdvA:
0.5		 1mogA-2xdvA:
9.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2001_1
(SERUM ALBUMIN)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		5 / 11 LEU A  33
ILE A 150
ARG A  68
VAL A 254
LEU A  80
 None
 1.16A 2bxeA-2xdvA:
undetectable		 2bxeA-2xdvA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		5 / 12 LEU A 198
PHE A 234
LEU A 226
ILE A 187
ALA A 242
 None
None
None
None
OGA  A 601 ( 4.2A)
 1.18A 2bxpA-2xdvA:
undetectable		 2bxpA-2xdvA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FJ1_A_CTCA222_0
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		5 / 12 SER A 257
PRO A 140
THR A 255
VAL A 254
ILE A 150
 None
None
OGA  A 601 (-3.0A)
None
None
 1.42A 2fj1A-2xdvA:
undetectable		 2fj1A-2xdvA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YPM_A_BO2A801_1
(LON PROTEASE)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		5 / 12 ALA A  72
THR A  75
PRO A  30
SER A  31
ALA A  32
 None
 1.21A 4ypmA-2xdvA:
undetectable		 4ypmA-2xdvA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_E_ACTE403_0
(PROTON-GATED ION
CHANNEL)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		3 / 3 ARG A 216
TYR A 180
GLU A 212
 None
 0.67A 4zzbE-2xdvA:
undetectable		 4zzbE-2xdvA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_H_ACTH614_0
(NADH DEHYDROGENASE,
PUTATIVE)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		4 / 6 ILE A 462
VAL A 438
VAL A 453
SER A 362
 None
 0.95A 5jwaH-2xdvA:
undetectable		 5jwaH-2xdvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		3 / 3 THR A 258
SER A 160
ASP A 266
 None
 0.76A 5kvaA-2xdvA:
undetectable		 5kvaA-2xdvA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		3 / 3 THR A 258
SER A 160
ASP A 266
 None
 0.76A 5kvaB-2xdvA:
undetectable		 5kvaB-2xdvA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LRB_A_ACRA1003_1
(ALPHA-1,4 GLUCAN
PHOSPHORYLASE)		 2xdv MYC-INDUCED NUCLEAR
ANTIGEN
(Homo
sapiens) 		4 / 6 GLU A 146
THR A  75
TYR A  76
PHE A  35
 None
 1.35A 5lrbA-2xdvA:
undetectable		 5lrbA-2xdvA:
19.28