SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xdy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA152_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 2xdy POST-TRANSCRIPTIONAL
GENE SILENCING
PROTEIN QDE-2
(Neurospora
crassa) 		3 / 3 VAL A 635
LYS A 638
HIS A 580
 None
SO4  A1642 ( 2.9A)
None
 0.81A 3elzA-2xdyA:
undetectable		 3elzA-2xdyA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2xdy POST-TRANSCRIPTIONAL
GENE SILENCING
PROTEIN QDE-2
(Neurospora
crassa) 		4 / 6 VAL A 598
PRO A 563
ALA A 602
THR A 605
 None
None
SO4  A1642 (-3.5A)
None
 1.03A 6cduB-2xdyA:
undetectable
6cduC-2xdyA:
undetectable		 6cduB-2xdyA:
19.20
6cduC-2xdyA:
19.20