SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xeh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEO_A_LNRA200_1 (D7R4 PROTEIN)	2xeh	NI3C MUT6 (synthetic construct)	5 / 12	GLU A 57 ARG A 56 HIS A 59 ILE A 62 ASP A 44	None SO4 A1172 ( 2.8A) None None None	1.14A	2qeoA-2xehA: undetectable	2qeoA-2xehA: 23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QEO_B_LNRB200_1 (D7R4 PROTEIN)	2xeh	NI3C MUT6 (synthetic construct)	5 / 10	GLU A 57 ARG A 56 HIS A 59 ILE A 62 ASP A 44	None SO4 A1172 ( 2.8A) None None None	1.13A	2qeoB-2xehA: undetectable	2qeoB-2xehA: 23.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DH0_A_SAMA220_1 (SAM DEPENDENT METHYLTRANSFERASE)	2xeh	NI3C MUT6 (synthetic construct)	4 / 8	ARG A 89 TYR A 81 GLU A 20 GLU A 57	SO4 A1170 ( 3.0A) SO4 A1171 (-4.4A) None None	1.31A	3dh0A-2xehA: undetectable	3dh0A-2xehA: 22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MN4_C_AM2C301_0 (AMINOGLYCOSIDE N(3)-ACETYLTRANSFERA SE, AAC(3)-IVA)	2xeh	NI3C MUT6 (synthetic construct)	4 / 8	ASP A 143 ARG A 122 HIS A 118 GLU A 156	None SO4 A1171 (-3.0A) None None	1.14A	6mn4C-2xehA: undetectable	6mn4C-2xehA: 20.68

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2QEO_A_LNRA200_1","D7R4 PROTEIN","2xeh","NI3C MUT6","synthetic construct",5,"GLU A  57;ARG A  56;HIS A  59;ILE A  62;ASP A  44","None;SO4 A1172 ( 2.8A);None;None;None","1.14A","2qeoA-2xehA:undetectable","2qeoA-2xehA:23.81"],["2QEO_B_LNRB200_1","D7R4 PROTEIN","2xeh","NI3C MUT6","synthetic construct",5,"GLU A  57;ARG A  56;HIS A  59;ILE A  62;ASP A  44","None;SO4 A1172 ( 2.8A);None;None;None","1.13A","2qeoB-2xehA:undetectable","2qeoB-2xehA:23.81"],["3DH0_A_SAMA220_1","SAM DEPENDENT METHYLTRANSFERASE","2xeh","NI3C MUT6","synthetic construct",4,"ARG A  89;TYR A  81;GLU A  20;GLU A  57","SO4 A1170 ( 3.0A);SO4 A1171 (-4.4A);None;None","1.31A","3dh0A-2xehA:undetectable","3dh0A-2xehA:22.01"],["6MN4_C_AM2C301_0","AMINOGLYCOSIDE N(3)-ACETYLTRANSFERASE, AAC(3)-IVA","2xeh","NI3C MUT6","synthetic construct",4,"ASP A 143;ARG A 122;HIS A 118;GLU A 156","None;SO4 A1171 (-3.0A);None;None","1.14A","6mn4C-2xehA:undetectable","6mn4C-2xehA:20.68"]]