SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xf2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DX6_A_GNTA602_1
(ACETYLCHOLINESTERASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 ASP A 461
TRP A 240
GLY A 197
GLY A 195
PHE A 521
 None
 1.01A 1dx6A-2xf2A:
undetectable		 1dx6A-2xf2A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 LEU A 490
ASP A 688
MET A 193
LEU A 189
 None
 1.22A 1errB-2xf2A:
undetectable		 1errB-2xf2A:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 GLY A 107
ASP A 117
GLY A 120
THR A  68
 None
None
HDD  A 690 (-3.5A)
None
 0.83A 1hxbB-2xf2A:
undetectable		 1hxbB-2xf2A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 8 GLY A 642
GLY A 649
PHE A 598
LEU A 626
SER A 648
 None
 1.40A 1jhqA-2xf2A:
3.6		 1jhqA-2xf2A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 8 GLY A 642
GLY A 649
PHE A 598
LEU A 626
SER A 648
 None
 1.41A 1jhvA-2xf2A:
2.9		 1jhvA-2xf2A:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 ILE A 459
PHE A 458
ALA A 194
PHE A 447
LEU A 682
 None
 1.15A 1og5B-2xf2A:
undetectable		 1og5B-2xf2A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA471_1
(CYTOCHROME P450 51)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 8 PHE A 253
ALA A 236
HIS A 204
LEU A 531
 None
 0.99A 1x8vA-2xf2A:
undetectable		 1x8vA-2xf2A:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLX_B_CIOB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 HIS A 228
MET A 277
ILE A 295
GLN A 443
PHE A 287
 None
 1.43A 1xlxB-2xf2A:
undetectable		 1xlxB-2xf2A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B82_A_ADNA1001_1
(CLASS B ACID
PHOSPHATASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 10 PHE A  74
GLU A 269
TRP A 229
GLY A 273
TYR A  77
 None
 1.29A 2b82A-2xf2A:
3.3		 2b82A-2xf2A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B82_B_ADNB1002_1
(CLASS B ACID
PHOSPHATASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 9 PHE A  74
GLU A 269
TRP A 229
GLY A 273
TYR A  77
 None
 1.29A 2b82B-2xf2A:
3.3		 2b82B-2xf2A:
16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CDQ_A_SAMA1500_0
(ASPARTOKINASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 8 ILE A 486
SER A 487
SER A 450
LEU A 190
 None
 0.75A 2cdqA-2xf2A:
undetectable		 2cdqA-2xf2A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GEH_A_NHYA300_1
(CARBONIC ANHYDRASE 2)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 8 VAL A 274
VAL A 225
LEU A  83
THR A  84
 None
 0.87A 2gehA-2xf2A:
undetectable		 2gehA-2xf2A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_2
(ESTROGEN RECEPTOR)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 5 LEU A 490
ASP A 688
MET A 193
LEU A 189
 None
 1.21A 2jfaA-2xf2A:
undetectable		 2jfaA-2xf2A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 8 PHE A 125
ILE A 134
PHE A  88
GLY A 273
 None
 0.97A 2qwxA-2xf2A:
4.6
2qwxB-2xf2A:
4.2		 2qwxA-2xf2A:
14.96
2qwxB-2xf2A:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_A_RALA600_2
(ESTROGEN RECEPTOR)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 5 LEU A 490
ASP A 688
MET A 193
LEU A 189
 None
 1.22A 2qxsA-2xf2A:
undetectable		 2qxsA-2xf2A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QXS_B_RALB600_2
(ESTROGEN RECEPTOR)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 5 LEU A 490
ASP A 688
MET A 193
LEU A 189
 None
 1.22A 2qxsB-2xf2A:
undetectable		 2qxsB-2xf2A:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 ILE A 545
GLY A 548
ALA A 537
VAL A 553
ASP A 574
 None
 1.16A 2yvlC-2xf2A:
2.9		 2yvlC-2xf2A:
15.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBP_A_SAMA300_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 GLY A 599
GLY A 596
ASP A 644
LEU A 623
LEU A 627
 None
 1.10A 2zbpA-2xf2A:
undetectable		 2zbpA-2xf2A:
16.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 11 THR A 170
VAL A 479
LEU A 186
ILE A 486
ALA A 462
 None
 1.24A 2zbzA-2xf2A:
undetectable		 2zbzA-2xf2A:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AY0_A_ADNA401_1
(UNCHARACTERIZED
PROTEIN MJ0883)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 10 ILE A 481
ASN A 484
ALA A 491
ASP A 478
LEU A 186
 None
 1.41A 3ay0A-2xf2A:
undetectable		 3ay0A-2xf2A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BSZ_E_RTLE177_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 11 ALA A 566
ALA A 537
VAL A 533
LEU A 551
GLN A 552
 None
 1.28A 3bszE-2xf2A:
undetectable		 3bszE-2xf2A:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 8 HIS A  64
GLY A 120
ASN A 137
PHE A 150
 3TR  A 695 ( 2.7A)
HDD  A 690 (-3.5A)
3TR  A 695 ( 2.6A)
HDD  A 690 ( 3.5A)
 1.35A 3ccfA-2xf2A:
4.1		 3ccfA-2xf2A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_A_ETSA302_1
(CARBONIC ANHYDRASE 4)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 VAL A 274
ILE A 276
VAL A 225
LEU A  83
THR A  84
 None
 0.94A 3fw3A-2xf2A:
undetectable		 3fw3A-2xf2A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FW3_B_ETSB303_1
(CARBONIC ANHYDRASE 4)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 VAL A 274
ILE A 276
VAL A 225
LEU A  83
THR A  84
 None
 0.92A 3fw3B-2xf2A:
undetectable		 3fw3B-2xf2A:
16.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 GLY A 107
ASP A 117
GLY A 120
THR A  68
 None
None
HDD  A 690 (-3.5A)
None
 0.87A 3k4vC-2xf2A:
undetectable		 3k4vC-2xf2A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9V_B_DXCB1_0
(INVASIN IPAD)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 7 ILE A 480
LEU A 483
LEU A 189
VAL A 157
 None
 0.91A 3r9vA-2xf2A:
undetectable
3r9vB-2xf2A:
undetectable		 3r9vA-2xf2A:
17.74
3r9vB-2xf2A:
17.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 11 LEU A 646
SER A 653
THR A 660
GLY A 642
ASP A 644
 None
 1.31A 3sfuC-2xf2A:
undetectable		 3sfuC-2xf2A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 PHE A 121
GLY A 136
ALA A  70
GLY A  69
MET A 309
 None
HDD  A 690 (-3.9A)
None
None
None
 1.01A 3v3oA-2xf2A:
4.2		 3v3oA-2xf2A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 PHE A 121
GLY A 136
ALA A  70
GLY A  69
MET A 309
 None
HDD  A 690 (-3.9A)
None
None
None
 1.09A 3v3oB-2xf2A:
4.2		 3v3oB-2xf2A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 11 PHE A 121
GLY A 136
ALA A  70
GLY A  69
MET A 309
 None
HDD  A 690 (-3.9A)
None
None
None
 1.19A 4a6nA-2xf2A:
3.7		 4a6nA-2xf2A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAJ_B_0HKB2000_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR M3,
LYSOZYME)		 2xf2 CATALASE
(Penicillium
janthinellum) 		3 / 3 ASN A 484
LEU A 190
PHE A 509
 None
 0.68A 4dajB-2xf2A:
undetectable		 4dajB-2xf2A:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 10 GLN A 552
VAL A 562
LEU A 535
VAL A 533
VAL A 589
 None
 0.98A 4e3hA-2xf2A:
undetectable		 4e3hA-2xf2A:
16.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 2xf2 CATALASE
(Penicillium
janthinellum) 		6 / 12 VAL A 470
SER A 468
ALA A 171
LEU A 186
VAL A 185
VAL A 494
 None
 1.46A 4ib4A-2xf2A:
undetectable		 4ib4A-2xf2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 7 LEU A 289
LEU A 290
THR A 436
SER A 434
 None
 1.03A 4ikjA-2xf2A:
undetectable
4ikjB-2xf2A:
undetectable		 4ikjA-2xf2A:
10.94
4ikjB-2xf2A:
10.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_1
(SEPIAPTERIN
REDUCTASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 LEU A 555
GLN A 547
ALA A 591
GLY A 661
LEU A 639
 None
 1.16A 4j7xB-2xf2A:
4.3		 4j7xB-2xf2A:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.46A 4jksA-2xf2A:
4.5		 4jksA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.44A 4jksB-2xf2A:
4.5		 4jksB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.45A 4jkuA-2xf2A:
5.1		 4jkuA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_2
(SUGAR KINASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.46A 4k8cB-2xf2A:
4.4		 4k8cB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_2
(SUGAR KINASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.45A 4k8kA-2xf2A:
4.4		 4k8kA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.45A 4k8kB-2xf2A:
4.6		 4k8kB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.46A 4kalA-2xf2A:
4.5		 4kalA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.44A 4kalB-2xf2A:
4.5		 4kalB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 GLY A 136
ASP A 133
PRO A 329
ARG A 347
 HDD  A 690 (-3.9A)
None
None
HDD  A 690 (-3.6A)
 1.17A 4lajA-2xf2A:
undetectable
4lajB-2xf2A:
undetectable		 4lajA-2xf2A:
20.41
4lajB-2xf2A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 GLY A 209
ASP A 133
PRO A 329
ARG A 347
 None
None
None
HDD  A 690 (-3.6A)
 0.99A 4lajA-2xf2A:
undetectable
4lajB-2xf2A:
undetectable		 4lajA-2xf2A:
20.41
4lajB-2xf2A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.46A 4lcaA-2xf2A:
4.5		 4lcaA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.45A 4lcaB-2xf2A:
4.5		 4lcaB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OBW_B_SAMB601_0
(2-METHOXY-6-POLYPREN
YL-1,4-BENZOQUINOL
METHYLASE,
MITOCHONDRIAL)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 ALA A 591
GLY A 593
ASP A 644
ILE A 545
GLY A 548
 None
 1.05A 4obwB-2xf2A:
3.5		 4obwB-2xf2A:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 5 THR A 100
THR A 123
THR A  75
ASN A 312
 None
 1.25A 4pgfB-2xf2A:
4.8		 4pgfB-2xf2A:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5R_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 ASP A 117
ALA A 168
LYS A 158
THR A 170
 None
 1.43A 4w5rA-2xf2A:
undetectable		 4w5rA-2xf2A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5T_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 ASP A 117
ALA A 168
LYS A 158
THR A 170
 None
 1.47A 4w5tA-2xf2A:
undetectable		 4w5tA-2xf2A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 LEU A 344
ASP A 341
TYR A 351
LEU A 348
 None
None
HDD  A 690 (-3.7A)
None
 0.94A 4wozA-2xf2A:
undetectable
4wozB-2xf2A:
undetectable		 4wozA-2xf2A:
17.91
4wozB-2xf2A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 5 LEU A 344
ASP A 341
TYR A 351
LEU A 348
 None
None
HDD  A 690 (-3.7A)
None
 0.98A 4wozF-2xf2A:
undetectable
4wozH-2xf2A:
undetectable		 4wozF-2xf2A:
17.91
4wozH-2xf2A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 11 VAL A 539
ASN A 540
GLY A 593
LEU A 597
SER A 614
 None
 1.32A 4zbqA-2xf2A:
undetectable		 4zbqA-2xf2A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 5 ASN A 489
SER A 496
ASP A 461
GLU A 457
 None
 1.28A 4zjlA-2xf2A:
1.3		 4zjlA-2xf2A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 5 VAL A 216
GLY A 335
ARG A 334
PHE A 418
 None
 1.07A 5d4nA-2xf2A:
undetectable
5d4nC-2xf2A:
undetectable		 5d4nA-2xf2A:
9.97
5d4nC-2xf2A:
9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_A_0HKA1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 2xf2 CATALASE
(Penicillium
janthinellum) 		3 / 3 ASN A 484
LEU A 190
PHE A 509
 None
 0.74A 5dsgA-2xf2A:
undetectable		 5dsgA-2xf2A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HP1_A_PPFA602_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 ARG A 203
ASP A 561
GLY A 559
ASP A 529
 None
 1.32A 5hp1A-2xf2A:
undetectable		 5hp1A-2xf2A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 8 LEU A 153
PHE A 143
ALA A 106
PRO A 292
 None
 0.97A 5m0oC-2xf2A:
undetectable		 5m0oC-2xf2A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 8 GLU A 365
PHE A 125
PHE A  88
LEU A 272
 None
 0.89A 5y2tB-2xf2A:
undetectable		 5y2tB-2xf2A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 VAL A 296
VAL A 301
VAL A 336
PHE A 132
GLY A 273
 None
 1.09A 6brdC-2xf2A:
undetectable		 6brdC-2xf2A:
10.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 2xf2 CATALASE
(Penicillium
janthinellum) 		3 / 3 PHE A 681
ARG A 684
GLN A 656
 None
 0.98A 6g1pB-2xf2A:
undetectable		 6g1pB-2xf2A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 VAL A 336
VAL A 333
PHE A 227
PHE A 125
PHE A  88
 None
 1.35A 6iblB-2xf2A:
2.8		 6iblB-2xf2A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 5 LEU A 367
GLN A 366
PHE A 364
PHE A 319
 None
 1.49A 6nmpP-2xf2A:
undetectable
6nmpW-2xf2A:
undetectable		 6nmpP-2xf2A:
15.66
6nmpW-2xf2A:
5.39