SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xfm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L2I_B_CCSB417_0
(ESTROGEN RECEPTOR)		 2xfm PIWI-LIKE PROTEIN 1
(Mus
musculus) 		4 / 6 PRO A 329
PHE A 343
GLU A 386
GLN A 327
 None
 1.27A 1l2iB-2xfmA:
undetectable		 1l2iB-2xfmA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUE_A_VIVA302_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 2xfm PIWI-LIKE PROTEIN 1
(Mus
musculus) 		5 / 12 ILE A 308
ILE A 323
LEU A 363
VAL A 309
PHE A 296
 A  B   5 ( 2.9A)
None
None
None
None
 0.96A 5mueA-2xfmA:
undetectable		 5mueA-2xfmA:
21.83