SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xgo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 9 LEU A 328
LEU A 231
VAL A 208
GLY A 209
LEU A 556
 None
 1.22A 1e7aB-2xgoA:
undetectable		 1e7aB-2xgoA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4008_1
(SERUM ALBUMIN)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 8 LEU A 303
LEU A 272
ALA A 275
LYS A 276
 None
 0.81A 1e7cA-2xgoA:
undetectable		 1e7cA-2xgoA:
23.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MZ9_A_VDYA1002_4
(CARTILAGE OLIGOMERIC
MATRIX PROTEIN)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 LEU A 495
VAL A 479
CYH A 477
ALA A 454
 None
 1.14A 1mz9D-2xgoA:
undetectable		 1mz9D-2xgoA:
6.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 10 TYR A 447
SER A 356
PHE A 543
LEU A 473
VAL A 479
 ZKD  A1569 (-4.0A)
None
None
None
None
 1.40A 1q23E-2xgoA:
undetectable		 1q23E-2xgoA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 11 TYR A 447
SER A 356
PHE A 543
LEU A 473
VAL A 479
 ZKD  A1569 (-4.0A)
None
None
None
None
 1.41A 1q23J-2xgoA:
undetectable		 1q23J-2xgoA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UKB_A_BEZA1301_0
(2-HYDROXY-6-OXO-7-ME
THYLOCTA-2,4-DIENOAT
E HYDROLASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 6 LEU A 422
PHE A 425
ALA A 426
LEU A 411
 None
 0.77A 1ukbA-2xgoA:
undetectable		 1ukbA-2xgoA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 7 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.03A 1v55C-2xgoA:
undetectable
1v55J-2xgoA:
undetectable		 1v55C-2xgoA:
16.90
1v55J-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_A_9CRA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 549
PHE A 228
LEU A 231
ALA A 230
LEU A 328
 None
 1.03A 1xdkA-2xgoA:
undetectable		 1xdkA-2xgoA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_E_9CRE1500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 549
PHE A 228
LEU A 231
ALA A 230
LEU A 328
 None
 1.03A 1xdkE-2xgoA:
undetectable		 1xdkE-2xgoA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_A_4AXA605_1
(ALANINE RACEMASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 8 PHE A 457
CYH A 382
TYR A 447
TYR A 451
 None
None
ZKD  A1569 (-4.0A)
None
 1.24A 1xqlA-2xgoA:
2.5
1xqlB-2xgoA:
2.2		 1xqlA-2xgoA:
23.16
1xqlB-2xgoA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XQL_B_4AXB505_1
(ALANINE RACEMASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 8 TYR A 447
TYR A 451
PHE A 457
CYH A 382
 ZKD  A1569 (-4.0A)
None
None
None
 1.22A 1xqlA-2xgoA:
2.5
1xqlB-2xgoA:
2.2		 1xqlA-2xgoA:
23.16
1xqlB-2xgoA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y4L_B_SVRB301_1
(PHOSPHOLIPASE A2
HOMOLOG 2)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 LEU A 222
GLY A 214
GLY A 216
GLY A 250
PRO A 445
 ZKD  A1569 (-4.4A)
None
None
None
None
 1.17A 1y4lA-2xgoA:
undetectable		 1y4lA-2xgoA:
11.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 7 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.02A 2eijC-2xgoA:
undetectable
2eijJ-2xgoA:
undetectable		 2eijC-2xgoA:
16.90
2eijJ-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 7 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 0.95A 2eimC-2xgoA:
undetectable
2eimJ-2xgoA:
undetectable		 2eimC-2xgoA:
16.90
2eimJ-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 6 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.10A 2einP-2xgoA:
undetectable
2einW-2xgoA:
undetectable		 2einP-2xgoA:
16.90
2einW-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 PHE A 287
PHE A 210
TRP A 312
GLY A 553
 None
 1.43A 2qmzA-2xgoA:
4.1
2qmzB-2xgoA:
4.1		 2qmzA-2xgoA:
18.30
2qmzB-2xgoA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRH_A_NIOA200_1
(PROTEIN HP0721)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 7 ILE A 278
THR A 274
GLN A 309
LEU A 303
 None
 0.92A 2xrhA-2xgoA:
undetectable		 2xrhA-2xgoA:
11.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 7 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.01A 3ag2C-2xgoA:
undetectable		 3ag2C-2xgoA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 8 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 0.99A 3asoC-2xgoA:
undetectable
3asoJ-2xgoA:
undetectable		 3asoC-2xgoA:
16.90
3asoJ-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1271_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 7 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.04A 3asoP-2xgoA:
undetectable
3asoW-2xgoA:
undetectable		 3asoP-2xgoA:
16.90
3asoW-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 549
PHE A 228
LEU A 231
ALA A 230
LEU A 328
 None
 1.02A 3dzyA-2xgoA:
undetectable		 3dzyA-2xgoA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZY_A_9CRA463_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 549
PHE A 228
LEU A 231
ALA A 230
VAL A 310
 None
 1.11A 3dzyA-2xgoA:
undetectable		 3dzyA-2xgoA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 166
GLY A 293
GLY A 294
ARG A 184
LEU A 132
 None
 1.07A 3m6vA-2xgoA:
2.2		 3m6vA-2xgoA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 166
GLY A 293
GLY A 294
ARG A 184
LEU A 132
 None
 1.07A 3m6vB-2xgoA:
2.3		 3m6vB-2xgoA:
25.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NK2_X_LDPX433_1
(6-HYDROXY-L-NICOTINE
OXIDASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 7 MET A 504
LEU A 501
LEU A 456
PHE A 512
 None
 1.28A 3nk2X-2xgoA:
1.7		 3nk2X-2xgoA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V5W_A_8PRA701_2
(G-PROTEIN COUPLED
RECEPTOR KINASE 2)		 2xgo XCOGT
(Xanthomonas
campestris) 		3 / 3 LEU A 499
MET A 504
ASP A 459
 None
 0.92A 3v5wA-2xgoA:
undetectable		 3v5wA-2xgoA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 6 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.04A 3wg7C-2xgoA:
undetectable
3wg7J-2xgoA:
undetectable		 3wg7C-2xgoA:
16.90
3wg7J-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CCQ_A_ACTA1317_0
(THIOREDOXIN
REDUCTASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		3 / 3 LEU A 257
GLU A 229
SER A 261
 None
 0.65A 4ccqA-2xgoA:
undetectable		 4ccqA-2xgoA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_B_LURB201_1
(TRANSTHYRETIN)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 8 LEU A 263
THR A 267
ALA A 244
LEU A 242
 None
 0.92A 4iizB-2xgoA:
undetectable		 4iizB-2xgoA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LMN_A_EUIA503_2
(DUAL SPECIFICITY
MITOGEN-ACTIVATED
PROTEIN KINASE
KINASE 1)		 2xgo XCOGT
(Xanthomonas
campestris) 		3 / 3 ASP A 459
VAL A 513
ASN A 496
 None
 0.49A 4lmnA-2xgoA:
undetectable		 4lmnA-2xgoA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 11 ALA A 244
VAL A 266
ASP A 265
GLY A 295
GLY A 247
 None
 1.11A 4xnxA-2xgoA:
undetectable		 4xnxA-2xgoA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 SER A 319
GLY A 320
ALA A 185
ARG A 304
GLU A 344
 None
 0.95A 4xt8A-2xgoA:
3.1		 4xt8A-2xgoA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_E_SC2E1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 2xgo XCOGT
(Xanthomonas
campestris) 		3 / 3 VAL A 162
GLN A 177
CYH A 180
 None
 0.79A 5icxA-2xgoA:
undetectable
5icxE-2xgoA:
undetectable		 5icxA-2xgoA:
17.24
5icxE-2xgoA:
2.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.08A 5iy5P-2xgoA:
undetectable
5iy5W-2xgoA:
undetectable		 5iy5P-2xgoA:
16.55
5iy5W-2xgoA:
7.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAN_A_9CRA503_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 549
PHE A 228
LEU A 231
ALA A 230
LEU A 328
 None
 0.97A 5uanA-2xgoA:
undetectable		 5uanA-2xgoA:
21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB309_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 2xgo XCOGT
(Xanthomonas
campestris) 		3 / 3 TYR A 447
ALA A 472
TYR A 451
 ZKD  A1569 (-4.0A)
None
None
 0.83A 5uunB-2xgoA:
undetectable		 5uunB-2xgoA:
19.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_A_C2FA3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 ASN A 384
ASP A 459
ASP A 509
ASN A 390
 None
 1.10A 5vooA-2xgoA:
2.1		 5vooA-2xgoA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_C_C2FC702_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 ASN A 384
ASP A 459
ASP A 509
ASN A 390
 None
 1.12A 5vooC-2xgoA:
2.6		 5vooC-2xgoA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_1
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 ASN A 384
ASP A 459
ASP A 509
ASN A 390
 None
 1.15A 5vooE-2xgoA:
2.4		 5vooE-2xgoA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 6 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.06A 5w97C-2xgoA:
undetectable
5w97J-2xgoA:
undetectable		 5w97C-2xgoA:
16.90
5w97J-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 6 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.01A 5x19P-2xgoA:
undetectable		 5x19P-2xgoA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.01A 5x1bP-2xgoA:
undetectable		 5x1bP-2xgoA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.12A 5x1fC-2xgoA:
undetectable
5x1fJ-2xgoA:
undetectable		 5x1fC-2xgoA:
16.90
5x1fJ-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 7 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.02A 5x1fP-2xgoA:
undetectable
5x1fW-2xgoA:
undetectable		 5x1fP-2xgoA:
16.90
5x1fW-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 PHE A 548
LEU A 313
VAL A 491
GLY A 329
LEU A 556
 None
 1.28A 5x23A-2xgoA:
undetectable		 5x23A-2xgoA:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.06A 5xdxC-2xgoA:
undetectable
5xdxJ-2xgoA:
undetectable		 5xdxC-2xgoA:
16.75
5xdxJ-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 2xgo XCOGT
(Xanthomonas
campestris) 		4 / 5 ARG A 532
LEU A 536
PHE A 543
LEU A 501
 None
 1.09A 5xdxP-2xgoA:
undetectable
5xdxW-2xgoA:
undetectable		 5xdxP-2xgoA:
16.75
5xdxW-2xgoA:
7.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 549
PHE A 228
LEU A 231
ALA A 230
LEU A 328
 None
 0.98A 5z12B-2xgoA:
undetectable		 5z12B-2xgoA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_C_9CRC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 549
PHE A 228
LEU A 231
ALA A 230
LEU A 328
 None
 0.98A 5z12C-2xgoA:
undetectable		 5z12C-2xgoA:
8.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A5Z_L_9CRL501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2xgo XCOGT
(Xanthomonas
campestris) 		5 / 12 ALA A 549
PHE A 228
LEU A 231
ALA A 230
LEU A 328
 None
 0.97A 6a5zL-2xgoA:
undetectable		 6a5zL-2xgoA:
9.56