SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xgt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_B_HISB450_0
(HISTIDYL-TRNA
SYNTHETASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ARG A 321
GLU A 340
TYR A 448
GLY A 475
GLY A 515
 NSS  A1550 (-2.9A)
None
None
NSS  A1550 ( 4.1A)
None
 1.01A 1httB-2xgtA:
14.5		 1httB-2xgtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HTT_D_HISD450_0
(HISTIDYL-TRNA
SYNTHETASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ARG A 321
GLU A 340
TYR A 448
GLY A 475
GLY A 515
 NSS  A1550 (-2.9A)
None
None
NSS  A1550 ( 4.1A)
None
 1.06A 1httD-2xgtA:
14.5		 1httD-2xgtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XIU_B_9CRB202_1
(RXR-LIKE PROTEIN)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ALA A 250
ALA A 251
LEU A 527
ALA A 370
LEU A 520
 None
 1.00A 1xiuB-2xgtA:
undetectable		 1xiuB-2xgtA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOM_B_CIOB601_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 THR A 174
ILE A 133
MET A 136
PHE A 146
MET A 144
 None
 1.42A 1xomB-2xgtA:
undetectable		 1xomB-2xgtA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 9 LEU A 527
PHE A 523
LEU A 374
LEU A 365
ALA A 250
 None
 1.40A 2bxeA-2xgtA:
undetectable		 2bxeA-2xgtA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1375_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		3 / 3 LEU A 503
TYR A 502
GLN A 505
 None
 0.67A 2wekA-2xgtA:
undetectable		 2wekA-2xgtA:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_A_VDYA6178_1
(VITAMIN D
HYDROXYLASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 11 THR A 428
LEU A 464
ILE A 472
VAL A 361
PRO A 384
 None
 1.14A 3a51A-2xgtA:
undetectable		 3a51A-2xgtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_D_VDYD6178_1
(VITAMIN D
HYDROXYLASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 THR A 428
LEU A 464
ILE A 472
VAL A 361
PRO A 384
 None
 1.13A 3a51D-2xgtA:
undetectable		 3a51D-2xgtA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APW_B_DP0B190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ILE A 344
LEU A 303
GLU A 340
PHE A 259
TYR A 264
 None
 1.46A 3apwB-2xgtA:
undetectable		 3apwB-2xgtA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ALA A 250
ALA A 251
LEU A 527
ALA A 370
LEU A 520
 None
 0.97A 3h0aA-2xgtA:
undetectable		 3h0aA-2xgtA:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_A_CELA682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ALA A 223
VAL A 235
GLY A 238
ALA A 241
LEU A 244
 None
 1.05A 3ln1A-2xgtA:
undetectable		 3ln1A-2xgtA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_B_CELB682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ALA A 223
VAL A 235
GLY A 238
ALA A 241
LEU A 244
 None
 1.04A 3ln1B-2xgtA:
undetectable		 3ln1B-2xgtA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_C_CELC682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ALA A 223
VAL A 235
GLY A 238
ALA A 241
LEU A 244
 None
 1.04A 3ln1C-2xgtA:
undetectable		 3ln1C-2xgtA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ALA A 223
VAL A 235
GLY A 238
ALA A 241
LEU A 244
 None
 1.05A 3ln1D-2xgtA:
undetectable		 3ln1D-2xgtA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 10 VAL A 157
ILE A 180
ILE A 206
VAL A 172
VAL A 178
 None
 1.09A 3me6A-2xgtA:
undetectable		 3me6A-2xgtA:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		3 / 3 HIS A 134
ARG A 149
GLU A 239
 None
 1.18A 3qf1A-2xgtA:
undetectable		 3qf1A-2xgtA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		3 / 3 ARG A 506
HIS A 513
TYR A 502
 None
 1.10A 4fu8A-2xgtA:
undetectable		 4fu8A-2xgtA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		3 / 3 ARG A 506
HIS A 513
TYR A 502
 None
 1.16A 4fu9A-2xgtA:
undetectable		 4fu9A-2xgtA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		4 / 6 GLU A 421
GLU A 424
ARG A 522
GLU A 471
 None
None
NSS  A1550 (-4.1A)
MG  A1551 ( 2.6A)
 1.34A 4kr3A-2xgtA:
11.4		 4kr3A-2xgtA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PM5_A_CE3A301_2
(BETA-LACTAMASE
CTX-M-14)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		3 / 3 CYH A 341
PRO A 512
ASP A 348
 None
 0.99A 4pm5A-2xgtA:
undetectable		 4pm5A-2xgtA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 LEU A 518
LEU A 364
PRO A 384
PHE A 523
ARG A 248
 None
 1.42A 5dlvA-2xgtA:
undetectable		 5dlvA-2xgtA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 LEU A 518
LEU A 364
PRO A 384
PHE A 523
ARG A 248
 None
 1.43A 5dlvB-2xgtA:
undetectable		 5dlvB-2xgtA:
18.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ARG A 321
GLU A 340
TYR A 448
GLY A 475
GLY A 515
 NSS  A1550 (-2.9A)
None
None
NSS  A1550 ( 4.1A)
None
 1.01A 5e3iA-2xgtA:
14.3		 5e3iA-2xgtA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E3I_B_HISB502_0
(HISTIDINE--TRNA
LIGASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 11 ARG A 321
GLU A 340
TYR A 448
GLY A 475
GLY A 515
 NSS  A1550 (-2.9A)
None
None
NSS  A1550 ( 4.1A)
None
 1.04A 5e3iB-2xgtA:
14.1		 5e3iB-2xgtA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESE_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		4 / 8 LEU A 485
PHE A 489
THR A 275
LEU A 301
 None
 0.86A 5eseA-2xgtA:
undetectable		 5eseA-2xgtA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_A_CELA602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ALA A 223
VAL A 235
GLY A 238
ALA A 241
LEU A 244
 None
 1.05A 5jw1A-2xgtA:
undetectable		 5jw1A-2xgtA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ALA A 223
VAL A 235
GLY A 238
ALA A 241
LEU A 244
 None
 1.02A 5jw1B-2xgtA:
undetectable		 5jw1B-2xgtA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NN8_A_ACRA1016_1
(LYSOSOMAL
ALPHA-GLUCOSIDASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		4 / 5 ASP A 429
GLY A 470
PRO A 467
TRP A 526
 None
 1.42A 5nn8A-2xgtA:
0.3		 5nn8A-2xgtA:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_A_BZMA301_0
(ISATIN HYDROLASE A)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ILE A 180
LEU A 199
VAL A 178
GLY A 131
ASP A 150
 None
 1.14A 5nnaA-2xgtA:
undetectable		 5nnaA-2xgtA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_B_BZMB301_0
(ISATIN HYDROLASE A)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ILE A 180
LEU A 199
VAL A 178
GLY A 131
ASP A 150
 None
 1.12A 5nnaB-2xgtA:
undetectable		 5nnaB-2xgtA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_C_BZMC301_0
(ISATIN HYDROLASE A)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ILE A 180
LEU A 199
VAL A 178
GLY A 131
ASP A 150
 None
 1.11A 5nnaC-2xgtA:
undetectable		 5nnaC-2xgtA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNA_D_BZMD301_0
(ISATIN HYDROLASE A)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 ILE A 180
LEU A 199
VAL A 178
GLY A 131
ASP A 150
 None
 1.14A 5nnaD-2xgtA:
undetectable		 5nnaD-2xgtA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 10 GLN A 297
GLY A 475
GLY A 517
VAL A 277
ALA A 446
 None
NSS  A1550 ( 4.1A)
NSS  A1550 (-3.7A)
None
None
 1.16A 5o96E-2xgtA:
undetectable
5o96F-2xgtA:
undetectable		 5o96E-2xgtA:
20.00
5o96F-2xgtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		3 / 3 HIS A 403
GLU A 402
TRP A 399
 None
 1.01A 5odiD-2xgtA:
undetectable		 5odiD-2xgtA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		3 / 3 HIS A 403
GLU A 402
TRP A 399
 None
 1.05A 5odqD-2xgtA:
undetectable		 5odqD-2xgtA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODR_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		3 / 3 HIS A 403
GLU A 402
TRP A 399
 None
 0.97A 5odrD-2xgtA:
undetectable		 5odrD-2xgtA:
17.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		6 / 10 ARG A 321
GLU A 323
HIS A 330
GLY A 519
ARG A 522
ILE A 533
 NSS  A1550 (-2.9A)
NSS  A1550 (-3.5A)
NSS  A1550 (-4.6A)
NSS  A1550 (-3.5A)
NSS  A1550 (-4.1A)
None
 0.64A 6bniA-2xgtA:
30.6		 6bniA-2xgtA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_A_ADNA602_1
(LYSINE--TRNA LIGASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		6 / 10 GLU A 323
HIS A 330
GLU A 471
GLY A 519
ARG A 522
ILE A 533
 NSS  A1550 (-3.5A)
NSS  A1550 (-4.6A)
MG  A1551 ( 2.6A)
NSS  A1550 (-3.5A)
NSS  A1550 (-4.1A)
None
 0.70A 6bniA-2xgtA:
30.6		 6bniA-2xgtA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BNI_B_ADNB602_1
(LYSINE--TRNA LIGASE)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		7 / 10 ARG A 321
GLU A 323
HIS A 330
GLU A 471
GLY A 519
ARG A 522
ILE A 533
 NSS  A1550 (-2.9A)
NSS  A1550 (-3.5A)
NSS  A1550 (-4.6A)
MG  A1551 ( 2.6A)
NSS  A1550 (-3.5A)
NSS  A1550 (-4.1A)
None
 0.75A 6bniB-2xgtA:
30.6		 6bniB-2xgtA:
10.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MD4_A_BRLA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2xgt ASPARAGINYL-TRNA
SYNTHETASE,
CYTOPLASMIC
(Brugia
malayi) 		5 / 12 GLY A 279
HIS A 336
LEU A 301
ILE A 494
TYR A 334
 None
NSS  A1550 (-4.2A)
None
None
NSS  A1550 (-3.5A)
 1.19A 6md4A-2xgtA:
undetectable		 6md4A-2xgtA:
10.40