SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xgv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC2_0
(N8-ACTINOMYCIN D)		 2xgv PSIV CAPSID
N-TERMINAL DOMAIN
(Microcebus
murinus) 		3 / 3 THR A  36
PRO A  34
THR A  38
 None
 0.69A 209dC-2xgvA:
undetectable		 209dC-2xgvA:
8.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A15_A_NCAA1001_0
(HYPOTHETICAL PROTEIN
RV0760C)		 2xgv PSIV CAPSID
N-TERMINAL DOMAIN
(Microcebus
murinus) 		5 / 11 VAL A 116
TRP A 120
ASP A  81
ILE A  95
LEU A  88
 None
 1.21A 2a15A-2xgvA:
undetectable		 2a15A-2xgvA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PEV_B_ADNB501_2
(MEMBRANE LIPOPROTEIN
FAMILY PROTEIN)		 2xgv PSIV CAPSID
N-TERMINAL DOMAIN
(Microcebus
murinus) 		3 / 3 PRO A   1
LEU A  47
GLN A  54
 None
 0.57A 4pevB-2xgvA:
undetectable		 4pevB-2xgvA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 2xgv PSIV CAPSID
N-TERMINAL DOMAIN
(Microcebus
murinus) 		4 / 6 TYR A  39
TRP A  22
LEU A  56
LEU A 125
 None
 1.35A 5xooA-2xgvA:
undetectable		 5xooA-2xgvA:
25.23