SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xhy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 LEU A 191
ILE A  51
GLU A 203
PRO A 190
 None
 1.17A 1ditH-2xhyA:
undetectable
1ditP-2xhyA:
undetectable		 1ditH-2xhyA:
20.71
1ditP-2xhyA:
3.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 1k2rA-2xhyA:
undetectable
1k2rB-2xhyA:
undetectable		 1k2rA-2xhyA:
20.36
1k2rB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.43A 1k2rA-2xhyA:
undetectable
1k2rB-2xhyA:
undetectable		 1k2rA-2xhyA:
20.36
1k2rB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.43A 1k2sA-2xhyA:
undetectable
1k2sB-2xhyA:
undetectable		 1k2sA-2xhyA:
20.36
1k2sB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.40A 1k2sA-2xhyA:
undetectable
1k2sB-2xhyA:
undetectable		 1k2sA-2xhyA:
20.36
1k2sB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.45A 1k2tA-2xhyA:
0.0
1k2tB-2xhyA:
undetectable		 1k2tA-2xhyA:
20.36
1k2tB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.44A 1k2tA-2xhyA:
0.0
1k2tB-2xhyA:
undetectable		 1k2tA-2xhyA:
20.36
1k2tB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.44A 1k2uA-2xhyA:
undetectable
1k2uB-2xhyA:
undetectable		 1k2uA-2xhyA:
20.36
1k2uB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2U_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.43A 1k2uA-2xhyA:
undetectable
1k2uB-2xhyA:
undetectable		 1k2uA-2xhyA:
20.36
1k2uB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 1lzxA-2xhyA:
undetectable
1lzxB-2xhyA:
undetectable		 1lzxA-2xhyA:
20.36
1lzxB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 1lzxA-2xhyA:
undetectable
1lzxB-2xhyA:
undetectable		 1lzxA-2xhyA:
20.36
1lzxB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 1lzzA-2xhyA:
undetectable
1lzzB-2xhyA:
undetectable		 1lzzA-2xhyA:
20.36
1lzzB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 1lzzA-2xhyA:
undetectable
1lzzB-2xhyA:
undetectable		 1lzzA-2xhyA:
20.36
1lzzB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 1m00A-2xhyA:
0.0
1m00B-2xhyA:
undetectable		 1m00A-2xhyA:
20.36
1m00B-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 1m00A-2xhyA:
0.0
1m00B-2xhyA:
undetectable		 1m00A-2xhyA:
20.36
1m00B-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 1mmvA-2xhyA:
undetectable
1mmvB-2xhyA:
undetectable		 1mmvA-2xhyA:
20.36
1mmvB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.43A 1mmvA-2xhyA:
undetectable
1mmvB-2xhyA:
undetectable		 1mmvA-2xhyA:
20.36
1mmvB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 1mmwA-2xhyA:
undetectable
1mmwB-2xhyA:
undetectable		 1mmwA-2xhyA:
20.36
1mmwB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 1mmwA-2xhyA:
undetectable
1mmwB-2xhyA:
undetectable		 1mmwA-2xhyA:
20.36
1mmwB-2xhyA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 1om4A-2xhyA:
undetectable
1om4B-2xhyA:
undetectable		 1om4A-2xhyA:
20.63
1om4B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 1om4A-2xhyA:
undetectable
1om4B-2xhyA:
undetectable		 1om4A-2xhyA:
20.63
1om4B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 8 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 1om5A-2xhyA:
undetectable
1om5B-2xhyA:
undetectable		 1om5A-2xhyA:
20.28
1om5B-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM5_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.43A 1om5A-2xhyA:
undetectable
1om5B-2xhyA:
undetectable		 1om5A-2xhyA:
20.28
1om5B-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 1p6hA-2xhyA:
undetectable
1p6hB-2xhyA:
undetectable		 1p6hA-2xhyA:
20.28
1p6hB-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.42A 1p6hA-2xhyA:
undetectable
1p6hB-2xhyA:
undetectable		 1p6hA-2xhyA:
20.28
1p6hB-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 1p6iA-2xhyA:
0.1
1p6iB-2xhyA:
undetectable		 1p6iA-2xhyA:
20.28
1p6iB-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 1p6iA-2xhyA:
0.0
1p6iB-2xhyA:
undetectable		 1p6iA-2xhyA:
20.28
1p6iB-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 1p6jA-2xhyA:
undetectable
1p6jB-2xhyA:
undetectable		 1p6jA-2xhyA:
20.28
1p6jB-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 1p6jA-2xhyA:
undetectable
1p6jB-2xhyA:
undetectable		 1p6jA-2xhyA:
20.28
1p6jB-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 1p6kA-2xhyA:
undetectable
1p6kB-2xhyA:
undetectable		 1p6kA-2xhyA:
20.92
1p6kB-2xhyA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 1p6kA-2xhyA:
undetectable
1p6kB-2xhyA:
undetectable		 1p6kA-2xhyA:
20.92
1p6kB-2xhyA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 1rs6A-2xhyA:
undetectable
1rs6B-2xhyA:
undetectable		 1rs6A-2xhyA:
20.28
1rs6B-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 8 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 1rs6A-2xhyA:
undetectable
1rs6B-2xhyA:
undetectable		 1rs6A-2xhyA:
20.28
1rs6B-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 1rs7A-2xhyA:
undetectable
1rs7B-2xhyA:
undetectable		 1rs7A-2xhyA:
20.28
1rs7B-2xhyA:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 TYR A 400
HIS A 404
LEU A 358
TYR A 317
 None
 1.15A 1tuvA-2xhyA:
undetectable		 1tuvA-2xhyA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_B_CHDB4085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.35A 1v54A-2xhyA:
0.0
1v54B-2xhyA:
0.0
1v54T-2xhyA:
0.0		 1v54A-2xhyA:
20.62
1v54B-2xhyA:
18.60
1v54T-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.33A 1v54G-2xhyA:
0.0
1v54N-2xhyA:
0.0
1v54O-2xhyA:
0.0		 1v54G-2xhyA:
10.37
1v54N-2xhyA:
20.62
1v54O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.32A 1v55G-2xhyA:
undetectable
1v55N-2xhyA:
0.0
1v55O-2xhyA:
undetectable		 1v55G-2xhyA:
10.37
1v55N-2xhyA:
20.62
1v55O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 MET A 211
VAL A 214
LEU A 215
PHE A 219
 None
 1.11A 1x8vA-2xhyA:
undetectable		 1x8vA-2xhyA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZVL_A_H4BA900_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.42A 1zvlA-2xhyA:
undetectable
1zvlB-2xhyA:
undetectable		 1zvlA-2xhyA:
20.48
1zvlB-2xhyA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 1zzqA-2xhyA:
undetectable
1zzqB-2xhyA:
undetectable		 1zzqA-2xhyA:
21.35
1zzqB-2xhyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.44A 1zzqA-2xhyA:
undetectable
1zzqB-2xhyA:
undetectable		 1zzqA-2xhyA:
21.35
1zzqB-2xhyA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.32A 2dyrG-2xhyA:
0.0
2dyrN-2xhyA:
0.0
2dyrO-2xhyA:
0.0		 2dyrG-2xhyA:
10.37
2dyrN-2xhyA:
20.62
2dyrO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.33A 2eijG-2xhyA:
0.0
2eijN-2xhyA:
0.0
2eijO-2xhyA:
0.0		 2eijG-2xhyA:
10.37
2eijN-2xhyA:
20.62
2eijO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.34A 2eikG-2xhyA:
0.0
2eikN-2xhyA:
0.0
2eikO-2xhyA:
0.0		 2eikG-2xhyA:
10.37
2eikN-2xhyA:
20.62
2eikO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.35A 2eilG-2xhyA:
0.0
2eilN-2xhyA:
0.0
2eilO-2xhyA:
0.0		 2eilG-2xhyA:
10.37
2eilN-2xhyA:
20.62
2eilO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CHDN1604_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.29A 2eimG-2xhyA:
0.0
2eimN-2xhyA:
0.0
2eimO-2xhyA:
0.0		 2eimG-2xhyA:
10.37
2eimN-2xhyA:
20.62
2eimO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 8 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 2g6hA-2xhyA:
undetectable
2g6hB-2xhyA:
undetectable		 2g6hA-2xhyA:
20.72
2g6hB-2xhyA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 2g6hA-2xhyA:
undetectable
2g6hB-2xhyA:
undetectable		 2g6hA-2xhyA:
20.72
2g6hB-2xhyA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 2g6kA-2xhyA:
undetectable
2g6kB-2xhyA:
undetectable		 2g6kA-2xhyA:
20.72
2g6kB-2xhyA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.44A 2g6kA-2xhyA:
undetectable
2g6kB-2xhyA:
undetectable		 2g6kA-2xhyA:
20.72
2g6kB-2xhyA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.45A 2g6mA-2xhyA:
undetectable
2g6mB-2xhyA:
undetectable		 2g6mA-2xhyA:
20.72
2g6mB-2xhyA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 2g6mA-2xhyA:
undetectable
2g6mB-2xhyA:
undetectable		 2g6mA-2xhyA:
20.72
2g6mB-2xhyA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 GLY A 455
THR A 454
ASP A 456
ASN A 448
 None
 1.03A 2g70B-2xhyA:
undetectable		 2g70B-2xhyA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 2hx3A-2xhyA:
undetectable
2hx3B-2xhyA:
undetectable		 2hx3A-2xhyA:
20.63
2hx3B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 2hx4A-2xhyA:
undetectable
2hx4B-2xhyA:
undetectable		 2hx4A-2xhyA:
20.63
2hx4B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 2hx4A-2xhyA:
undetectable
2hx4B-2xhyA:
undetectable		 2hx4A-2xhyA:
20.63
2hx4B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X0Y_A_X0TA1625_1
(O-GLCNACASE NAGJ)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 12 TYR A 194
VAL A 200
TYR A 201
VAL A 214
VAL A 153
 None
 1.46A 2x0yA-2xhyA:
14.5		 2x0yA-2xhyA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_G_CHDG1085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.36A 2y69G-2xhyA:
0.0
2y69N-2xhyA:
0.0
2y69O-2xhyA:
0.0		 2y69G-2xhyA:
11.06
2y69N-2xhyA:
20.62
2y69O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_T_CHDT1085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.36A 2y69A-2xhyA:
0.1
2y69B-2xhyA:
0.0
2y69T-2xhyA:
0.0		 2y69A-2xhyA:
20.62
2y69B-2xhyA:
18.60
2y69T-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		3 / 3 ASP A 115
PHE A 118
LEU A 122
 None
 0.38A 2zi9A-2xhyA:
undetectable		 2zi9A-2xhyA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_B_CHDB1086_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.32A 2zxwA-2xhyA:
0.0
2zxwB-2xhyA:
0.0
2zxwT-2xhyA:
0.0		 2zxwA-2xhyA:
20.62
2zxwB-2xhyA:
18.60
2zxwT-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_G_CHDG86_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 6A2
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.36A 2zxwG-2xhyA:
0.0
2zxwN-2xhyA:
0.0
2zxwO-2xhyA:
0.0		 2zxwG-2xhyA:
10.37
2zxwN-2xhyA:
20.62
2zxwO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.38A 3abkA-2xhyA:
0.0
3abkB-2xhyA:
0.0
3abkT-2xhyA:
0.0		 3abkA-2xhyA:
20.62
3abkB-2xhyA:
18.60
3abkT-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.34A 3abkG-2xhyA:
0.0
3abkN-2xhyA:
0.0
3abkO-2xhyA:
0.0		 3abkG-2xhyA:
10.37
3abkN-2xhyA:
20.62
3abkO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.36A 3ablA-2xhyA:
0.0
3ablB-2xhyA:
undetectable
3ablT-2xhyA:
undetectable		 3ablA-2xhyA:
20.62
3ablB-2xhyA:
18.60
3ablT-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.35A 3ablG-2xhyA:
0.0
3ablN-2xhyA:
0.0
3ablO-2xhyA:
0.0		 3ablG-2xhyA:
10.37
3ablN-2xhyA:
20.62
3ablO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_B_CHDB1086_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.40A 3abmA-2xhyA:
0.0
3abmB-2xhyA:
0.0
3abmT-2xhyA:
0.0		 3abmA-2xhyA:
20.62
3abmB-2xhyA:
18.60
3abmT-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.36A 3abmG-2xhyA:
0.0
3abmN-2xhyA:
0.0
3abmO-2xhyA:
0.0		 3abmG-2xhyA:
10.37
3abmN-2xhyA:
20.62
3abmO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.35A 3ag1A-2xhyA:
0.0
3ag1B-2xhyA:
undetectable
3ag1T-2xhyA:
undetectable		 3ag1A-2xhyA:
20.62
3ag1B-2xhyA:
18.60
3ag1T-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.38A 3ag1G-2xhyA:
0.0
3ag1N-2xhyA:
0.1
3ag1O-2xhyA:
0.0		 3ag1G-2xhyA:
10.37
3ag1N-2xhyA:
20.62
3ag1O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_G_CHDG86_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.36A 3ag2G-2xhyA:
0.0
3ag2N-2xhyA:
0.1
3ag2O-2xhyA:
0.0		 3ag2G-2xhyA:
10.37
3ag2N-2xhyA:
20.62
3ag2O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.38A 3ag3A-2xhyA:
0.2
3ag3B-2xhyA:
0.0
3ag3T-2xhyA:
0.0		 3ag3A-2xhyA:
20.62
3ag3B-2xhyA:
18.60
3ag3T-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.37A 3ag3G-2xhyA:
undetectable
3ag3N-2xhyA:
undetectable
3ag3O-2xhyA:
undetectable		 3ag3G-2xhyA:
10.37
3ag3N-2xhyA:
20.62
3ag3O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 12 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.40A 3ag4A-2xhyA:
0.0
3ag4B-2xhyA:
undetectable
3ag4T-2xhyA:
undetectable		 3ag4A-2xhyA:
20.62
3ag4B-2xhyA:
18.60
3ag4T-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.35A 3ag4G-2xhyA:
0.0
3ag4N-2xhyA:
0.0
3ag4O-2xhyA:
0.0		 3ag4G-2xhyA:
10.37
3ag4N-2xhyA:
20.62
3ag4O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.39A 3asnA-2xhyA:
0.0
3asnB-2xhyA:
0.0
3asnT-2xhyA:
0.0		 3asnA-2xhyA:
20.62
3asnB-2xhyA:
18.60
3asnT-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_G_CHDG229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.35A 3asnG-2xhyA:
0.0
3asnN-2xhyA:
0.0
3asnO-2xhyA:
0.0		 3asnG-2xhyA:
10.37
3asnN-2xhyA:
20.62
3asnO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_G_CHDG229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.36A 3asoG-2xhyA:
0.0
3asoN-2xhyA:
0.0
3asoO-2xhyA:
0.0		 3asoG-2xhyA:
10.37
3asoN-2xhyA:
20.62
3asoO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3b3mA-2xhyA:
0.3
3b3mB-2xhyA:
undetectable		 3b3mA-2xhyA:
20.63
3b3mB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3b3nA-2xhyA:
undetectable
3b3nB-2xhyA:
0.1		 3b3nA-2xhyA:
20.63
3b3nB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.44A 3b3nA-2xhyA:
undetectable
3b3nB-2xhyA:
0.2		 3b3nA-2xhyA:
20.63
3b3nB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3b3oA-2xhyA:
undetectable
3b3oB-2xhyA:
undetectable		 3b3oA-2xhyA:
20.63
3b3oB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 3b3oA-2xhyA:
undetectable
3b3oB-2xhyA:
undetectable		 3b3oA-2xhyA:
20.63
3b3oB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3b3pA-2xhyA:
undetectable
3b3pB-2xhyA:
undetectable		 3b3pA-2xhyA:
20.63
3b3pB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 8 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 3b3pA-2xhyA:
undetectable
3b3pB-2xhyA:
undetectable		 3b3pA-2xhyA:
20.63
3b3pB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		3 / 3 CYH A  87
PHE A  88
PHE A  85
 None
 0.86A 3cr5X-2xhyA:
undetectable		 3cr5X-2xhyA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E23_A_SAMA221_1
(UNCHARACTERIZED
PROTEIN RPA2492)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		3 / 3 TYR A 383
ASP A 451
HIS A  45
 None
BR  A1482 ( 4.3A)
None
 0.97A 3e23A-2xhyA:
undetectable		 3e23A-2xhyA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 LEU A 365
TYR A 366
ARG A 368
LEU A 373
 None
 0.76A 3f33A-2xhyA:
undetectable		 3f33A-2xhyA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 3fc5A-2xhyA:
undetectable
3fc5B-2xhyA:
undetectable		 3fc5A-2xhyA:
21.46
3fc5B-2xhyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 3fc5A-2xhyA:
undetectable
3fc5B-2xhyA:
undetectable		 3fc5A-2xhyA:
21.46
3fc5B-2xhyA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.44A 3hsnA-2xhyA:
undetectable
3hsnB-2xhyA:
undetectable		 3hsnA-2xhyA:
20.63
3hsnB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3hsoA-2xhyA:
undetectable
3hsoB-2xhyA:
undetectable		 3hsoA-2xhyA:
20.63
3hsoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 3hsoA-2xhyA:
undetectable
3hsoB-2xhyA:
undetectable		 3hsoA-2xhyA:
20.63
3hsoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.45A 3hspA-2xhyA:
undetectable
3hspB-2xhyA:
undetectable		 3hspA-2xhyA:
20.63
3hspB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 3hspA-2xhyA:
undetectable
3hspB-2xhyA:
undetectable		 3hspA-2xhyA:
20.63
3hspB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 3jt3A-2xhyA:
undetectable
3jt3B-2xhyA:
0.4		 3jt3A-2xhyA:
20.63
3jt3B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 3jt4A-2xhyA:
undetectable
3jt4B-2xhyA:
0.0		 3jt4A-2xhyA:
20.63
3jt4B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3jt5A-2xhyA:
undetectable
3jt5B-2xhyA:
undetectable		 3jt5A-2xhyA:
20.63
3jt5B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 3jt5A-2xhyA:
undetectable
3jt5B-2xhyA:
undetectable		 3jt5A-2xhyA:
20.63
3jt5B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3jt6A-2xhyA:
undetectable
3jt6B-2xhyA:
undetectable		 3jt6A-2xhyA:
20.63
3jt6B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 3jt6A-2xhyA:
undetectable
3jt6B-2xhyA:
undetectable		 3jt6A-2xhyA:
20.63
3jt6B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 3jt7A-2xhyA:
undetectable
3jt7B-2xhyA:
undetectable		 3jt7A-2xhyA:
20.63
3jt7B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3jt8A-2xhyA:
undetectable
3jt8B-2xhyA:
0.2		 3jt8A-2xhyA:
20.63
3jt8B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 3jt8A-2xhyA:
undetectable
3jt8B-2xhyA:
0.2		 3jt8A-2xhyA:
20.63
3jt8B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 3jt9A-2xhyA:
undetectable
3jt9B-2xhyA:
undetectable		 3jt9A-2xhyA:
20.63
3jt9B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.43A 3jt9A-2xhyA:
undetectable
3jt9B-2xhyA:
undetectable		 3jt9A-2xhyA:
20.63
3jt9B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3jtaA-2xhyA:
undetectable
3jtaB-2xhyA:
0.0		 3jtaA-2xhyA:
20.63
3jtaB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 3jtaA-2xhyA:
undetectable
3jtaB-2xhyA:
0.0		 3jtaA-2xhyA:
20.63
3jtaB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 3jwsA-2xhyA:
0.3
3jwsB-2xhyA:
undetectable		 3jwsA-2xhyA:
20.63
3jwsB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 3jwuA-2xhyA:
undetectable
3jwuB-2xhyA:
undetectable		 3jwuA-2xhyA:
20.63
3jwuB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 3jx0A-2xhyA:
0.3
3jx0B-2xhyA:
undetectable		 3jx0A-2xhyA:
21.26
3jx0B-2xhyA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_B_VIBB223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 LEU A  40
LEU A 191
CYH A 195
SER A 197
 None
 1.02A 3lm8B-2xhyA:
undetectable
3lm8D-2xhyA:
undetectable		 3lm8B-2xhyA:
18.18
3lm8D-2xhyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 8 LEU A  40
LEU A 191
CYH A 195
SER A 197
 None
 1.01A 3lm8B-2xhyA:
undetectable
3lm8D-2xhyA:
1.3		 3lm8B-2xhyA:
18.18
3lm8D-2xhyA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_B_ACTB901_0
(PYRANOSE 2-OXIDASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 SER A 315
PHE A 135
HIS A 134
ASN A 179
 None
 1.35A 3lskB-2xhyA:
undetectable		 3lskB-2xhyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSK_D_ACTD901_0
(PYRANOSE 2-OXIDASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 SER A 315
PHE A 135
HIS A 134
ASN A 179
 None
 1.35A 3lskD-2xhyA:
undetectable		 3lskD-2xhyA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 3n2rA-2xhyA:
undetectable
3n2rB-2xhyA:
undetectable		 3n2rA-2xhyA:
20.63
3n2rB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 3nlmA-2xhyA:
undetectable
3nlmB-2xhyA:
0.0		 3nlmA-2xhyA:
20.63
3nlmB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 3nlnA-2xhyA:
undetectable
3nlnB-2xhyA:
undetectable		 3nlnA-2xhyA:
20.63
3nlnB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3nloA-2xhyA:
undetectable
3nloB-2xhyA:
undetectable		 3nloA-2xhyA:
20.63
3nloB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 3nloA-2xhyA:
undetectable
3nloB-2xhyA:
undetectable		 3nloA-2xhyA:
20.63
3nloB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3nlvA-2xhyA:
undetectable
3nlvB-2xhyA:
0.2		 3nlvA-2xhyA:
20.63
3nlvB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3nlvA-2xhyA:
undetectable
3nlvB-2xhyA:
0.3		 3nlvA-2xhyA:
20.63
3nlvB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 3nlwA-2xhyA:
undetectable
3nlwB-2xhyA:
0.4		 3nlwA-2xhyA:
20.63
3nlwB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 3nlwA-2xhyA:
undetectable
3nlwB-2xhyA:
0.4		 3nlwA-2xhyA:
20.63
3nlwB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 3nlxA-2xhyA:
undetectable
3nlxB-2xhyA:
undetectable		 3nlxA-2xhyA:
20.63
3nlxB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3nlzA-2xhyA:
undetectable
3nlzB-2xhyA:
undetectable		 3nlzA-2xhyA:
20.63
3nlzB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3nm0A-2xhyA:
0.3
3nm0B-2xhyA:
undetectable		 3nm0A-2xhyA:
20.63
3nm0B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3nm0A-2xhyA:
0.3
3nm0B-2xhyA:
undetectable		 3nm0A-2xhyA:
20.63
3nm0B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3nnyA-2xhyA:
0.3
3nnyB-2xhyA:
undetectable		 3nnyA-2xhyA:
20.63
3nnyB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3nnyA-2xhyA:
0.3
3nnyB-2xhyA:
undetectable		 3nnyA-2xhyA:
20.63
3nnyB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 3nnzA-2xhyA:
undetectable
3nnzB-2xhyA:
undetectable		 3nnzA-2xhyA:
20.63
3nnzB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3nnzA-2xhyA:
undetectable
3nnzB-2xhyA:
undetectable		 3nnzA-2xhyA:
20.63
3nnzB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3pneA-2xhyA:
0.0
3pneB-2xhyA:
undetectable		 3pneA-2xhyA:
20.63
3pneB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 3pnfA-2xhyA:
undetectable
3pnfB-2xhyA:
undetectable		 3pnfA-2xhyA:
20.63
3pnfB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3pngA-2xhyA:
undetectable
3pngB-2xhyA:
undetectable		 3pngA-2xhyA:
20.63
3pngB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 3pngA-2xhyA:
undetectable
3pngB-2xhyA:
undetectable		 3pngA-2xhyA:
20.63
3pngB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3q99A-2xhyA:
undetectable
3q99B-2xhyA:
0.2		 3q99A-2xhyA:
20.63
3q99B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3q9aA-2xhyA:
undetectable
3q9aB-2xhyA:
undetectable		 3q9aA-2xhyA:
20.63
3q9aB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.42A 3q9aA-2xhyA:
undetectable
3q9aB-2xhyA:
undetectable		 3q9aA-2xhyA:
20.63
3q9aB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAV_A_RAVA183_1
(FERRITIN LIGHT CHAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 LEU A 365
TYR A 366
ARG A 368
LEU A 373
 None
 0.78A 3ravA-2xhyA:
undetectable		 3ravA-2xhyA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RD0_A_EDPA175_1
(FERRITIN LIGHT CHAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 LEU A 365
TYR A 366
ARG A 368
LEU A 373
 None
 0.78A 3rd0A-2xhyA:
undetectable		 3rd0A-2xhyA:
16.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3rqjA-2xhyA:
undetectable
3rqjB-2xhyA:
undetectable		 3rqjA-2xhyA:
20.63
3rqjB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 3rqjA-2xhyA:
undetectable
3rqjB-2xhyA:
undetectable		 3rqjA-2xhyA:
20.63
3rqjB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3rqkA-2xhyA:
0.2
3rqkB-2xhyA:
0.1		 3rqkA-2xhyA:
20.63
3rqkB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3rqlA-2xhyA:
0.4
3rqlB-2xhyA:
undetectable		 3rqlA-2xhyA:
20.63
3rqlB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3rqmA-2xhyA:
undetectable
3rqmB-2xhyA:
undetectable		 3rqmA-2xhyA:
20.63
3rqmB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 3rqnA-2xhyA:
0.2
3rqnB-2xhyA:
undetectable		 3rqnA-2xhyA:
20.63
3rqnB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 3rqnA-2xhyA:
0.2
3rqnB-2xhyA:
undetectable		 3rqnA-2xhyA:
20.63
3rqnB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 4 GLY A  43
GLY A 436
THR A 434
LEU A 191
 None
None
SO4  A1481 (-4.0A)
None
 0.87A 3si7C-2xhyA:
undetectable
3si7D-2xhyA:
undetectable		 3si7C-2xhyA:
18.30
3si7D-2xhyA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_D_ACTD4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 5 LEU A 191
GLY A  43
GLY A 436
THR A 434
 None
None
None
SO4  A1481 (-4.0A)
 0.83A 3si7C-2xhyA:
undetectable
3si7D-2xhyA:
undetectable		 3si7C-2xhyA:
18.30
3si7D-2xhyA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 3svpA-2xhyA:
0.2
3svpB-2xhyA:
undetectable		 3svpA-2xhyA:
20.63
3svpB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 3svqA-2xhyA:
0.3
3svqB-2xhyA:
undetectable		 3svqA-2xhyA:
20.63
3svqB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 3tylA-2xhyA:
undetectable
3tylB-2xhyA:
undetectable		 3tylA-2xhyA:
20.63
3tylB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 3tymA-2xhyA:
undetectable
3tymB-2xhyA:
undetectable		 3tymA-2xhyA:
20.63
3tymB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 3tyoA-2xhyA:
undetectable
3tyoB-2xhyA:
undetectable		 3tyoA-2xhyA:
20.63
3tyoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_N_CLMN221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 PHE A 444
TYR A 468
VAL A 129
PHE A 374
PHE A  85
 None
 1.46A 3u9fN-2xhyA:
undetectable
3u9fO-2xhyA:
undetectable		 3u9fN-2xhyA:
17.23
3u9fO-2xhyA:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3ufoA-2xhyA:
undetectable
3ufoB-2xhyA:
0.2		 3ufoA-2xhyA:
20.63
3ufoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3ufoA-2xhyA:
undetectable
3ufoB-2xhyA:
0.2		 3ufoA-2xhyA:
20.63
3ufoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.43A 3ufpA-2xhyA:
undetectable
3ufpB-2xhyA:
undetectable		 3ufpA-2xhyA:
20.63
3ufpB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3ufpA-2xhyA:
undetectable
3ufpB-2xhyA:
undetectable		 3ufpA-2xhyA:
20.63
3ufpB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 3ufqA-2xhyA:
undetectable
3ufqB-2xhyA:
0.2		 3ufqA-2xhyA:
20.63
3ufqB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.44A 3ufrA-2xhyA:
undetectable
3ufrB-2xhyA:
undetectable		 3ufrA-2xhyA:
20.63
3ufrB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3ufsA-2xhyA:
undetectable
3ufsB-2xhyA:
undetectable		 3ufsA-2xhyA:
20.63
3ufsB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 3ufsA-2xhyA:
undetectable
3ufsB-2xhyA:
undetectable		 3ufsA-2xhyA:
20.63
3ufsB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 3uftA-2xhyA:
0.2
3uftB-2xhyA:
undetectable		 3uftA-2xhyA:
20.63
3uftB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3ufuA-2xhyA:
undetectable
3ufuB-2xhyA:
undetectable		 3ufuA-2xhyA:
20.63
3ufuB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 3ufuA-2xhyA:
undetectable
3ufuB-2xhyA:
undetectable		 3ufuA-2xhyA:
20.63
3ufuB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 3ufvA-2xhyA:
undetectable
3ufvB-2xhyA:
undetectable		 3ufvA-2xhyA:
20.63
3ufvB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 3ufwA-2xhyA:
undetectable
3ufwB-2xhyA:
0.2		 3ufwA-2xhyA:
20.63
3ufwB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 3ufwA-2xhyA:
undetectable
3ufwB-2xhyA:
0.2		 3ufwA-2xhyA:
20.63
3ufwB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.36A 3wg7G-2xhyA:
0.0
3wg7N-2xhyA:
0.0
3wg7O-2xhyA:
0.0		 3wg7G-2xhyA:
10.37
3wg7N-2xhyA:
20.62
3wg7O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.38A 3x2qA-2xhyA:
0.0
3x2qB-2xhyA:
undetectable
3x2qT-2xhyA:
undetectable		 3x2qA-2xhyA:
20.62
3x2qB-2xhyA:
18.60
3x2qT-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.34A 3x2qG-2xhyA:
0.0
3x2qN-2xhyA:
0.1
3x2qO-2xhyA:
0.0		 3x2qG-2xhyA:
10.37
3x2qN-2xhyA:
20.62
3x2qO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4c39A-2xhyA:
undetectable
4c39B-2xhyA:
undetectable		 4c39A-2xhyA:
20.63
4c39B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 4c39A-2xhyA:
undetectable
4c39B-2xhyA:
undetectable		 4c39A-2xhyA:
20.63
4c39B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 4camA-2xhyA:
undetectable
4camB-2xhyA:
undetectable		 4camA-2xhyA:
20.63
4camB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 4camA-2xhyA:
undetectable
4camB-2xhyA:
undetectable		 4camA-2xhyA:
20.63
4camB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4canA-2xhyA:
0.3
4canB-2xhyA:
undetectable		 4canA-2xhyA:
20.63
4canB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 4caoA-2xhyA:
undetectable
4caoB-2xhyA:
undetectable		 4caoA-2xhyA:
20.63
4caoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4capA-2xhyA:
0.2
4capB-2xhyA:
undetectable		 4capA-2xhyA:
20.63
4capB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4caqA-2xhyA:
undetectable
4caqB-2xhyA:
undetectable		 4caqA-2xhyA:
20.63
4caqB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4cdtA-2xhyA:
undetectable
4cdtB-2xhyA:
0.2		 4cdtA-2xhyA:
20.63
4cdtB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CDT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4cdtA-2xhyA:
undetectable
4cdtB-2xhyA:
0.2		 4cdtA-2xhyA:
20.63
4cdtB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4ctpA-2xhyA:
undetectable
4ctpB-2xhyA:
undetectable		 4ctpA-2xhyA:
20.63
4ctpB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4ctpA-2xhyA:
undetectable
4ctpB-2xhyA:
undetectable		 4ctpA-2xhyA:
20.63
4ctpB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4ctqA-2xhyA:
undetectable
4ctqB-2xhyA:
undetectable		 4ctqA-2xhyA:
20.63
4ctqB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4ctuA-2xhyA:
undetectable
4ctuB-2xhyA:
undetectable		 4ctuA-2xhyA:
20.63
4ctuB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 4ctvA-2xhyA:
0.0
4ctvB-2xhyA:
0.1		 4ctvA-2xhyA:
20.63
4ctvB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4ctvA-2xhyA:
0.0
4ctvB-2xhyA:
0.1		 4ctvA-2xhyA:
20.63
4ctvB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 4ctwA-2xhyA:
undetectable
4ctwB-2xhyA:
undetectable		 4ctwA-2xhyA:
20.63
4ctwB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4ctwA-2xhyA:
undetectable
4ctwB-2xhyA:
undetectable		 4ctwA-2xhyA:
20.63
4ctwB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4ctxA-2xhyA:
undetectable
4ctxB-2xhyA:
undetectable		 4ctxA-2xhyA:
20.63
4ctxB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 4ctxA-2xhyA:
undetectable
4ctxB-2xhyA:
undetectable		 4ctxA-2xhyA:
20.63
4ctxB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4cx5A-2xhyA:
undetectable
4cx5B-2xhyA:
undetectable		 4cx5A-2xhyA:
21.34
4cx5B-2xhyA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4cx5A-2xhyA:
undetectable
4cx5B-2xhyA:
undetectable		 4cx5A-2xhyA:
21.34
4cx5B-2xhyA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 4cx6A-2xhyA:
0.2
4cx6B-2xhyA:
undetectable		 4cx6A-2xhyA:
21.34
4cx6B-2xhyA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4cx6A-2xhyA:
0.1
4cx6B-2xhyA:
undetectable		 4cx6A-2xhyA:
21.34
4cx6B-2xhyA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 4d1nA-2xhyA:
undetectable
4d1nB-2xhyA:
undetectable		 4d1nA-2xhyA:
20.87
4d1nB-2xhyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 4d1nA-2xhyA:
undetectable
4d1nB-2xhyA:
undetectable		 4d1nA-2xhyA:
20.87
4d1nB-2xhyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.45A 4d1nC-2xhyA:
undetectable
4d1nD-2xhyA:
undetectable		 4d1nC-2xhyA:
20.87
4d1nD-2xhyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 4d1nC-2xhyA:
undetectable
4d1nD-2xhyA:
undetectable		 4d1nC-2xhyA:
20.87
4d1nD-2xhyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4d2yA-2xhyA:
undetectable
4d2yB-2xhyA:
undetectable		 4d2yA-2xhyA:
20.63
4d2yB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 4d2yA-2xhyA:
undetectable
4d2yB-2xhyA:
undetectable		 4d2yA-2xhyA:
20.63
4d2yB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4d2zA-2xhyA:
1.0
4d2zB-2xhyA:
undetectable		 4d2zA-2xhyA:
20.63
4d2zB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 4d30A-2xhyA:
undetectable
4d30B-2xhyA:
0.2		 4d30A-2xhyA:
20.63
4d30B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D31_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 4d31A-2xhyA:
undetectable
4d31B-2xhyA:
undetectable		 4d31A-2xhyA:
20.63
4d31B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4d32A-2xhyA:
undetectable
4d32B-2xhyA:
0.0		 4d32A-2xhyA:
20.63
4d32B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4d3bA-2xhyA:
undetectable
4d3bB-2xhyA:
undetectable		 4d3bA-2xhyA:
20.63
4d3bB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 4d3bA-2xhyA:
undetectable
4d3bB-2xhyA:
undetectable		 4d3bA-2xhyA:
20.63
4d3bB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 4d7oA-2xhyA:
undetectable
4d7oB-2xhyA:
undetectable		 4d7oA-2xhyA:
20.63
4d7oB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 4euxA-2xhyA:
undetectable
4euxB-2xhyA:
undetectable		 4euxA-2xhyA:
20.63
4euxB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 4euxA-2xhyA:
undetectable
4euxB-2xhyA:
undetectable		 4euxA-2xhyA:
20.63
4euxB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 4fvwA-2xhyA:
undetectable
4fvwB-2xhyA:
0.2		 4fvwA-2xhyA:
20.63
4fvwB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.43A 4fvwA-2xhyA:
undetectable
4fvwB-2xhyA:
0.2		 4fvwA-2xhyA:
20.63
4fvwB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 4fvxA-2xhyA:
undetectable
4fvxB-2xhyA:
0.2		 4fvxA-2xhyA:
20.63
4fvxB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.44A 4fvxA-2xhyA:
undetectable
4fvxB-2xhyA:
0.2		 4fvxA-2xhyA:
20.63
4fvxB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 4fvyA-2xhyA:
undetectable
4fvyB-2xhyA:
undetectable		 4fvyA-2xhyA:
20.63
4fvyB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 4fvyA-2xhyA:
undetectable
4fvyB-2xhyA:
undetectable		 4fvyA-2xhyA:
20.63
4fvyB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 4fvzA-2xhyA:
undetectable
4fvzB-2xhyA:
undetectable		 4fvzA-2xhyA:
20.63
4fvzB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 4fw0A-2xhyA:
undetectable
4fw0B-2xhyA:
undetectable		 4fw0A-2xhyA:
20.63
4fw0B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4gqeA-2xhyA:
undetectable
4gqeB-2xhyA:
undetectable		 4gqeA-2xhyA:
20.63
4gqeB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.44A 4gqeA-2xhyA:
undetectable
4gqeB-2xhyA:
undetectable		 4gqeA-2xhyA:
20.63
4gqeB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4jsiA-2xhyA:
undetectable
4jsiB-2xhyA:
0.2		 4jsiA-2xhyA:
20.63
4jsiB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 4jsjA-2xhyA:
undetectable
4jsjB-2xhyA:
0.0		 4jsjA-2xhyA:
20.63
4jsjB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4k5dA-2xhyA:
0.0
4k5dB-2xhyA:
undetectable		 4k5dA-2xhyA:
20.63
4k5dB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4k5eA-2xhyA:
undetectable
4k5eB-2xhyA:
0.1		 4k5eA-2xhyA:
20.62
4k5eB-2xhyA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4k5eA-2xhyA:
undetectable
4k5eB-2xhyA:
0.1		 4k5eA-2xhyA:
20.62
4k5eB-2xhyA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4k5fA-2xhyA:
0.1
4k5fB-2xhyA:
undetectable		 4k5fA-2xhyA:
20.63
4k5fB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4k5gA-2xhyA:
undetectable
4k5gB-2xhyA:
undetectable		 4k5gA-2xhyA:
20.63
4k5gB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 4k5gA-2xhyA:
undetectable
4k5gB-2xhyA:
undetectable		 4k5gA-2xhyA:
20.63
4k5gB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4kchA-2xhyA:
undetectable
4kchB-2xhyA:
0.2		 4kchA-2xhyA:
20.63
4kchB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 4kcjA-2xhyA:
0.2
4kcjB-2xhyA:
undetectable		 4kcjA-2xhyA:
20.63
4kcjB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 4kcjA-2xhyA:
0.2
4kcjB-2xhyA:
undetectable		 4kcjA-2xhyA:
20.63
4kcjB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4kclA-2xhyA:
undetectable
4kclB-2xhyA:
undetectable		 4kclA-2xhyA:
20.63
4kclB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 4kcmA-2xhyA:
undetectable
4kcmB-2xhyA:
undetectable		 4kcmA-2xhyA:
20.63
4kcmB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4kcnA-2xhyA:
undetectable
4kcnB-2xhyA:
0.0		 4kcnA-2xhyA:
20.63
4kcnB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4kcoA-2xhyA:
undetectable
4kcoB-2xhyA:
undetectable		 4kcoA-2xhyA:
20.63
4kcoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 4luxA-2xhyA:
undetectable
4luxB-2xhyA:
undetectable		 4luxA-2xhyA:
20.63
4luxB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 4luxA-2xhyA:
undetectable
4luxB-2xhyA:
undetectable		 4luxA-2xhyA:
20.63
4luxB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWD_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 8 PRO A 246
VAL A 417
TYR A 360
LEU A 365
 None
 1.01A 4pwdA-2xhyA:
1.9		 4pwdA-2xhyA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 4uchA-2xhyA:
undetectable
4uchB-2xhyA:
undetectable		 4uchA-2xhyA:
21.03
4uchB-2xhyA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 8 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.42A 4uchA-2xhyA:
undetectable
4uchB-2xhyA:
undetectable		 4uchA-2xhyA:
21.03
4uchB-2xhyA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4ugzA-2xhyA:
undetectable
4ugzB-2xhyA:
undetectable		 4ugzA-2xhyA:
20.63
4ugzB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4uh1A-2xhyA:
undetectable
4uh1B-2xhyA:
0.0		 4uh1A-2xhyA:
20.63
4uh1B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 4uh1A-2xhyA:
undetectable
4uh1B-2xhyA:
0.0		 4uh1A-2xhyA:
20.63
4uh1B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 4uh2A-2xhyA:
undetectable
4uh2B-2xhyA:
undetectable		 4uh2A-2xhyA:
20.63
4uh2B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4uh3A-2xhyA:
0.1
4uh3B-2xhyA:
0.3		 4uh3A-2xhyA:
20.63
4uh3B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4uh4A-2xhyA:
undetectable
4uh4B-2xhyA:
0.0		 4uh4A-2xhyA:
20.63
4uh4B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 4uh4A-2xhyA:
undetectable
4uh4B-2xhyA:
0.0		 4uh4A-2xhyA:
20.63
4uh4B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4uh5A-2xhyA:
0.3
4uh5B-2xhyA:
undetectable		 4uh5A-2xhyA:
20.68
4uh5B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4uh5A-2xhyA:
0.3
4uh5B-2xhyA:
undetectable		 4uh5A-2xhyA:
20.68
4uh5B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4uh6A-2xhyA:
undetectable
4uh6B-2xhyA:
undetectable		 4uh6A-2xhyA:
20.68
4uh6B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4upmA-2xhyA:
undetectable
4upmB-2xhyA:
0.2		 4upmA-2xhyA:
20.63
4upmB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 4upmA-2xhyA:
undetectable
4upmB-2xhyA:
0.1		 4upmA-2xhyA:
20.63
4upmB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4upnA-2xhyA:
undetectable
4upnB-2xhyA:
undetectable		 4upnA-2xhyA:
20.63
4upnB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4upoA-2xhyA:
undetectable
4upoB-2xhyA:
undetectable		 4upoA-2xhyA:
20.63
4upoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 4uppA-2xhyA:
undetectable
4uppB-2xhyA:
undetectable		 4uppA-2xhyA:
20.63
4uppB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 4uppA-2xhyA:
undetectable
4uppB-2xhyA:
undetectable		 4uppA-2xhyA:
20.63
4uppB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4v3uA-2xhyA:
0.2
4v3uB-2xhyA:
undetectable		 4v3uA-2xhyA:
20.87
4v3uB-2xhyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.45A 4v3uC-2xhyA:
0.3
4v3uD-2xhyA:
undetectable		 4v3uC-2xhyA:
20.87
4v3uD-2xhyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 4v3uC-2xhyA:
0.3
4v3uD-2xhyA:
undetectable		 4v3uC-2xhyA:
20.87
4v3uD-2xhyA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 4v3vA-2xhyA:
0.3
4v3vB-2xhyA:
undetectable		 4v3vA-2xhyA:
20.63
4v3vB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 4v3xA-2xhyA:
undetectable
4v3xB-2xhyA:
undetectable		 4v3xA-2xhyA:
20.63
4v3xB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 4v3xA-2xhyA:
undetectable
4v3xB-2xhyA:
undetectable		 4v3xA-2xhyA:
20.63
4v3xB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 4v3yA-2xhyA:
undetectable
4v3yB-2xhyA:
undetectable		 4v3yA-2xhyA:
20.63
4v3yB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 4v3zA-2xhyA:
undetectable
4v3zB-2xhyA:
undetectable		 4v3zA-2xhyA:
20.63
4v3zB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 4v3zA-2xhyA:
undetectable
4v3zB-2xhyA:
undetectable		 4v3zA-2xhyA:
20.63
4v3zB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADB_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 5adbA-2xhyA:
undetectable
5adbB-2xhyA:
undetectable		 5adbA-2xhyA:
20.63
5adbB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5adcA-2xhyA:
0.2
5adcB-2xhyA:
undetectable		 5adcA-2xhyA:
20.63
5adcB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 5adcA-2xhyA:
0.2
5adcB-2xhyA:
undetectable		 5adcA-2xhyA:
20.63
5adcB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 5adfA-2xhyA:
0.3
5adfB-2xhyA:
undetectable		 5adfA-2xhyA:
20.68
5adfB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 5adgA-2xhyA:
0.0
5adgB-2xhyA:
undetectable		 5adgA-2xhyA:
20.68
5adgB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5agkA-2xhyA:
undetectable
5agkB-2xhyA:
undetectable		 5agkA-2xhyA:
20.63
5agkB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.44A 5agkA-2xhyA:
undetectable
5agkB-2xhyA:
undetectable		 5agkA-2xhyA:
20.63
5agkB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5aglA-2xhyA:
undetectable
5aglB-2xhyA:
undetectable		 5aglA-2xhyA:
20.63
5aglB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 5aglA-2xhyA:
undetectable
5aglB-2xhyA:
undetectable		 5aglA-2xhyA:
20.63
5aglB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5agmA-2xhyA:
undetectable
5agmB-2xhyA:
undetectable		 5agmA-2xhyA:
20.63
5agmB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 5agmA-2xhyA:
undetectable
5agmB-2xhyA:
0.1		 5agmA-2xhyA:
20.63
5agmB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5agnA-2xhyA:
undetectable
5agnB-2xhyA:
undetectable		 5agnA-2xhyA:
20.63
5agnB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 5agnA-2xhyA:
undetectable
5agnB-2xhyA:
undetectable		 5agnA-2xhyA:
20.63
5agnB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5agoA-2xhyA:
undetectable
5agoB-2xhyA:
0.1		 5agoA-2xhyA:
20.63
5agoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 5agoA-2xhyA:
undetectable
5agoB-2xhyA:
0.1		 5agoA-2xhyA:
20.63
5agoB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 5agpA-2xhyA:
undetectable
5agpB-2xhyA:
undetectable		 5agpA-2xhyA:
20.63
5agpB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.38A 5b1aG-2xhyA:
0.0
5b1aN-2xhyA:
0.0
5b1aO-2xhyA:
0.0		 5b1aG-2xhyA:
10.37
5b1aN-2xhyA:
20.62
5b1aO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.42A 5b1bG-2xhyA:
0.0
5b1bN-2xhyA:
0.1
5b1bO-2xhyA:
0.0		 5b1bG-2xhyA:
10.37
5b1bN-2xhyA:
20.62
5b1bO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5fvqA-2xhyA:
undetectable
5fvqB-2xhyA:
0.1		 5fvqA-2xhyA:
20.63
5fvqB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 5fvqA-2xhyA:
undetectable
5fvqB-2xhyA:
0.1		 5fvqA-2xhyA:
20.63
5fvqB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5fvrA-2xhyA:
undetectable
5fvrB-2xhyA:
undetectable		 5fvrA-2xhyA:
20.63
5fvrB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 5fvrA-2xhyA:
undetectable
5fvrB-2xhyA:
undetectable		 5fvrA-2xhyA:
20.63
5fvrB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5fvsA-2xhyA:
undetectable
5fvsB-2xhyA:
undetectable		 5fvsA-2xhyA:
20.63
5fvsB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 5fvtA-2xhyA:
undetectable
5fvtB-2xhyA:
undetectable		 5fvtA-2xhyA:
20.63
5fvtB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 5fvuA-2xhyA:
0.2
5fvuB-2xhyA:
undetectable		 5fvuA-2xhyA:
20.68
5fvuB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 5fvuA-2xhyA:
undetectable
5fvuB-2xhyA:
undetectable		 5fvuA-2xhyA:
20.68
5fvuB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 5fvvA-2xhyA:
0.3
5fvvB-2xhyA:
undetectable		 5fvvA-2xhyA:
20.68
5fvvB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5fvwA-2xhyA:
0.4
5fvwB-2xhyA:
0.0		 5fvwA-2xhyA:
20.68
5fvwB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 5fvwA-2xhyA:
0.4
5fvwB-2xhyA:
0.0		 5fvwA-2xhyA:
20.68
5fvwB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 5fw0A-2xhyA:
0.0
5fw0B-2xhyA:
undetectable		 5fw0A-2xhyA:
20.63
5fw0B-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 5g0nA-2xhyA:
undetectable
5g0nB-2xhyA:
undetectable		 5g0nA-2xhyA:
21.26
5g0nB-2xhyA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 5g0nA-2xhyA:
undetectable
5g0nB-2xhyA:
undetectable		 5g0nA-2xhyA:
21.26
5g0nB-2xhyA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 5g0oA-2xhyA:
0.3
5g0oB-2xhyA:
undetectable		 5g0oA-2xhyA:
21.26
5g0oB-2xhyA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_G_CHDG102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.37A 5iy5G-2xhyA:
0.0
5iy5N-2xhyA:
0.0
5iy5O-2xhyA:
0.0		 5iy5G-2xhyA:
10.39
5iy5N-2xhyA:
20.62
5iy5O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_T_CHDT103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.37A 5iy5A-2xhyA:
0.0
5iy5B-2xhyA:
0.0
5iy5T-2xhyA:
0.0		 5iy5A-2xhyA:
20.62
5iy5B-2xhyA:
18.60
5iy5T-2xhyA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ASP A 256
PHE A 259
GLY A 337
GLY A 326
 None
 0.95A 5n9xA-2xhyA:
undetectable		 5n9xA-2xhyA:
22.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5unsA-2xhyA:
undetectable
5unsB-2xhyA:
undetectable		 5unsA-2xhyA:
20.63
5unsB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5untA-2xhyA:
0.3
5untB-2xhyA:
0.0		 5untA-2xhyA:
20.63
5untB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 5uo4A-2xhyA:
undetectable
5uo4B-2xhyA:
undetectable		 5uo4A-2xhyA:
20.68
5uo4B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 5uo4A-2xhyA:
undetectable
5uo4B-2xhyA:
undetectable		 5uo4A-2xhyA:
20.68
5uo4B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 5uo5A-2xhyA:
0.1
5uo5B-2xhyA:
undetectable		 5uo5A-2xhyA:
20.68
5uo5B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 5uo5A-2xhyA:
0.3
5uo5B-2xhyA:
undetectable		 5uo5A-2xhyA:
20.68
5uo5B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 5uo6A-2xhyA:
0.2
5uo6B-2xhyA:
undetectable		 5uo6A-2xhyA:
20.68
5uo6B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 5uo7A-2xhyA:
undetectable
5uo7B-2xhyA:
0.4		 5uo7A-2xhyA:
20.68
5uo7B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 5vuiA-2xhyA:
undetectable
5vuiB-2xhyA:
0.0		 5vuiA-2xhyA:
20.63
5vuiB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5vulA-2xhyA:
0.0
5vulB-2xhyA:
undetectable		 5vulA-2xhyA:
20.63
5vulB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 5vulA-2xhyA:
0.0
5vulB-2xhyA:
undetectable		 5vulA-2xhyA:
20.63
5vulB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5vumA-2xhyA:
0.3
5vumB-2xhyA:
undetectable		 5vumA-2xhyA:
20.63
5vumB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 5vumA-2xhyA:
0.3
5vumB-2xhyA:
undetectable		 5vumA-2xhyA:
20.63
5vumB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 5vunA-2xhyA:
undetectable
5vunB-2xhyA:
undetectable		 5vunA-2xhyA:
20.63
5vunB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 5vunA-2xhyA:
undetectable
5vunB-2xhyA:
undetectable		 5vunA-2xhyA:
20.63
5vunB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 5vupA-2xhyA:
undetectable
5vupB-2xhyA:
undetectable		 5vupA-2xhyA:
20.63
5vupB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 5vupA-2xhyA:
undetectable
5vupB-2xhyA:
undetectable		 5vupA-2xhyA:
20.63
5vupB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5vuqA-2xhyA:
undetectable
5vuqB-2xhyA:
undetectable		 5vuqA-2xhyA:
20.63
5vuqB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.45A 5vurA-2xhyA:
undetectable
5vurB-2xhyA:
undetectable		 5vurA-2xhyA:
20.63
5vurB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5vusA-2xhyA:
0.3
5vusB-2xhyA:
0.0		 5vusA-2xhyA:
20.63
5vusB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5vutA-2xhyA:
undetectable
5vutB-2xhyA:
undetectable		 5vutA-2xhyA:
20.63
5vutB-2xhyA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5vuvA-2xhyA:
undetectable
5vuvB-2xhyA:
0.0		 5vuvA-2xhyA:
20.68
5vuvB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 5vuvA-2xhyA:
undetectable
5vuvB-2xhyA:
0.1		 5vuvA-2xhyA:
20.68
5vuvB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5vuwA-2xhyA:
0.0
5vuwB-2xhyA:
undetectable		 5vuwA-2xhyA:
20.68
5vuwB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 5vuwA-2xhyA:
0.0
5vuwB-2xhyA:
undetectable		 5vuwA-2xhyA:
20.68
5vuwB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5vuxA-2xhyA:
0.3
5vuxB-2xhyA:
0.0		 5vuxA-2xhyA:
20.68
5vuxB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5vuyA-2xhyA:
undetectable
5vuyB-2xhyA:
undetectable		 5vuyA-2xhyA:
20.68
5vuyB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.42A 5vuyA-2xhyA:
undetectable
5vuyB-2xhyA:
undetectable		 5vuyA-2xhyA:
20.68
5vuyB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 5vuzA-2xhyA:
undetectable
5vuzB-2xhyA:
undetectable		 5vuzA-2xhyA:
20.68
5vuzB-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 5vv0A-2xhyA:
undetectable
5vv0B-2xhyA:
undetectable		 5vv0A-2xhyA:
20.68
5vv0B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 5vv0A-2xhyA:
undetectable
5vv0B-2xhyA:
undetectable		 5vv0A-2xhyA:
20.68
5vv0B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5vv1A-2xhyA:
undetectable
5vv1B-2xhyA:
0.2		 5vv1A-2xhyA:
20.68
5vv1B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 6 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 5vv1A-2xhyA:
undetectable
5vv1B-2xhyA:
0.2		 5vv1A-2xhyA:
20.68
5vv1B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 5vv2A-2xhyA:
0.2
5vv2B-2xhyA:
undetectable		 5vv2A-2xhyA:
20.68
5vv2B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 5vv2A-2xhyA:
0.2
5vv2B-2xhyA:
undetectable		 5vv2A-2xhyA:
20.68
5vv2B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 5vv3A-2xhyA:
undetectable
5vv3B-2xhyA:
undetectable		 5vv3A-2xhyA:
20.68
5vv3B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 5vv3A-2xhyA:
undetectable
5vv3B-2xhyA:
undetectable		 5vv3A-2xhyA:
20.68
5vv3B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 5vv5A-2xhyA:
0.2
5vv5B-2xhyA:
undetectable		 5vv5A-2xhyA:
20.68
5vv5B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 5vv5A-2xhyA:
0.2
5vv5B-2xhyA:
undetectable		 5vv5A-2xhyA:
20.68
5vv5B-2xhyA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.38A 5w97G-2xhyA:
0.0
5w97a-2xhyA:
0.0
5w97b-2xhyA:
0.0		 5w97G-2xhyA:
10.37
5w97a-2xhyA:
20.62
5w97b-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.35A 5w97A-2xhyA:
0.0
5w97B-2xhyA:
0.0
5w97g-2xhyA:
0.0		 5w97A-2xhyA:
20.62
5w97B-2xhyA:
18.60
5w97g-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.39A 5wauA-2xhyA:
0.0
5wauB-2xhyA:
0.0
5waug-2xhyA:
0.0		 5wauA-2xhyA:
20.62
5wauB-2xhyA:
18.60
5waug-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_G_CHDG103_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.31A 5wauG-2xhyA:
0.0
5waua-2xhyA:
0.0
5waub-2xhyA:
0.0		 5wauG-2xhyA:
10.37
5waua-2xhyA:
20.62
5waub-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.36A 5x19A-2xhyA:
0.0
5x19B-2xhyA:
0.0
5x19T-2xhyA:
0.0		 5x19A-2xhyA:
20.62
5x19B-2xhyA:
18.60
5x19T-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.37A 5x19G-2xhyA:
0.0
5x19N-2xhyA:
0.0
5x19O-2xhyA:
0.0		 5x19G-2xhyA:
10.37
5x19N-2xhyA:
20.62
5x19O-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.28A 5x1bA-2xhyA:
0.0
5x1bB-2xhyA:
0.0
5x1bT-2xhyA:
0.0		 5x1bA-2xhyA:
20.62
5x1bB-2xhyA:
18.60
5x1bT-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_O_CHDO302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.37A 5x1bG-2xhyA:
0.0
5x1bN-2xhyA:
0.0
5x1bO-2xhyA:
0.0		 5x1bG-2xhyA:
10.37
5x1bN-2xhyA:
20.62
5x1bO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 10 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.33A 5x1fA-2xhyA:
0.0
5x1fB-2xhyA:
0.0
5x1fT-2xhyA:
0.0		 5x1fA-2xhyA:
20.62
5x1fB-2xhyA:
18.60
5x1fT-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_G_CHDG104_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 350
GLY A 381
TRP A 351
THR A 435
THR A 434
 None
None
None
None
SO4  A1481 (-4.0A)
 1.32A 5x1fG-2xhyA:
0.0
5x1fN-2xhyA:
0.0
5x1fO-2xhyA:
0.0		 5x1fG-2xhyA:
10.37
5x1fN-2xhyA:
20.62
5x1fO-2xhyA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 6aurA-2xhyA:
undetectable
6aurB-2xhyA:
0.1		 6aurA-2xhyA:
10.84
6aurB-2xhyA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 6autA-2xhyA:
undetectable
6autB-2xhyA:
undetectable		 6autA-2xhyA:
10.84
6autB-2xhyA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 6autA-2xhyA:
undetectable
6autB-2xhyA:
undetectable		 6autA-2xhyA:
10.84
6autB-2xhyA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.50A 6auuA-2xhyA:
0.2
6auuB-2xhyA:
undetectable		 6auuA-2xhyA:
10.84
6auuB-2xhyA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 6auvA-2xhyA:
undetectable
6auvB-2xhyA:
undetectable		 6auvA-2xhyA:
10.84
6auvB-2xhyA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 6auvA-2xhyA:
undetectable
6auvB-2xhyA:
undetectable		 6auvA-2xhyA:
10.84
6auvB-2xhyA:
10.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 6auyA-2xhyA:
0.3
6auyB-2xhyA:
undetectable		 6auyA-2xhyA:
11.06
6auyB-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.46A 6auyA-2xhyA:
0.2
6auyB-2xhyA:
undetectable		 6auyA-2xhyA:
11.06
6auyB-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 6auzA-2xhyA:
0.3
6auzB-2xhyA:
0.3		 6auzA-2xhyA:
11.06
6auzB-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 6av0A-2xhyA:
undetectable
6av0B-2xhyA:
undetectable		 6av0A-2xhyA:
11.06
6av0B-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.47A 6av1A-2xhyA:
undetectable
6av1B-2xhyA:
undetectable		 6av1A-2xhyA:
11.06
6av1B-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.48A 6av2A-2xhyA:
undetectable
6av2B-2xhyA:
undetectable		 6av2A-2xhyA:
11.06
6av2B-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.47A 6av3A-2xhyA:
0.2
6av3B-2xhyA:
undetectable		 6av3A-2xhyA:
11.06
6av3B-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 6av3A-2xhyA:
0.2
6av3B-2xhyA:
undetectable		 6av3A-2xhyA:
11.06
6av3B-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.46A 6av4A-2xhyA:
undetectable
6av4B-2xhyA:
undetectable		 6av4A-2xhyA:
11.06
6av4B-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.49A 6av4A-2xhyA:
undetectable
6av4B-2xhyA:
undetectable		 6av4A-2xhyA:
11.06
6av4B-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.50A 6cicA-2xhyA:
0.3
6cicB-2xhyA:
undetectable		 6cicA-2xhyA:
11.06
6cicB-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 PHE A  98
GLU A 108
ARG A 159
VAL A 164
 None
 1.48A 6cicA-2xhyA:
0.3
6cicB-2xhyA:
undetectable		 6cicA-2xhyA:
11.06
6cicB-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		4 / 7 ARG A 159
VAL A 164
PHE A  98
GLU A 108
 None
 1.49A 6cidA-2xhyA:
0.0
6cidB-2xhyA:
undetectable		 6cidA-2xhyA:
11.06
6cidB-2xhyA:
11.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_B_CHDB304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 381
TRP A 351
THR A 435
THR A 434
GLY A 350
 None
None
None
SO4  A1481 (-4.0A)
None
 1.37A 6nknA-2xhyA:
0.2
6nknB-2xhyA:
0.0
6nknT-2xhyA:
0.0		 6nknA-2xhyA:
20.62
6nknB-2xhyA:
18.60
6nknT-2xhyA:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		3 / 3 ARG A 459
PHE A 444
PHE A  69
 None
 1.07A 6nknC-2xhyA:
undetectable
6nknJ-2xhyA:
undetectable		 6nknC-2xhyA:
18.75
6nknJ-2xhyA:
8.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 239
LEU A 132
ALA A 225
ALA A 229
PHE A 165
 None
 1.42A 6qgbA-2xhyA:
undetectable		 6qgbA-2xhyA:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 2xhy 6-PHOSPHO-BETA-GLUCO
SIDASE BGLA
(Escherichia
coli) 		5 / 11 GLY A 239
LEU A 132
ALA A 225
ALA A 229
PHE A 165
 None
 1.44A 6qgbE-2xhyA:
undetectable		 6qgbE-2xhyA:
19.55