SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xhz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IDK_A_C2FA1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 11 THR A 113
LEU A 119
SER A 109
LEU A  91
MET A  93
 None
 1.48A 2idkA-2xhzA:
undetectable
2idkB-2xhzA:
undetectable
2idkC-2xhzA:
undetectable
2idkD-2xhzA:
undetectable		 2idkA-2xhzA:
22.60
2idkB-2xhzA:
22.60
2idkC-2xhzA:
22.60
2idkD-2xhzA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A  63
ILE A 103
GLY A 171
ALA A 177
VAL A 176
 None
 1.20A 2yvlC-2xhzA:
undetectable		 2yvlC-2xhzA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 PHE A  79
ILE A 129
ALA A 175
THR A  74
ALA A  69
 None
 1.29A 3ua1A-2xhzA:
undetectable		 3ua1A-2xhzA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RKU_A_PQNA5001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		4 / 8 MET A  67
PHE A  71
ALA A 177
LEU A 178
 None
 0.91A 4rkuA-2xhzA:
undetectable
4rkuJ-2xhzA:
undetectable		 4rkuA-2xhzA:
12.48
4rkuJ-2xhzA:
12.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		3 / 3 GLU A  23
ILE A  63
ALA A 159
 None
 0.66A 4wnwB-2xhzA:
undetectable		 4wnwB-2xhzA:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA844_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		4 / 7 MET A  67
PHE A  71
ALA A 177
LEU A 178
 None
 1.03A 4xk8A-2xhzA:
undetectable		 4xk8A-2xhzA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XK8_A_PQNA845_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		4 / 8 MET A  67
PHE A  71
ALA A 177
LEU A 178
 None
 1.01A 4xk8a-2xhzA:
undetectable		 4xk8a-2xhzA:
12.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		5 / 12 ILE A  63
GLY A  61
ASP A 172
SER A  73
PHE A  71
 None
 1.16A 5igwA-2xhzA:
undetectable		 5igwA-2xhzA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA806_0
(GEPHYRIN)		 2xhz ARABINOSE
5-PHOSPHATE
ISOMERASE
(Escherichia
coli) 		4 / 4 MET A  57
GLY A  58
HIS A  62
GLY A  56
 None
 1.12A 6fgdA-2xhzA:
3.3		 6fgdA-2xhzA:
19.19