SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xi8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LUH_A_ACTA610_0 (SERUM ALBUMIN)	2xi8	PUTATIVE TRANSCRIPTION REGULATOR (Enterococcus faecalis)	3 / 3	VAL A 26 SER A 27 THR A 30	None	0.39A	4luhA-2xi8A: undetectable	4luhA-2xi8A: 8.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YFB_C_PACC601_0 (PROTEIN RELATED TO PENICILLIN ACYLASE)	2xi8	PUTATIVE TRANSCRIPTION REGULATOR (Enterococcus faecalis)	5 / 12	SER A 42 PRO A 41 PHE A 61 ILE A 34 VAL A 26	GOL A1067 (-2.6A) None None None None	1.24A	4yfbC-2xi8A: undetectable	4yfbC-2xi8A: 8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YFB_F_PACF601_0 (PROTEIN RELATED TO PENICILLIN ACYLASE)	2xi8	PUTATIVE TRANSCRIPTION REGULATOR (Enterococcus faecalis)	5 / 12	SER A 42 PRO A 41 PHE A 61 ILE A 34 VAL A 26	GOL A1067 (-2.6A) None None None None	1.24A	4yfbF-2xi8A: undetectable	4yfbF-2xi8A: 8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YFB_I_PACI601_0 (PROTEIN RELATED TO PENICILLIN ACYLASE)	2xi8	PUTATIVE TRANSCRIPTION REGULATOR (Enterococcus faecalis)	5 / 12	SER A 42 PRO A 41 PHE A 61 ILE A 34 VAL A 26	GOL A1067 (-2.6A) None None None None	1.24A	4yfbI-2xi8A: undetectable	4yfbI-2xi8A: 8.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YFB_L_PACL601_0 (PROTEIN RELATED TO PENICILLIN ACYLASE)	2xi8	PUTATIVE TRANSCRIPTION REGULATOR (Enterococcus faecalis)	5 / 12	SER A 42 PRO A 41 PHE A 61 ILE A 34 VAL A 26	GOL A1067 (-2.6A) None None None None	1.24A	4yfbL-2xi8A: undetectable	4yfbL-2xi8A: 8.83

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4LUH_A_ACTA610_0","SERUM ALBUMIN","2xi8","PUTATIVE TRANSCRIPTION REGULATOR","Enterococcus faecalis",3,"VAL A  26;SER A  27;THR A  30","None","0.39A","4luhA-2xi8A:undetectable","4luhA-2xi8A:8.84"],["4YFB_C_PACC601_0","PROTEIN RELATED TO PENICILLIN ACYLASE","2xi8","PUTATIVE TRANSCRIPTION REGULATOR","Enterococcus faecalis",5,"SER A  42;PRO A  41;PHE A  61;ILE A  34;VAL A  26","GOL A1067 (-2.6A);None;None;None;None","1.24A","4yfbC-2xi8A:undetectable","4yfbC-2xi8A:8.83"],["4YFB_F_PACF601_0","PROTEIN RELATED TO PENICILLIN ACYLASE","2xi8","PUTATIVE TRANSCRIPTION REGULATOR","Enterococcus faecalis",5,"SER A  42;PRO A  41;PHE A  61;ILE A  34;VAL A  26","GOL A1067 (-2.6A);None;None;None;None","1.24A","4yfbF-2xi8A:undetectable","4yfbF-2xi8A:8.83"],["4YFB_I_PACI601_0","PROTEIN RELATED TO PENICILLIN ACYLASE","2xi8","PUTATIVE TRANSCRIPTION REGULATOR","Enterococcus faecalis",5,"SER A  42;PRO A  41;PHE A  61;ILE A  34;VAL A  26","GOL A1067 (-2.6A);None;None;None;None","1.24A","4yfbI-2xi8A:undetectable","4yfbI-2xi8A:8.83"],["4YFB_L_PACL601_0","PROTEIN RELATED TO PENICILLIN ACYLASE","2xi8","PUTATIVE TRANSCRIPTION REGULATOR","Enterococcus faecalis",5,"SER A  42;PRO A  41;PHE A  61;ILE A  34;VAL A  26","GOL A1067 (-2.6A);None;None;None;None","1.24A","4yfbL-2xi8A:undetectable","4yfbL-2xi8A:8.83"]]