SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xkk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PBC_A_BHAA396_0
(P-HYDROXYBENZOATE
HYDROXYLASE)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 10 GLY A1041
LEU A1136
TYR A1132
LEU A1103
TYR A1099
 None
 1.41A 1pbcA-2xkkA:
undetectable		 1pbcA-2xkkA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 4 THR A 553
GLY A 541
ASP A 467
ALA A 399
 None
None
MG  A2487 (-2.9A)
None
 1.03A 1sg9A-2xkkA:
2.4		 1sg9A-2xkkA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		3 / 3 THR A1361
GLU A1468
HIS A1369
 None
 0.85A 1xwfA-2xkkA:
undetectable		 1xwfA-2xkkA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		3 / 3 THR A1361
GLU A1468
HIS A1369
 None
 0.86A 1xwfB-2xkkA:
undetectable		 1xwfB-2xkkA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		3 / 3 THR A1361
GLU A1468
HIS A1369
 None
 0.84A 1xwfC-2xkkA:
undetectable		 1xwfC-2xkkA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		3 / 3 THR A1361
GLU A1468
HIS A1369
 None
 0.88A 1xwfD-2xkkA:
undetectable		 1xwfD-2xkkA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1M_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 7 THR A1227
VAL A1331
GLY A1241
THR A1238
 None
 0.91A 2a1mA-2xkkA:
undetectable		 2a1mA-2xkkA:
20.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BFP_A_H4BA1290_1
(PTERIDINE REDUCTASE
1)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 8 SER A1138
LEU A1469
LEU A1189
LEU A1170
 None
 1.01A 2bfpA-2xkkA:
undetectable		 2bfpA-2xkkA:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 4 SER A1154
GLY A1153
HIS A1079
ASP A 471
 None
 1.40A 2oxtC-2xkkA:
undetectable		 2oxtC-2xkkA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_H_TOPH200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 9 GLU A1468
LEU A1464
VAL A1362
ILE A1451
LEU A1455
 None
 1.23A 3fl9H-2xkkA:
undetectable		 3fl9H-2xkkA:
11.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 8 PHE A1320
THR A1299
VAL A1270
VAL A1265
 None
 0.76A 3me6B-2xkkA:
undetectable		 3me6B-2xkkA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PFG_A_SAMA264_0
(N-METHYLTRANSFERASE)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 12 ALA A1163
HIS A1037
LEU A1135
SER A1133
ASP A1472
 None
 1.19A 3pfgA-2xkkA:
undetectable		 3pfgA-2xkkA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 9 THR A1018
LEU A 572
LEU A 576
GLY A 575
VAL A 484
 None
 1.42A 4c9kB-2xkkA:
undetectable		 4c9kB-2xkkA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOE_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA4)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 7 GLY A 396
ASP A 397
GLY A 419
GLU A 437
 None
 0.69A 4koeA-2xkkA:
48.2
4koeB-2xkkA:
48.1
4koeD-2xkkA:
24.5		 4koeA-2xkkA:
27.59
4koeB-2xkkA:
27.59
4koeD-2xkkA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOU_A_C04A207_1
(UNCHARACTERIZED
PROTEIN)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		3 / 3 GLY A1106
GLU A1126
THR A1125
 None
None
PTR  A1124 ( 3.8A)
 0.53A 4kouA-2xkkA:
undetectable		 4kouA-2xkkA:
13.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNW_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 8 SER A1460
GLU A1459
VAL A1362
THR A1363
 None
 0.88A 4lnwA-2xkkA:
undetectable		 4lnwA-2xkkA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 6 SER A1460
GLU A1459
VAL A1362
THR A1363
 None
 0.99A 4lnxA-2xkkA:
undetectable		 4lnxA-2xkkA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 5 TYR A1243
THR A1196
LEU A1351
THR A1238
 None
 1.24A 4mbsB-2xkkA:
undetectable		 4mbsB-2xkkA:
19.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MX0_A_BCZA513_1
(NEURAMINIDASE)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		3 / 3 ARG A1358
ASP A1472
ARG A1365
 None
 0.97A 4mx0A-2xkkA:
undetectable		 4mx0A-2xkkA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OJB_A_198A1001_2
(ANDROGEN RECEPTOR)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 7 LEU A1325
ILE A1225
ILE A1226
VAL A1485
 None
 0.73A 4ojbA-2xkkA:
undetectable		 4ojbA-2xkkA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_F_TR6F101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 5 GLY A 396
ARG A 418
GLY A 419
GLU A 437
 None
 1.01A 4z2eB-2xkkA:
47.5
4z2eC-2xkkA:
22.2		 4z2eB-2xkkA:
29.95
4z2eC-2xkkA:
18.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 5 ARG A 418
GLY A 419
GLU A 437
SER A1084
 None
None
None
MG  A1504 ( 3.8A)
 0.98A 4z3oA-2xkkA:
22.5
4z3oB-2xkkA:
48.3		 4z3oA-2xkkA:
40.13
4z3oB-2xkkA:
40.13
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4Z53_H_TR6H101_1
(DNA TOPOISOMERASE 4
SUBUNIT B,DNA
TOPOISOMERASE 4
SUBUNIT A
E-SITE DNA)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 7 GLY A 396
ASP A 397
GLY A 419
GLU A 437
 None
 0.82A 4z53A-2xkkA:
48.4
4z53B-2xkkA:
48.4		 4z53A-2xkkA:
40.13
4z53B-2xkkA:
40.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2S_A_ACTA107_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		3 / 3 VAL A1257
THR A1259
ARG A1300
 None
 0.61A 5b2sB-2xkkA:
undetectable		 5b2sB-2xkkA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2T_A_ACTA108_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9
GUIDE RNA)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		3 / 3 VAL A1257
THR A1259
ARG A1300
 None
 0.55A 5b2tB-2xkkA:
0.4		 5b2tB-2xkkA:
21.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 7 ASP A 397
ARG A 418
GLY A 419
GLU A 437
 None
 0.71A 5bs8A-2xkkA:
48.2
5bs8C-2xkkA:
48.2
5bs8D-2xkkA:
26.5		 5bs8A-2xkkA:
30.59
5bs8C-2xkkA:
30.59
5bs8D-2xkkA:
20.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 7 SER A1084
ASP A 397
ARG A 418
GLY A 419
GLU A 437
 MG  A1504 ( 3.8A)
None
None
None
None
 0.75A 5btaA-2xkkA:
48.2
5btaC-2xkkA:
48.3
5btaD-2xkkA:
26.4		 5btaA-2xkkA:
30.73
5btaC-2xkkA:
30.73
5btaD-2xkkA:
20.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BTA_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 6 SER A1084
ARG A 418
GLY A 419
GLU A 437
 MG  A1504 ( 3.8A)
None
None
None
 0.68A 5btaA-2xkkA:
48.2
5btaB-2xkkA:
26.4
5btaC-2xkkA:
48.3		 5btaA-2xkkA:
30.73
5btaB-2xkkA:
20.79
5btaC-2xkkA:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 6 SER A1084
ARG A 418
GLY A 419
GLU A 437
 MG  A1504 ( 3.8A)
None
None
None
 0.67A 5btcA-2xkkA:
48.1
5btcC-2xkkA:
48.0
5btcD-2xkkA:
26.4		 5btcA-2xkkA:
30.73
5btcC-2xkkA:
30.73
5btcD-2xkkA:
20.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 6 SER A1084
ARG A 418
GLY A 419
GLU A 437
 MG  A1504 ( 3.8A)
None
None
None
 0.72A 5btcA-2xkkA:
48.1
5btcB-2xkkA:
26.3
5btcC-2xkkA:
48.0		 5btcA-2xkkA:
30.73
5btcB-2xkkA:
20.79
5btcC-2xkkA:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 7 ASP A 397
ARG A 418
GLY A 419
GLU A 437
 None
 0.68A 5btdA-2xkkA:
48.1
5btdC-2xkkA:
48.2
5btdD-2xkkA:
26.3		 5btdA-2xkkA:
30.59
5btdC-2xkkA:
30.59
5btdD-2xkkA:
20.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 7 SER A1084
ASP A 397
ARG A 418
GLY A 419
GLU A 437
 MG  A1504 ( 3.8A)
None
None
None
None
 0.70A 5btfA-2xkkA:
48.0
5btfB-2xkkA:
26.4
5btfC-2xkkA:
48.1		 5btfA-2xkkA:
30.73
5btfB-2xkkA:
20.79
5btfC-2xkkA:
30.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 7 ASP A 397
ARG A 418
GLY A 419
GLU A 437
 None
 0.61A 5btfA-2xkkA:
48.0
5btfC-2xkkA:
48.1
5btfD-2xkkA:
26.3		 5btfA-2xkkA:
30.73
5btfC-2xkkA:
30.73
5btfD-2xkkA:
20.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 7 ASP A 397
ARG A 418
GLY A 419
GLU A 437
 None
 0.76A 5btgA-2xkkA:
48.1
5btgC-2xkkA:
48.1
5btgD-2xkkA:
26.2		 5btgA-2xkkA:
30.59
5btgC-2xkkA:
30.59
5btgD-2xkkA:
20.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 5 SER A1084
ARG A 418
GLY A 419
GLU A 437
 MG  A1504 ( 3.8A)
None
None
None
 0.83A 5btiC-2xkkA:
48.2
5btiD-2xkkA:
26.4		 5btiC-2xkkA:
30.73
5btiD-2xkkA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 6 GLY A 396
ASP A 397
ARG A 418
GLY A 419
 None
 0.80A 5cdnR-2xkkA:
48.7
5cdnS-2xkkA:
23.0		 5cdnR-2xkkA:
29.33
5cdnS-2xkkA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 6 SER A1084
GLY A 396
ASP A 397
GLY A 419
 MG  A1504 ( 3.8A)
None
None
None
 0.56A 5cdnT-2xkkA:
49.4
5cdnU-2xkkA:
23.0		 5cdnT-2xkkA:
29.33
5cdnU-2xkkA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 6 SER A1084
GLU A1088
GLY A 396
ASP A 397
GLY A 419
 MG  A1504 ( 3.8A)
MG  A1504 ( 4.7A)
None
None
None
 0.68A 5cdpA-2xkkA:
49.0
5cdpB-2xkkA:
23.1		 5cdpA-2xkkA:
29.96
5cdpB-2xkkA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 5 SER A1084
ARG A 418
GLY A 419
GLU A 437
 MG  A1504 ( 3.8A)
None
None
None
 0.99A 5cdqA-2xkkA:
48.9
5cdqB-2xkkA:
23.8
5cdqC-2xkkA:
49.0		 5cdqA-2xkkA:
29.33
5cdqB-2xkkA:
17.64
5cdqC-2xkkA:
29.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 5 SER A1084
ARG A 418
GLY A 419
GLU A 437
 MG  A1504 ( 3.8A)
None
None
None
 0.98A 5cdqR-2xkkA:
49.0
5cdqS-2xkkA:
23.5
5cdqT-2xkkA:
49.6		 5cdqR-2xkkA:
29.33
5cdqS-2xkkA:
17.64
5cdqT-2xkkA:
29.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_3_BEZ3801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 4 LEU A1199
ILE A1200
GLY A1195
ILE A1466
 None
 0.77A 5dzk3-2xkkA:
undetectable
5dzkm-2xkkA:
undetectable		 5dzk3-2xkkA:
1.49
5dzkm-2xkkA:
14.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 5 ILE A1200
GLY A1195
ILE A1466
LEU A1199
 None
 0.79A 5dzkB-2xkkA:
undetectable
5dzkI-2xkkA:
undetectable
5dzkW-2xkkA:
undetectable		 5dzkB-2xkkA:
17.06
5dzkI-2xkkA:
14.91
5dzkW-2xkkA:
1.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 5 ILE A1200
GLY A1195
ILE A1466
LEU A1199
 None
 0.77A 5dzki-2xkkA:
undetectable
5dzkj-2xkkA:
undetectable
5dzkx-2xkkA:
undetectable		 5dzki-2xkkA:
14.91
5dzkj-2xkkA:
14.91
5dzkx-2xkkA:
1.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 5 ILE A1200
GLY A1195
ILE A1466
LEU A1199
 None
 0.80A 5dzkd-2xkkA:
undetectable
5dzkk-2xkkA:
undetectable
5dzky-2xkkA:
undetectable		 5dzkd-2xkkA:
17.06
5dzkk-2xkkA:
14.91
5dzky-2xkkA:
1.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 4 ILE A1200
GLY A1195
ILE A1466
LEU A1199
 None
 0.81A 5dzkl-2xkkA:
undetectable
5dzkz-2xkkA:
undetectable		 5dzkl-2xkkA:
14.91
5dzkz-2xkkA:
1.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ENT_C_MIYC901_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT
ACRB,MULTIDRUG
EFFLUX PUMP SUBUNIT
ACRB)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 9 GLN A 591
GLY A1179
ASN A1334
ILE A1030
ALA A1026
 None
 1.40A 5entC-2xkkA:
4.5		 5entC-2xkkA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_A_PFLA412_1
(PROTON-GATED ION
CHANNEL)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 10 PRO A1217
TYR A1243
ILE A1235
VAL A1331
ILE A1347
 None
 1.34A 5mzrA-2xkkA:
undetectable		 5mzrA-2xkkA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_C_PFLC409_1
(PROTON-GATED ION
CHANNEL)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 10 PRO A1217
TYR A1243
ILE A1235
VAL A1331
ILE A1347
 None
 1.33A 5mzrC-2xkkA:
1.4		 5mzrC-2xkkA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MZR_D_PFLD410_1
(PROTON-GATED ION
CHANNEL)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 9 PRO A1217
TYR A1243
ILE A1235
VAL A1331
ILE A1347
 None
 1.30A 5mzrD-2xkkA:
undetectable		 5mzrD-2xkkA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUN_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		5 / 9 ALA A 476
ILE A 462
LEU A 496
ILE A 441
ALA A 466
 None
 0.93A 5nunA-2xkkA:
undetectable		 5nunA-2xkkA:
8.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 2xkk TOPOISOMERASE IV
(Acinetobacter
baumannii) 		4 / 8 TYR A1028
GLN A1148
PRO A1044
GLU A1157
 None
 1.02A 6hzpA-2xkkA:
2.1		 6hzpA-2xkkA:
20.46