SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xn1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 12 SER A 184
LEU A 123
GLY A 278
TYR A 512
SER A 258
 None
 1.31A 1fdsA-2xn1A:
undetectable		 1fdsA-2xn1A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 4 LEU A 123
GLY A 259
ASP A 538
TYR A 512
 None
 1.47A 1oxrA-2xn1A:
undetectable		 1oxrA-2xn1A:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SV9_A_DIFA701_1
(PHOSPHOLIPASE A2)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 8 LEU A 515
ILE A 479
CYH A 530
GLY A 529
 None
None
TRS  A1733 (-3.2A)
None
 0.82A 1sv9A-2xn1A:
undetectable		 1sv9A-2xn1A:
10.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 10 HIS A 316
ALA A 254
LEU A 199
GLY A 535
PHE A 537
 None
 1.02A 1uhoA-2xn1A:
undetectable		 1uhoA-2xn1A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_B_THRB402_0
(ASPARTOKINASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 9 ASN A 233
ILE A 562
GLY A 534
GLU A 206
ALA A 550
 None
 1.27A 2dtjA-2xn1A:
undetectable
2dtjB-2xn1A:
undetectable		 2dtjA-2xn1A:
14.07
2dtjB-2xn1A:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ITZ_A_IREA2021_2
(EPIDERMAL GROWTH
FACTOR RECEPTOR)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 3 LEU A 515
LEU A 452
MET A 420
 None
 0.49A 2itzA-2xn1A:
undetectable		 2itzA-2xn1A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 7 LEU A 369
LEU A 414
PHE A 412
LEU A 352
GLU A 349
 None
 1.02A 2vq5B-2xn1A:
undetectable		 2vq5B-2xn1A:
14.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_D_QPSD1050_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 12 GLN A 449
ASN A 338
ASP A 370
ASP A 482
HIS A 203
 None
None
TRS  A1733 (-2.7A)
TRS  A1733 (-3.2A)
GOL  A1734 ( 4.4A)
 1.19A 2x2iD-2xn1A:
17.3		 2x2iD-2xn1A:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 6 ARG A  96
PRO A  64
GLY A  84
MET A  86
 None
None
GOL  A1738 (-2.7A)
GOL  A1738 (-4.6A)
 1.47A 3aqiA-2xn1A:
undetectable		 3aqiA-2xn1A:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFQ_B_DIFB1_1
(TRANSTHYRETIN)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 7 SER A 473
LEU A 369
ALA A 402
LEU A 414
 None
 0.96A 3cfqA-2xn1A:
undetectable
3cfqB-2xn1A:
undetectable		 3cfqA-2xn1A:
10.32
3cfqB-2xn1A:
10.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 3 ASN A 260
ASP A 538
GLN A 541
 None
 0.44A 3eeyC-2xn1A:
undetectable		 3eeyC-2xn1A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 3 ASN A 260
ASP A 538
GLN A 541
 None
 0.46A 3eeyD-2xn1A:
undetectable		 3eeyD-2xn1A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 3 ASN A 260
ASP A 538
GLN A 541
 None
 0.44A 3eeyE-2xn1A:
undetectable		 3eeyE-2xn1A:
13.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 7 GLY A 413
HIS A 406
ASP A 477
ILE A 525
 None
 0.90A 3fi0P-2xn1A:
undetectable		 3fi0P-2xn1A:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_A_ROFA901_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 3 ASP A  56
LEU A  55
GLN A 272
 None
 0.83A 3g4lA-2xn1A:
undetectable		 3g4lA-2xn1A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 12 GLU A 608
GLY A 372
ASP A 552
ASP A 380
GLY A 532
 None
None
TRS  A1733 (-2.8A)
None
GOL  A1734 ( 3.3A)
 1.29A 3jzjA-2xn1A:
undetectable		 3jzjA-2xn1A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 12 GLY A  40
GLY A  41
VAL A 190
ASP A 191
PRO A  77
 None
 1.11A 3m6vA-2xn1A:
undetectable		 3m6vA-2xn1A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 12 GLY A  40
GLY A  41
VAL A 190
ASP A 191
PRO A  77
 None
 1.06A 3m6wA-2xn1A:
undetectable		 3m6wA-2xn1A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RAE_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 4 SER A 486
GLY A 201
GLU A 558
 None
 0.65A 3raeA-2xn1A:
undetectable
3raeC-2xn1A:
undetectable		 3raeA-2xn1A:
22.37
3raeC-2xn1A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA91_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 3 PHE A 284
GLN A 500
PHE A 294
 None
 0.79A 3rv5A-2xn1A:
undetectable		 3rv5A-2xn1A:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DJE_A_C2FA300_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 12 ASP A 370
GLY A 533
SER A 531
GLN A 541
ARG A 536
 TRS  A1733 (-2.7A)
TRS  A1733 (-4.4A)
None
None
None
 1.37A 4djeA-2xn1A:
8.5		 4djeA-2xn1A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKJ_A_SUZA201_1
(TRANSTHYRETIN)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 7 LEU A 369
ALA A 402
LEU A 414
SER A 473
 None
 0.95A 4ikjA-2xn1A:
undetectable
4ikjB-2xn1A:
undetectable		 4ikjA-2xn1A:
11.35
4ikjB-2xn1A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_A_SUZA201_1
(TRANSTHYRETIN)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 8 LEU A 369
ALA A 402
LEU A 414
SER A 473
 None
 0.97A 4ikkA-2xn1A:
undetectable
4ikkB-2xn1A:
undetectable		 4ikkA-2xn1A:
11.35
4ikkB-2xn1A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKK_B_SUZB201_1
(TRANSTHYRETIN)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 7 SER A 473
LEU A 369
ALA A 402
LEU A 414
 None
 0.97A 4ikkA-2xn1A:
undetectable
4ikkB-2xn1A:
undetectable		 4ikkA-2xn1A:
11.35
4ikkB-2xn1A:
11.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JUO_F_LFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B
E-SITE DNA)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 4 SER A 486
GLY A 201
GLU A 558
 None
 0.61A 4juoA-2xn1A:
undetectable
4juoC-2xn1A:
undetectable		 4juoA-2xn1A:
22.37
4juoC-2xn1A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 8 LEU A 644
SER A 567
VAL A 635
GLY A 639
 None
 1.00A 4klrB-2xn1A:
undetectable		 4klrB-2xn1A:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MS4_A_2C0A501_1
(GAMMA-AMINOBUTYRIC
ACID TYPE B RECEPTOR
SUBUNIT 1)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 8 SER A 228
TYR A 570
ILE A 548
GLU A 206
 None
 1.11A 4ms4A-2xn1A:
undetectable		 4ms4A-2xn1A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 7 TYR A 570
ALA A 550
GLY A 533
GLY A 529
 None
None
TRS  A1733 (-4.4A)
None
 0.83A 5e26A-2xn1A:
undetectable
5e26B-2xn1A:
undetectable		 5e26A-2xn1A:
20.05
5e26B-2xn1A:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 11 GLN A 168
VAL A 139
THR A 136
TYR A 108
LEU A 141
 None
None
None
None
GOL  A1736 ( 3.3A)
 1.34A 5jh7B-2xn1A:
undetectable		 5jh7B-2xn1A:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_A_ACTA703_0
(HETERODISULFIDE
REDUCTASE, SUBUNIT A)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 6 ARG A 333
ARG A 633
PHE A 638
GLU A 634
 None
 1.42A 5odqA-2xn1A:
undetectable		 5odqA-2xn1A:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCV_A_1N1A404_2
(MEMBRANE-ASSOCIATED
TYROSINE- AND
THREONINE-SPECIFIC
CDC2-INHIBITORY
KINASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 5 VAL A 508
HIS A 261
LEU A 487
ASP A 538
 None
 1.00A 5vcvA-2xn1A:
undetectable		 5vcvA-2xn1A:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 6 TYR A  38
GLU A  79
TYR A  24
GLY A  41
 None
 0.94A 5x7pB-2xn1A:
undetectable		 5x7pB-2xn1A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YBB_B_SAMB601_1
(TYPE I
RESTRICTION-MODIFICA
TION SYSTEM
METHYLTRANSFERASE
SUBUNIT)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 7 ALA A 550
GLY A 533
GLU A 206
THR A 566
 None
TRS  A1733 (-4.4A)
None
None
 0.78A 5ybbB-2xn1A:
undetectable		 5ybbB-2xn1A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA608_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 3 GLY A 116
THR A 136
GLU A 114
 None
 0.61A 6b58A-2xn1A:
undetectable		 6b58A-2xn1A:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 12 HIS A 203
ARG A 377
GLY A 372
GLY A 532
GLY A 533
 GOL  A1734 ( 4.4A)
None
None
GOL  A1734 ( 3.3A)
TRS  A1733 (-4.4A)
 1.17A 6brdB-2xn1A:
undetectable		 6brdB-2xn1A:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		5 / 12 PHE A 464
LEU A 452
VAL A 519
ARG A 460
ASP A 513
 None
 1.24A 6bxnA-2xn1A:
undetectable		 6bxnA-2xn1A:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 8 PRO A 234
ILE A 548
THR A 545
TYR A 544
 None
 0.97A 6cduG-2xn1A:
undetectable
6cduH-2xn1A:
undetectable		 6cduG-2xn1A:
18.38
6cduH-2xn1A:
18.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 7 SER A 228
GLY A 540
VAL A 519
LEU A 515
 None
 0.70A 6dwnB-2xn1A:
undetectable		 6dwnB-2xn1A:
7.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 6 PHE A 347
VAL A 389
LEU A 414
LEU A 369
 None
 0.97A 6e43A-2xn1A:
undetectable		 6e43A-2xn1A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 6 PHE A 347
VAL A 389
LEU A 414
LEU A 369
 None
 0.96A 6e43C-2xn1A:
undetectable		 6e43C-2xn1A:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 3 LEU A  50
GLN A  49
LYS A 192
 None
 0.77A 6exiB-2xn1A:
undetectable		 6exiB-2xn1A:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		3 / 3 LEU A  50
GLN A  49
LYS A 192
 None
 0.75A 6exiA-2xn1A:
undetectable		 6exiA-2xn1A:
8.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_1
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 5 GLU A 717
ASP A 714
ASN A 594
TYR A 726
 None
None
None
GOL  A1737 ( 4.3A)
 0.96A 6iftA-2xn1A:
undetectable		 6iftA-2xn1A:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_F_AM2F301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 2xn1 ALPHA-GALACTOSIDASE
(Lactobacillus
acidophilus) 		4 / 7 ARG A 377
HIS A 376
ASP A 371
GLU A 417
 None
 1.41A 6mn4F-2xn1A:
undetectable		 6mn4F-2xn1A:
16.80