SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xnd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_B_SUEB1202_1
(NS3 PROTEASE)		 2xnd ATP SYNTHASE SUBUNIT
DELTA, MITOCHONDRIAL
(Bos
taurus) 		5 / 9 VAL H  36
HIS H  66
LEU H  93
ALA H  21
VAL H  26
 None
 1.14A 6c2mB-2xndH:
undetectable		 6c2mB-2xndH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_1
(NS3 PROTEASE)		 2xnd ATP SYNTHASE SUBUNIT
DELTA, MITOCHONDRIAL
(Bos
taurus) 		4 / 9 VAL H  36
HIS H  66
LEU H  93
VAL H  26
 None
 0.97A 6c2mD-2xndH:
undetectable		 6c2mD-2xndH:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_F_TA1F502_2
(TUBULIN BETA CHAIN)		 2xnd ATP SYNTHASE SUBUNIT
DELTA, MITOCHONDRIAL
ATP SYNTHASE SUBUNIT
EPSILON,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 LEU I  26
LEU H 141
THR H  99
PRO H  39
 None
 1.06A 6ew0F-2xndI:
undetectable		 6ew0F-2xndI:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_2
(TUBULIN BETA CHAIN)		 2xnd ATP SYNTHASE SUBUNIT
DELTA, MITOCHONDRIAL
ATP SYNTHASE SUBUNIT
EPSILON,
MITOCHONDRIAL
(Bos
taurus) 		4 / 6 LEU I  26
LEU H 141
THR H  99
PRO H  39
 None
 1.06A 6ew0G-2xndI:
undetectable		 6ew0G-2xndI:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G9B_B_IXXB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN
ENVELOPE
GLYCOPROTEIN)		 2xnd ATP SYNTHASE SUBUNIT
DELTA, MITOCHONDRIAL
ATP SYNTHASE SUBUNIT
EPSILON,
MITOCHONDRIAL
(Bos
taurus) 		4 / 5 ARG H 128
ALA H 129
TYR I   3
ILE H 135
 None
 1.47A 6g9bA-2xndH:
undetectable
6g9bB-2xndH:
undetectable		 6g9bA-2xndH:
23.44
6g9bB-2xndH:
17.83