SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xnq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NYR_B_SVRB401_2 (NAD-DEPENDENT DEACETYLASE SIRTUIN-5)	2xnq	NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3 (Saccharomyces cerevisiae)	4 / 6	PHE A 371 ARG A 331 GLN A 359 ASN A 341	None	1.14A	2nyrA-2xnqA: undetectable	2nyrA-2xnqA: 17.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2XNR_A_ACTA1001_0 (NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3)	2xnq	NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3 (Saccharomyces cerevisiae)	3 / 3	SER A 330 ARG A 331 GLN A 370	None	0.40A	2xnrA-2xnqA: 15.7	2xnrA-2xnqA: 100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ILT_H_TRUH800_1 (GLUTAMATE RECEPTOR 2)	2xnq	NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3 (Saccharomyces cerevisiae)	3 / 3	ILE A 369 SER A 376 SER A 330	None	0.46A	3iltH-2xnqA: undetectable	3iltH-2xnqA: 18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OI8_A_ADNA2_1 (UNCHARACTERIZED PROTEIN)	2xnq	NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3 (Saccharomyces cerevisiae)	4 / 6	ILE A 334 ASN A 389 PRO A 338 LEU A 337	None	1.26A	3oi8A-2xnqA: undetectable	3oi8A-2xnqA: 19.46

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2NYR_B_SVRB401_2","NAD-DEPENDENT DEACETYLASE SIRTUIN-5;NAD-DEPENDENT DEACETYLASE SIRTUIN-5","2xnq","NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3","Saccharomyces cerevisiae",4,"PHE A 371;ARG A 331;GLN A 359;ASN A 341","None","1.14A","2nyrA-2xnqA:undetectable","2nyrA-2xnqA:17.30"],["2XNR_A_ACTA1001_0","NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3","2xnq","NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3","Saccharomyces cerevisiae",3,"SER A 330;ARG A 331;GLN A 370","None","0.40A","2xnrA-2xnqA:15.7","2xnrA-2xnqA:100.00"],["3ILT_H_TRUH800_1","GLUTAMATE RECEPTOR 2","2xnq","NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3","Saccharomyces cerevisiae",3,"ILE A 369;SER A 376;SER A 330","None","0.46A","3iltH-2xnqA:undetectable","3iltH-2xnqA:18.43"],["3OI8_A_ADNA2_1","UNCHARACTERIZED PROTEIN","2xnq","NUCLEAR POLYADENYLATED RNA-BINDING PROTEIN 3","Saccharomyces cerevisiae",4,"ILE A 334;ASN A 389;PRO A 338;LEU A 337","None","1.26A","3oi8A-2xnqA:undetectable","3oi8A-2xnqA:19.46"]]