SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xod'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BU5_A_RBFA301_1
(PROTEIN (FLAVODOXIN))		 2xod NRDI PROTEIN
(Bacillus
anthracis) 		4 / 7 THR A   9
ASN A  11
THR A  42
GLY A  70
 FMN  A1119 (-3.5A)
FMN  A1119 (-3.5A)
FMN  A1119 (-3.7A)
FMN  A1119 (-3.2A)
 0.80A 1bu5A-2xodA:
12.6		 1bu5A-2xodA:
25.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_F_H3PF552_1
(GLUTAMATE
DEHYDROGENASE)		 2xod NRDI PROTEIN
(Bacillus
anthracis) 		4 / 7 ILE A  32
LYS A  64
ILE A  37
TYR A   5
 None
None
None
CAC  A1121 (-4.6A)
 1.06A 3eteD-2xodA:
undetectable
3eteF-2xodA:
undetectable		 3eteD-2xodA:
14.31
3eteF-2xodA:
14.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_B_SAMB303_0
(METHYLTRANSFERASE)		 2xod NRDI PROTEIN
(Bacillus
anthracis) 		5 / 12 ALA A   4
VAL A   3
ILE A  93
PHE A 109
ALA A  68
 None
 1.11A 5n5dB-2xodA:
undetectable		 5n5dB-2xodA:
19.64