SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xok'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA131_0
(FATTY ACID-BINDING
PROTEIN)		 2xok ATP SYNTHASE SUBUNIT
GAMMA, MITOCHONDRIAL
ATP SYNTHASE
(Saccharomyces
cerevisiae;
Saccharomyces
cerevisiae) 		5 / 11 THR G 213
LEU G 209
THR H  76
PHE G  51
GLN H  13
 None
 1.42A 1tw4A-2xokG:
undetectable		 1tw4A-2xokG:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YC5_A_NCAA2001_0
(NAD-DEPENDENT
DEACETYLASE)		 2xok ATP SYNTHASE SUBUNIT
GAMMA, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 7 ALA G 215
SER G 143
ILE G 146
ILE G 164
 None
 1.01A 1yc5A-2xokG:
undetectable		 1yc5A-2xokG:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 2xok ATP SYNTHASE SUBUNIT
GAMMA, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		6 / 10 GLU G 229
ILE G 133
GLY G 111
LEU G 150
ILE G  77
MET G 222
 None
 1.38A 3adsA-2xokG:
undetectable		 3adsA-2xokG:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UJ7_A_SAMA301_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 2xok ATP SYNTHASE SUBUNIT
GAMMA, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 12 LEU G 219
ILE G 133
ARG G  30
ASP G 136
ALA G 137
 None
 1.31A 3uj7A-2xokG:
undetectable		 3uj7A-2xokG:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 2xok ATP SYNTHASE SUBUNIT
GAMMA, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 12 GLY G 111
LYS G 115
ASP G 112
THR G 109
LEU G 128
 None
 1.26A 5hg0A-2xokG:
undetectable		 5hg0A-2xokG:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 2xok ATP SYNTHASE SUBUNIT
GAMMA, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		5 / 12 ILE G  39
PRO G 138
GLU G 142
LEU G 219
GLU G  35
 None
 1.47A 5mqtC-2xokG:
undetectable		 5mqtC-2xokG:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVS_B_ADNB401_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 2xok ATP SYNTHASE SUBUNIT
GAMMA, MITOCHONDRIAL
(Saccharomyces
cerevisiae) 		4 / 8 GLY G 245
GLU G  17
ASP G 238
ASN G 249
 None
 0.95A 5mvsB-2xokG:
2.6		 5mvsB-2xokG:
22.58