SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xp1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 2xp1 SPT6
(Antonospora
locustae) 		3 / 3 ASP A 933
TYR A 865
LYS A 853
 None
 0.76A 2othA-2xp1A:
undetectable		 2othA-2xp1A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_A_NCAA192_0
(NICOTINAMIDASE)		 2xp1 SPT6
(Antonospora
locustae) 		5 / 11 ASP A 944
ASP A 946
PHE A 905
HIS A 879
LEU A 935
 None
 1.30A 3o94A-2xp1A:
undetectable		 3o94A-2xp1A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_B_NCAB192_0
(NICOTINAMIDASE)		 2xp1 SPT6
(Antonospora
locustae) 		5 / 11 ASP A 944
ASP A 946
PHE A 905
HIS A 879
LEU A 935
 None
 1.29A 3o94B-2xp1A:
undetectable		 3o94B-2xp1A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_C_NCAC192_0
(NICOTINAMIDASE)		 2xp1 SPT6
(Antonospora
locustae) 		5 / 11 ASP A 944
ASP A 946
PHE A 905
HIS A 879
LEU A 935
 None
 1.30A 3o94C-2xp1A:
undetectable		 3o94C-2xp1A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O94_D_NCAD192_0
(NICOTINAMIDASE)		 2xp1 SPT6
(Antonospora
locustae) 		5 / 11 ASP A 944
ASP A 946
PHE A 905
HIS A 879
LEU A 935
 None
 1.29A 3o94D-2xp1A:
undetectable		 3o94D-2xp1A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 2xp1 SPT6
(Antonospora
locustae) 		4 / 4 PRO A 793
LEU A 794
ILE A 862
ARG A 867
 None
 1.08A 4f4dA-2xp1A:
undetectable		 4f4dA-2xp1A:
18.47