SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xq1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N4F_A_ASRA140_0
(LYSOZYME C)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		3 / 3 ASN A 394
ALA A 398
ASN A 400
 None
 0.76A 1n4fA-2xq1A:
undetectable		 1n4fA-2xq1A:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_B_EDTB1511_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		4 / 8 TYR A 213
TRP A 219
TYR A 221
THR A 209
 None
 1.33A 1zlqB-2xq1A:
undetectable		 1zlqB-2xq1A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		4 / 8 TYR A 478
ARG A 146
GLU A 181
TYR A 436
 None
 1.08A 2fl5E-2xq1A:
undetectable
2fl5F-2xq1A:
undetectable		 2fl5E-2xq1A:
18.66
2fl5F-2xq1A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_2
(THYMIDYLATE SYNTHASE)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		3 / 3 HIS A 302
ILE A 271
LEU A  90
 None
 0.70A 2kceA-2xq1A:
undetectable		 2kceA-2xq1A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 7 GLY A 107
GLY A 194
GLN A 185
PHE A 144
PHE A 154
 None
 1.47A 2qwxA-2xq1A:
undetectable
2qwxB-2xq1A:
undetectable		 2qwxA-2xq1A:
18.09
2qwxB-2xq1A:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		4 / 7 GLY A 194
GLN A 185
PHE A 144
PHE A 154
 None
 1.11A 2qx4A-2xq1A:
undetectable
2qx4B-2xq1A:
undetectable		 2qx4A-2xq1A:
17.43
2qx4B-2xq1A:
17.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_I_ASDI1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 9 TYR A 137
PHE A 226
LEU A 133
LEU A  90
PHE A 303
 None
 1.08A 2vcvI-2xq1A:
undetectable		 2vcvI-2xq1A:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		4 / 8 GLY A 121
ASN A 139
PHE A 144
ARG A 120
 None
 1.24A 3ccfA-2xq1A:
undetectable		 3ccfA-2xq1A:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFN_A_ROCA401_2
(HIV-1 PROTEASE)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		4 / 7 ARG A 117
GLY A 487
ILE A 486
VAL A 464
 None
 0.79A 3ufnB-2xq1A:
undetectable		 3ufnB-2xq1A:
12.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_A_HQEA503_1
(CATALASE)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 9 ASP A 118
PRO A 119
PHE A 144
LEU A 189
PHE A 190
 None
 0.47A 4qopA-2xq1A:
53.2		 4qopA-2xq1A:
44.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_B_HQEB503_1
(CATALASE)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 9 ASP A 118
PRO A 119
PHE A 144
LEU A 189
PHE A 190
 None
 0.47A 4qopB-2xq1A:
53.1		 4qopB-2xq1A:
44.40
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4QOP_C_HQEC503_1
(CATALASE)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 8 ASP A 118
PRO A 119
PHE A 144
LEU A 189
PHE A 190
 None
 0.46A 4qopC-2xq1A:
53.1		 4qopC-2xq1A:
44.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FPD_B_PZAB1385_0
(HEAT SHOCK-RELATED
70KDA PROTEIN 2)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		4 / 7 ASN A 234
VAL A 232
ALA A 228
GLY A 204
 None
 0.93A 5fpdB-2xq1A:
undetectable		 5fpdB-2xq1A:
21.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 12 VAL A 232
HIS A 225
ASN A 234
GLN A 185
GLY A 194
 None
 1.16A 6gnfA-2xq1A:
undetectable		 6gnfA-2xq1A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 12 VAL A 232
HIS A 295
ASN A 234
GLN A 185
GLY A 194
 None
 1.17A 6gnfA-2xq1A:
undetectable		 6gnfA-2xq1A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 12 VAL A 232
HIS A 225
ASN A 234
GLN A 185
GLY A 194
 None
 1.16A 6gnfC-2xq1A:
undetectable		 6gnfC-2xq1A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_C_QPSC602_2
(-)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 12 VAL A 232
HIS A 295
ASN A 234
GLN A 185
GLY A 194
 None
 1.16A 6gnfC-2xq1A:
undetectable		 6gnfC-2xq1A:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GSD_A_STRA401_0
(PROGESTERONE
5-BETA-REDUCTASE)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		5 / 12 ARG A 344
VAL A 340
PHE A 154
ILE A 145
ASN A 138
 None
 1.45A 6gsdA-2xq1A:
undetectable		 6gsdA-2xq1A:
9.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 2xq1 PEROXISOMAL CATALASE
(Ogataea
angusta) 		3 / 3 ASP A 247
LEU A 243
ARG A 120
 None
 0.83A 7dfrA-2xq1A:
undetectable		 7dfrA-2xq1A:
14.83