SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xqh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 12 GLY A 173
GLY A 201
ALA A 192
ALA A 206
ASP A 193
 None
 1.06A 3keeA-2xqhA:
undetectable		 3keeA-2xqhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 12 GLY A 166
GLY A 194
SER A 183
ALA A 185
ALA A 199
 None
 1.11A 3keeB-2xqhA:
undetectable		 3keeB-2xqhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_C_30BC500_1
(GENOME POLYPROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 12 GLY A 173
GLY A 201
ALA A 192
ALA A 206
ASP A 193
 None
 0.99A 3keeC-2xqhA:
undetectable		 3keeC-2xqhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 12 GLY A 166
GLY A 194
SER A 183
ALA A 185
ALA A 199
 None
 1.12A 3keeD-2xqhA:
undetectable		 3keeD-2xqhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 12 GLY A 173
GLY A 201
ALA A 192
ALA A 206
ASP A 193
 None
 1.08A 3keeD-2xqhA:
undetectable		 3keeD-2xqhA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_A_SUEA1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 12 GLY A 173
GLY A 201
ALA A 190
ALA A 192
ALA A 206
 None
 0.98A 3sudA-2xqhA:
undetectable		 3sudA-2xqhA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 12 GLY A 173
GLY A 201
ALA A 190
ALA A 192
ALA A 206
 None
 0.99A 3sudC-2xqhA:
undetectable		 3sudC-2xqhA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUD_D_SUED1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		7 / 12 GLY A 173
GLY A 201
ALA A 190
ALA A 192
ALA A 206
SER A 211
ASP A 193
 None
 1.44A 3sudD-2xqhA:
undetectable		 3sudD-2xqhA:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 12 GLY A 166
GLY A 194
SER A 183
ALA A 185
ALA A 199
 None
 1.07A 3sueC-2xqhA:
undetectable		 3sueC-2xqhA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_C_SUEC1201_1
(NS3 PROTEASE, NS4A
PROTEIN)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 11 GLY A 166
GLY A 194
SER A 183
ALA A 185
ALA A 199
 None
 1.09A 3sufC-2xqhA:
undetectable		 3sufC-2xqhA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 2xqh IMMUNOGLOBULIN-BINDI
NG PROTEIN EIBD
(Escherichia
coli) 		5 / 9 THR A 198
LEU A 214
GLY A 215
THR A 204
VAL A 186
 None
 1.45A 4c9kB-2xqhA:
undetectable		 4c9kB-2xqhA:
21.43