SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '2xqx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FOP_A_H4BA1600_1
(NITRIC-OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 1fopA-2xqxA:
0.0
1fopB-2xqxA:
0.0		 1fopA-2xqxA:
15.12
1fopB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZS_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.50A 1zzsA-2xqxA:
undetectable
1zzsB-2xqxA:
undetectable		 1zzsA-2xqxA:
16.22
1zzsB-2xqxA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 3dqsA-2xqxA:
0.0
3dqsB-2xqxA:
0.0		 3dqsA-2xqxA:
15.50
3dqsB-2xqxA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 7 VAL A 849
MET A 864
ILE A 940
ILE A 938
 None
 1.02A 3hgxA-2xqxA:
undetectable		 3hgxA-2xqxA:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.45A 3jwxA-2xqxA:
0.0
3jwxB-2xqxA:
0.0		 3jwxA-2xqxA:
15.12
3jwxB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 3jwxA-2xqxA:
0.0
3jwxB-2xqxA:
0.0		 3jwxA-2xqxA:
15.12
3jwxB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 3jwyA-2xqxA:
0.0
3jwyB-2xqxA:
0.0		 3jwyA-2xqxA:
15.12
3jwyB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 3jwyA-2xqxA:
0.0
3jwyB-2xqxA:
0.0		 3jwyA-2xqxA:
15.12
3jwyB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 3jwzA-2xqxA:
0.0
3jwzB-2xqxA:
0.0		 3jwzA-2xqxA:
15.12
3jwzB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 3jwzA-2xqxA:
0.0
3jwzB-2xqxA:
0.0		 3jwzA-2xqxA:
15.12
3jwzB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 3n5pA-2xqxA:
0.0
3n5pB-2xqxA:
0.0		 3n5pA-2xqxA:
15.12
3n5pB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5R_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 3n5rA-2xqxA:
undetectable
3n5rB-2xqxA:
undetectable		 3n5rA-2xqxA:
15.12
3n5rB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.45A 3n5sA-2xqxA:
undetectable
3n5sB-2xqxA:
undetectable		 3n5sA-2xqxA:
15.12
3n5sB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5S_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 3n5sA-2xqxA:
undetectable
3n5sB-2xqxA:
undetectable		 3n5sA-2xqxA:
15.12
3n5sB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 7 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.46A 3n5tA-2xqxA:
undetectable
3n5tB-2xqxA:
undetectable		 3n5tA-2xqxA:
15.12
3n5tB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5T_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 3n5tA-2xqxA:
undetectable
3n5tB-2xqxA:
undetectable		 3n5tA-2xqxA:
15.12
3n5tB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N61_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 3n61A-2xqxA:
undetectable
3n61B-2xqxA:
undetectable		 3n61A-2xqxA:
14.93
3n61B-2xqxA:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 3n6eA-2xqxA:
0.0
3n6eB-2xqxA:
0.0		 3n6eA-2xqxA:
15.80
3n6eB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6E_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 3n6eA-2xqxA:
undetectable
3n6eB-2xqxA:
undetectable		 3n6eA-2xqxA:
15.80
3n6eB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_A_H4BA600_1
('NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 3n6fA-2xqxA:
undetectable
3n6fB-2xqxA:
undetectable		 3n6fA-2xqxA:
15.80
3n6fB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6F_B_H4BB600_1
('NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 3n6fA-2xqxA:
0.0
3n6fB-2xqxA:
0.0		 3n6fA-2xqxA:
15.80
3n6fB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 3n6gA-2xqxA:
undetectable
3n6gB-2xqxA:
undetectable		 3n6gA-2xqxA:
15.80
3n6gB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N6G_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.45A 3n6gA-2xqxA:
0.0
3n6gB-2xqxA:
0.0		 3n6gA-2xqxA:
15.80
3n6gB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLD_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 3nldA-2xqxA:
0.0
3nldB-2xqxA:
0.0		 3nldA-2xqxA:
15.12
3nldB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.45A 3nleA-2xqxA:
0.0
3nleB-2xqxA:
0.0		 3nleA-2xqxA:
15.12
3nleB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLE_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.50A 3nleA-2xqxA:
0.0
3nleB-2xqxA:
0.0		 3nleA-2xqxA:
15.12
3nleB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLF_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.44A 3nlfA-2xqxA:
0.0
3nlfB-2xqxA:
0.0		 3nlfA-2xqxA:
15.12
3nlfB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 3nlgA-2xqxA:
undetectable
3nlgB-2xqxA:
undetectable		 3nlgA-2xqxA:
15.12
3nlgB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLG_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 3nlgA-2xqxA:
undetectable
3nlgB-2xqxA:
undetectable		 3nlgA-2xqxA:
15.12
3nlgB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.46A 3nlhA-2xqxA:
0.0
3nlhB-2xqxA:
0.0		 3nlhA-2xqxA:
15.80
3nlhB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 3nlhA-2xqxA:
0.0
3nlhB-2xqxA:
0.0		 3nlhA-2xqxA:
15.80
3nlhB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.47A 3nliA-2xqxA:
0.0
3nliB-2xqxA:
0.0		 3nliA-2xqxA:
15.80
3nliB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLI_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 3nliA-2xqxA:
0.0
3nliB-2xqxA:
0.0		 3nliA-2xqxA:
15.80
3nliB-2xqxA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLU_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 3nluA-2xqxA:
0.0
3nluB-2xqxA:
0.0		 3nluA-2xqxA:
15.12
3nluB-2xqxA:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OKX_B_SAMB201_0
(YAEB-LIKE PROTEIN
RPA0152)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		3 / 3 LYS A 889
ARG A 923
LYS A 818
 None
 1.40A 3okxA-2xqxA:
undetectable		 3okxA-2xqxA:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 3pnhA-2xqxA:
0.0
3pnhB-2xqxA:
0.0		 3pnhA-2xqxA:
15.50
3pnhB-2xqxA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNH_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.49A 3pnhA-2xqxA:
0.0
3pnhB-2xqxA:
0.0		 3pnhA-2xqxA:
15.50
3pnhB-2xqxA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQO_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.45A 3rqoA-2xqxA:
0.0
3rqoB-2xqxA:
0.0		 3rqoA-2xqxA:
15.23
3rqoB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQP_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.46A 3rqpA-2xqxA:
0.0
3rqpB-2xqxA:
0.0		 3rqpA-2xqxA:
15.23
3rqpB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 GLY A 893
TRP A 895
ARG A 852
ARG A 923
 None
 1.21A 4bqfA-2xqxA:
undetectable		 4bqfA-2xqxA:
11.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 4c3aA-2xqxA:
undetectable
4c3aB-2xqxA:
undetectable		 4c3aA-2xqxA:
15.23
4c3aB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C3A_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 4c3aA-2xqxA:
undetectable
4c3aB-2xqxA:
undetectable		 4c3aA-2xqxA:
15.23
4c3aB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.45A 4carA-2xqxA:
0.0
4carB-2xqxA:
0.0		 4carA-2xqxA:
15.23
4carB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTY_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 4ctyA-2xqxA:
0.0
4ctyB-2xqxA:
0.0		 4ctyA-2xqxA:
15.23
4ctyB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 4ctzA-2xqxA:
0.0
4ctzB-2xqxA:
0.0		 4ctzA-2xqxA:
15.23
4ctzB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.45A 4ctzA-2xqxA:
0.0
4ctzB-2xqxA:
0.0		 4ctzA-2xqxA:
15.23
4ctzB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.47A 4cu0A-2xqxA:
0.0
4cu0B-2xqxA:
0.0		 4cu0A-2xqxA:
15.23
4cu0B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CU0_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 4cu0A-2xqxA:
undetectable
4cu0B-2xqxA:
undetectable		 4cu0A-2xqxA:
15.23
4cu0B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 4cwwA-2xqxA:
0.0
4cwwB-2xqxA:
0.0		 4cwwA-2xqxA:
15.23
4cwwB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWW_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 4cwwA-2xqxA:
undetectable
4cwwB-2xqxA:
undetectable		 4cwwA-2xqxA:
15.23
4cwwB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.45A 4cwxA-2xqxA:
undetectable
4cwxB-2xqxA:
undetectable		 4cwxA-2xqxA:
15.23
4cwxB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWX_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 7 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 4cwxA-2xqxA:
undetectable
4cwxB-2xqxA:
undetectable		 4cwxA-2xqxA:
15.23
4cwxB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWY_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 7 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 4cwyA-2xqxA:
undetectable
4cwyB-2xqxA:
undetectable		 4cwyA-2xqxA:
15.23
4cwyB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.47A 4cwzA-2xqxA:
undetectable
4cwzB-2xqxA:
undetectable		 4cwzA-2xqxA:
14.90
4cwzB-2xqxA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CWZ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.49A 4cwzA-2xqxA:
undetectable
4cwzB-2xqxA:
undetectable		 4cwzA-2xqxA:
14.90
4cwzB-2xqxA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX0_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 4cx0A-2xqxA:
0.0
4cx0B-2xqxA:
0.0		 4cx0A-2xqxA:
14.90
4cx0B-2xqxA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.49A 4d1pA-2xqxA:
undetectable
4d1pB-2xqxA:
undetectable		 4d1pA-2xqxA:
14.58
4d1pB-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D36_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 4d36A-2xqxA:
undetectable
4d36B-2xqxA:
undetectable		 4d36A-2xqxA:
15.23
4d36B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D37_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 4d37A-2xqxA:
0.0
4d37B-2xqxA:
0.0		 4d37A-2xqxA:
15.23
4d37B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_A_H4BA502_1
(SUBUNIT A)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 4imxA-2xqxA:
undetectable
4imxB-2xqxA:
undetectable		 4imxA-2xqxA:
15.35
4imxB-2xqxA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMX_B_H4BB502_1
(SUBUNIT A)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 4imxA-2xqxA:
0.0
4imxB-2xqxA:
0.0		 4imxA-2xqxA:
15.35
4imxB-2xqxA:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSK_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.41A 4jskA-2xqxA:
0.0
4jskB-2xqxA:
0.0		 4jskA-2xqxA:
15.23
4jskB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 4jslA-2xqxA:
0.0
4jslB-2xqxA:
0.0		 4jslA-2xqxA:
15.23
4jslB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSL_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 4jslA-2xqxA:
0.0
4jslB-2xqxA:
0.0		 4jslA-2xqxA:
15.23
4jslB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5I_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.47A 4k5iA-2xqxA:
undetectable
4k5iB-2xqxA:
undetectable		 4k5iA-2xqxA:
15.23
4k5iB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 4k5kA-2xqxA:
undetectable
4k5kB-2xqxA:
undetectable		 4k5kA-2xqxA:
15.23
4k5kB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5K_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 4k5kA-2xqxA:
0.0
4k5kB-2xqxA:
0.0		 4k5kA-2xqxA:
15.23
4k5kB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.45A 4kcpA-2xqxA:
undetectable
4kcpB-2xqxA:
undetectable		 4kcpA-2xqxA:
15.23
4kcpB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCP_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 4kcpA-2xqxA:
undetectable
4kcpB-2xqxA:
undetectable		 4kcpA-2xqxA:
15.23
4kcpB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.50A 4kcqA-2xqxA:
undetectable
4kcqB-2xqxA:
undetectable		 4kcqA-2xqxA:
15.23
4kcqB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCQ_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 4kcqA-2xqxA:
undetectable
4kcqB-2xqxA:
undetectable		 4kcqA-2xqxA:
15.23
4kcqB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 4kcrA-2xqxA:
0.0
4kcrB-2xqxA:
0.0		 4kcrA-2xqxA:
15.23
4kcrB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCR_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.50A 4kcrA-2xqxA:
undetectable
4kcrB-2xqxA:
undetectable		 4kcrA-2xqxA:
15.23
4kcrB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCS_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.45A 4kcsA-2xqxA:
0.0
4kcsB-2xqxA:
0.0		 4kcsA-2xqxA:
15.23
4kcsB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUW_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 4luwA-2xqxA:
0.0
4luwB-2xqxA:
0.0		 4luwA-2xqxA:
14.58
4luwB-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 4uh7A-2xqxA:
0.0
4uh7B-2xqxA:
undetectable		 4uh7A-2xqxA:
15.23
4uh7B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH7_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 4uh7A-2xqxA:
0.0
4uh7B-2xqxA:
0.0		 4uh7A-2xqxA:
15.23
4uh7B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH8_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 4uh8A-2xqxA:
undetectable
4uh8B-2xqxA:
undetectable		 4uh8A-2xqxA:
15.23
4uh8B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH9_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 4uh9A-2xqxA:
undetectable
4uh9B-2xqxA:
undetectable		 4uh9A-2xqxA:
15.23
4uh9B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UHA_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.47A 4uhaA-2xqxA:
undetectable
4uhaB-2xqxA:
undetectable		 4uhaA-2xqxA:
15.23
4uhaB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPQ_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 4upqA-2xqxA:
undetectable
4upqB-2xqxA:
undetectable		 4upqA-2xqxA:
15.23
4upqB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.47A 4uprA-2xqxA:
0.0
4uprB-2xqxA:
0.0		 4uprA-2xqxA:
15.23
4uprB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPR_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 4uprA-2xqxA:
0.0
4uprB-2xqxA:
0.0		 4uprA-2xqxA:
15.23
4uprB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 4upsA-2xqxA:
0.0
4upsB-2xqxA:
0.0		 4upsA-2xqxA:
15.23
4upsB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPS_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.49A 4upsA-2xqxA:
0.0
4upsB-2xqxA:
0.0		 4upsA-2xqxA:
15.23
4upsB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.47A 4uptA-2xqxA:
0.0
4uptB-2xqxA:
0.0		 4uptA-2xqxA:
15.23
4uptB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPT_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.43A 4uptA-2xqxA:
0.0
4uptB-2xqxA:
0.0		 4uptA-2xqxA:
15.23
4uptB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADM_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 5admA-2xqxA:
undetectable
5admB-2xqxA:
undetectable		 5admA-2xqxA:
15.23
5admB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FJ2_A_H4BA600_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.50A 5fj2A-2xqxA:
undetectable
5fj2B-2xqxA:
undetectable		 5fj2A-2xqxA:
15.23
5fj2B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_A_H4BA600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 5fvzA-2xqxA:
undetectable
5fvzB-2xqxA:
0.0		 5fvzA-2xqxA:
15.23
5fvzB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVZ_B_H4BB600_1
(ENDOTHELIAL NITRIC
OXIDE SYNTHASE)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 5fvzA-2xqxA:
0.0
5fvzB-2xqxA:
0.0		 5fvzA-2xqxA:
15.23
5fvzB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_E_SAME301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		5 / 12 ASP A 930
ALA A 937
GLY A 847
SER A 848
SER A 929
 None
 1.27A 5hfjE-2xqxA:
undetectable		 5hfjE-2xqxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_F_SAMF301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		5 / 12 ASP A 930
ALA A 937
GLY A 847
SER A 848
SER A 929
 None
 1.12A 5hfjF-2xqxA:
undetectable		 5hfjF-2xqxA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.44A 5uo8A-2xqxA:
undetectable
5uo8B-2xqxA:
undetectable		 5uo8A-2xqxA:
14.58
5uo8B-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.44A 5uo8C-2xqxA:
0.0
5uo8D-2xqxA:
0.0		 5uo8C-2xqxA:
14.58
5uo8D-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO8_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 5uo8C-2xqxA:
0.0
5uo8D-2xqxA:
0.0		 5uo8C-2xqxA:
14.58
5uo8D-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO9_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 7 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 5uo9C-2xqxA:
undetectable
5uo9D-2xqxA:
undetectable		 5uo9C-2xqxA:
14.58
5uo9D-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.50A 5uodA-2xqxA:
undetectable
5uodB-2xqxA:
undetectable		 5uodA-2xqxA:
15.23
5uodB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UOD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.50A 5uodA-2xqxA:
0.0
5uodB-2xqxA:
0.0		 5uodA-2xqxA:
15.23
5uodB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV6_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.48A 5vv6A-2xqxA:
0.0
5vv6B-2xqxA:
0.0		 5vv6A-2xqxA:
15.23
5vv6B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV8_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 5vv8A-2xqxA:
0.0
5vv8B-2xqxA:
0.0		 5vv8A-2xqxA:
15.23
5vv8B-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVB_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.49A 5vvbA-2xqxA:
0.0
5vvbB-2xqxA:
0.0		 5vvbA-2xqxA:
14.58
5vvbB-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 5vvcA-2xqxA:
0.0
5vvcB-2xqxA:
0.0		 5vvcA-2xqxA:
14.58
5vvcB-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.49A 5vvcC-2xqxA:
0.0
5vvcD-2xqxA:
0.0		 5vvcC-2xqxA:
14.58
5vvcD-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVC_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.48A 5vvcC-2xqxA:
undetectable
5vvcD-2xqxA:
undetectable		 5vvcC-2xqxA:
14.58
5vvcD-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 7 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 5vvdA-2xqxA:
undetectable
5vvdB-2xqxA:
undetectable		 5vvdA-2xqxA:
14.58
5vvdB-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVD_C_H4BC502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.47A 5vvdC-2xqxA:
undetectable
5vvdD-2xqxA:
undetectable		 5vvdC-2xqxA:
14.58
5vvdD-2xqxA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVG_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.46A 5vvgA-2xqxA:
0.0
5vvgB-2xqxA:
0.0		 5vvgA-2xqxA:
15.23
5vvgB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 VAL A 811
TRP A 840
PHE A 816
GLU A 826
 None
 1.45A 5vvnA-2xqxA:
0.0
5vvnB-2xqxA:
0.0		 5vvnA-2xqxA:
15.23
5vvnB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 7 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 5vvnA-2xqxA:
undetectable
5vvnB-2xqxA:
undetectable		 5vvnA-2xqxA:
15.23
5vvnB-2xqxA:
15.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB503_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 7 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.49A 6av6A-2xqxA:
undetectable
6av6B-2xqxA:
undetectable		 6av6A-2xqxA:
18.37
6av6B-2xqxA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIE_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 7 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.46A 6cieA-2xqxA:
undetectable
6cieB-2xqxA:
undetectable		 6cieA-2xqxA:
18.37
6cieB-2xqxA:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIF_B_H4BB502_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 2xqx ENDO-BETA-N-ACETYLGL
UCOSAMINIDASE D
(Streptococcus
pneumoniae) 		4 / 6 TRP A 840
PHE A 816
GLU A 826
VAL A 811
 None
 1.47A 6cifA-2xqxA:
0.0
6cifB-2xqxA:
0.0		 6cifA-2xqxA:
18.37
6cifB-2xqxA:
18.37